Opthodex S

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  • Manufactured by: Optho Remedies Pvt Ltd
  • Contains / Salt: Chloramphenicol (0.5 % w/v) + Dexamethasone (0.1 % w/v)

Opthodex S Information

Opthodex S, a prescription drug, is manufactured in various forms such as Drops. The alternative uses of Opthodex S have also been explained below.

Medical history of the patient along with age and gender determines the dosage of Opthodex S. Besides the medical condition it is advised for, the route of administration also plays an important role in determining the correct drug dosage. Detailed information has been provided in the dosage section.

Opthodex S also has some side effects, the most common being Eye Burning, Eye irritation. Such side effects of Opthodex S normally do not last long and go away once the treatment is completed. If, however, they worsen or do not go away, please speak with your physician.

In addition, Opthodex S's effect is Unknown during pregnancy and Unknown for lactating mothers. Warnings related to Opthodex S's effects on the liver, heart and kidney, if any, have been listed below.

Individuals suffering from medical conditions like Kidney Disease, Liver Disease, Infections must refrain from the use of Opthodex S since this can cause severe adverse effects. Other contraindications of Opthodex S have been discussed in the sections ahead.

Drug interactions for Opthodex S have been reported in the medical literature. See below for a complete list.

In addition to the above precautions for Opthodex S, it is important to know that it is not safe while driving, and is not habit-forming.


Opthodex S Benefits & Uses

Opthodex S is used to treat the following -

Other Benefits

Opthodex S Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
13 - 18 years (Adolescent)
  • Disease:
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 2 drop
  • Dosage Route: Ophthalmic
  • Frequency: 4 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: Dosage strength: Chloramphenicol (1%) + Dexamethasone (0.1%)
Adult
  • Disease:
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 2 drop
  • Dosage Route: Ophthalmic
  • Frequency: 4 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: Dosage strength: Chloramphenicol (1%) + Dexamethasone (0.1%)
Geriatric
  • Disease:
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 2 drop
  • Dosage Route: Ophthalmic
  • Frequency: 4 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: Dosage strength: Chloramphenicol (1%) + Dexamethasone (0.1%)

Opthodex S Side Effects

Based on research, the following side effects have been observed when Opthodex S is used -

Common

  • Eye Burning
  • Eye irritation

Opthodex S Related Warnings

  • Is the use of Opthodex S safe for pregnant women?


    The effects of Opthodex S on pregnant women are unknown since no research has been done to ascertain it yet.

    Unknown
  • Is the use of Opthodex S safe during breastfeeding?


    Due to lack of research work on this topic, the side effects of Opthodex S for breastfeeding women are not known.

    Unknown
  • What is the effect of Opthodex S on the Kidneys?


    There is no research available on the side effects of Opthodex S on kidney. Therefore, its impact is unknown.

    Unknown
  • What is the effect of Opthodex S on the Liver?


    Information about safety of Opthodex S for the liver is not available since scientific research on this is yet to be done.

    Unknown
  • What is the effect of Opthodex S on the Heart?


    There is no research available on the side effects of Opthodex S on the heart. Therefore, its impact is unknown.

    Unknown

Severe Interaction of Opthodex S with Other Drugs

Opthodex S should not be taken with following medicines due to severe side effects it may cause to patients -

Severe

Moderate


Opthodex S Contraindications

If you are suffering from any of the following diseases, you should not take Opthodex S unless your doctor advises you to do so -


Frequently asked Questions about Opthodex S

  • Is this Opthodex S habit forming or addictive?


    No, there is no any evidence that Opthodex S is addictive.

    No
  • Is it safe to drive or operate heavy machinery when consuming?


    No, you should not drive or operate heavy machinery after taking Opthodex S as you may feel sleepy.

    Dangerous
  • Is it safe?


    Yes, but consume Opthodex S only on doctor's advice.

    Safe, but take only on Doctor's advise
  • Is it able to treat mental disorders?


    No, the use of Opthodex S in mental disorders is not effective.

    No

Opthodex S Interactions with Food and Alcohol

  • Interaction between Food and Opthodex S


    Due to the absence of research, it is difficult to say how Opthodex S and food will interact.

    Unknown
  • Interaction between Alcohol and Opthodex S


    Information about the interaction of Opthodex S and alcohol is not currently available because this topic has not been researched yet.

    Unknown

Frequently asked Questions about Opthodex S

Question about 6 years ago

Is Opthodex S helpful in typhoid?

Dr. Piyush Malav MBBS, MS , General Surgery

Yes, Opthodex S is helpful in typhoid fever. It is used in the management of acute typhoid fever caused by Salmonella species. It is usually given after 8 -10 days of the treatment when the fever of the patient is completely going down over this duration to prevent the relapse of the typhoid infection.

Question about 7 years ago

What is Opthodex S?

Dr. Sameer Awadhiya MBBS , Pediatrics

Opthodex S is a brand name of chloramphenicol and it comes in the various dosage forms such as an oral tablet, capsule, syrup, and eye drops. It is a prescription drug that belongs to the class of medications called amphenicols. It is a broad spectrum antibiotic which is active against a wide variety of gram-positive and gram-negative bacteria. It is mainly used in the treatment of psittacosis also known as parrot fever, rickettsial infection, cystic fibrosis, pneumonia, and also sometimes in the management of typhoid fever.

Question about 6 years ago

Can Opthodex S treat meningitis?

Dr Anjum Mujawar MBBS, MBBS , Emergency Medicine

Yes, Opthodex S can treat meningitis. It is a bacterial infection caused by Neisseria meningitidis that causes inflammation of the meninges around the brain and spinal cord. The duration of the treatment is usually 2 weeks.

Question about 7 years ago

Does Opthodex S cause gray baby syndrome?

Dr. Tarun kumar MBBS , Other

Yes, Opthodex S may cause gray baby syndorme in newborn infants especially in premature baby, if this drug is given in higher doses. Gray baby syndrome is a rare side effect that occurs due to accumulation of the chloramphenicol in the newborn infant. The cause of gray baby syndrome is that the newborn baby lacks the some liver enzymes which are necessary to metabolize and removes this drug from the body. The accumulation of the chloramphenicol in the body leads to toxicity which causes development of symptoms such as vomiting, gray color of the skin, blue discolouration of lips and skin. To avoid gray baby syndrome the doses of Opthodex S must be lowered and adjusted as per the need.

Question over 6 years ago

Does Opthodex S cause weight loss?

Dr. Ajay Kumar. MBBS, MD , Psychiatry, General Physician, Infectious Disease, Sexology, Internal Medicine, Venereology, Diabetology

No, Opthodex S does not cause weight loss. It has not been reported by the patients who are taking this drug. However, some of the animal studies have reported weight loss after long-term use of this drug. If you are experiencing unusual weight loss and you are in doubt that Opthodex S is causing weight loss then discuss with your doctor instantly. 


See all substitutes for Opthodex S


This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
7 Years of Experience


References

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Chloromycetin sodium succinate (chaloramphenicol sodium succinate)

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 739-742

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 362-366

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 289

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Decadron® (dexamethasone)

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Hemady™ (dexamethasone)

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Hexadrol® (dexamethasone sodium phosphate)

National Institutes of Health U.S. National Library of Medicine [Internet]: Dexamethasone Ophthalmic. American Society of Health-System Pharmacists

Package Leaflet Information For The User [Internet]: Chloramphenicol 1% w/w Eye Ointment. Martindale Pharmaceuticals Ltd

leaflet [Internet]: Minims® Dexamethasone Sodium Phosphate 0.1% w/v. Minims

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