Polydex

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Polydex Information

Polydex is a commercial drug that is prescribed in the form of Drops. Polydex also has some secondary and off-label uses. These are listed below.

The right dosage of Polydex depends on the age, gender, and medical history of the patient. Individual symptoms and route of administration also determines the right dosage. For detailed information on this, read through the dosage section.

The side effects typically associated with Polydex include Eye Burning, Eye irritation. Normally, these side effects of Polydex are not long lasting and go away when the treatment is finished. However, if these continue for a longer time, consult your doctor right away.

It is also important to note that Polydex has a Unknown effect for pregnant women and Unknown effect on lactating mothers. Further, the section on Polydex related warnings talks about Polydex's effects on the liver, heart and kidney.

Polydex can cause adverse effects in certain medical conditions. It is strongly recommended to avoid Polydex in conditions like Kidney Disease, Liver Disease, Infections. The section on Polydex contraindications lists all such conditions.

Drug reaction of Polydex with other medicines has been reported. See below for a complete list.

In addition to these precautions, you may also note that Polydex is not safe while driving, and is is not addictive in nature.


Polydex Benefits & Uses

Polydex is used to treat the following -

Other Benefits

Polydex Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
13 - 18 years (Adolescent)
  • Disease:
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 2 drop
  • Dosage Route: Ophthalmic
  • Frequency: 4 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: Dosage strength: Chloramphenicol (1%) + Dexamethasone (0.1%)
Adult
  • Disease:
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 2 drop
  • Dosage Route: Ophthalmic
  • Frequency: 4 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: Dosage strength: Chloramphenicol (1%) + Dexamethasone (0.1%)
Geriatric
  • Disease:
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 2 drop
  • Dosage Route: Ophthalmic
  • Frequency: 4 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: Dosage strength: Chloramphenicol (1%) + Dexamethasone (0.1%)

Polydex Side Effects

Based on research, the following side effects have been observed when Polydex is used -

Common

  • Eye Burning
  • Eye irritation

Polydex Related Warnings

  • Is the use of Polydex safe for pregnant women?


    The effects of Polydex on pregnant women are unknown since no research has been done to ascertain it yet.

    Unknown
  • Is the use of Polydex safe during breastfeeding?


    In the absence of any scientific study about the side effects of Polydex in breastfeeding women, information on safety of Polydex is unavailable.

    Unknown
  • What is the effect of Polydex on the Kidneys?


    There is no research available on the side effects of Polydex on kidney. Therefore, its impact is unknown.

    Unknown
  • What is the effect of Polydex on the Liver?


    So far, no research has been carried out on the effects of Polydex on the liver. So it is not known whether taking Polydex will affect the liver or not.

    Unknown
  • What is the effect of Polydex on the Heart?


    No research work has been carried out till date on effects of Polydex on heart. So it is not known whether taking Polydex will cause side effects on heart or not.

    Unknown

Severe Interaction of Polydex with Other Drugs

Polydex should not be taken with following medicines due to severe side effects it may cause to patients -

Severe

Moderate


Polydex Contraindications

If you are suffering from any of the following diseases, you should not take Polydex unless your doctor advises you to do so -


Frequently asked Questions about Polydex

  • Is this Polydex habit forming or addictive?


    Polydex does not cause addiction.

    No
  • Is it safe to drive or operate heavy machinery when consuming?


    After taking Polydex you may feel sleepy. So it is not advised to perform these activities.

    Dangerous
  • Is it safe?


    Yes, but consume Polydex only on doctor's advice.

    Safe, but take only on Doctor's advise
  • Is it able to treat mental disorders?


    Polydex is unable to treat or cure mental disorders.

    No

Polydex Interactions with Food and Alcohol

  • Interaction between Food and Polydex


    Due to a lack of research, nothing can be said about the consequences of taking Polydex together with food.

    Unknown
  • Interaction between Alcohol and Polydex


    Due to lack of research, there is no information about the side effects of taking Polydex with alcohol.

    Unknown

Frequently asked Questions about Polydex

Question almost 7 years ago

Is Polydex safe to use?

Dr. R.K Singh MBBS , Diabetology

Yes, Polydex is safe to use, if taken in prescribed amount and duration as advised by the doctor. However, certain side effects have been associated with this drug such as a headache, nausea, and vomiting. If you experience any of the above conditions after taking this medicine then do not hesitate to inform your doctor and follow his/her instructions.

Question about 7 years ago

Does Polydex cause gray baby syndrome?

Dr. Tarun kumar MBBS , Other

Yes, Polydex may cause gray baby syndorme in newborn infants especially in premature baby, if this drug is given in higher doses. Gray baby syndrome is a rare side effect that occurs due to accumulation of the chloramphenicol in the newborn infant. The cause of gray baby syndrome is that the newborn baby lacks the some liver enzymes which are necessary to metabolize and removes this drug from the body. The accumulation of the chloramphenicol in the body leads to toxicity which causes development of symptoms such as vomiting, gray color of the skin, blue discolouration of lips and skin. To avoid gray baby syndrome the doses of Polydex must be lowered and adjusted as per the need.

Question over 5 years ago

Can I take Polydex with ibuprofen?

Dr. Surender Kumar MBBS , General Physician

Yes, Polydex can be taken with ibuprofen. No harmful drug interaction has been reported between them. However, if you feel any discomfort after taking this drug do not hesitate to inform your doctor.

Question almost 6 years ago

Is Polydex an antibiotic?

Dr. MBBS , Pediatrics, Dermatology, General Physician, Dietician, Infectious Disease, Sexual Medicine & Marital Therapy, Obstetrics & Gynaecology, AIDS/HIV Sexually Transmitted Infections

Yes, Polydex is an antibiotic. It contains chloramphenicol which is a broad spectrum antibiotic that belongs to the class of drugs known as amphenicols. It is used for the prevention and treatment of various bacterial infections. It is mainly used in the treatment of parrot fever, rickettsial infection, cystic fibrosis, pneumonia, and also sometimes in the management of typhoid fever.

Question about 6 years ago

Is Polydex helpful in typhoid?

Dr. Piyush Malav MBBS, MS , General Surgery

Yes, Polydex is helpful in typhoid fever. It is used in the management of acute typhoid fever caused by Salmonella species. It is usually given after 8 -10 days of the treatment when the fever of the patient is completely going down over this duration to prevent the relapse of the typhoid infection.


See all substitutes for Polydex


This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
7 Years of Experience


References

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Chloromycetin sodium succinate (chaloramphenicol sodium succinate)

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 739-742

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 362-366

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 289

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Decadron® (dexamethasone)

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Hemady™ (dexamethasone)

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Hexadrol® (dexamethasone sodium phosphate)

National Institutes of Health U.S. National Library of Medicine [Internet]: Dexamethasone Ophthalmic. American Society of Health-System Pharmacists

Package Leaflet Information For The User [Internet]: Chloramphenicol 1% w/w Eye Ointment. Martindale Pharmaceuticals Ltd

leaflet [Internet]: Minims® Dexamethasone Sodium Phosphate 0.1% w/v. Minims

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