Sulphadiazine

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Sulphadiazine Information

Sulphadiazine, a prescription drug, is manufactured in various forms such as Tablet. Toxoplasmosis are some of its major therapeutic uses. The alternative uses of Sulphadiazine have also been explained below.

The optimal dosage of Sulphadiazine is largely dependent on the individual's body weight, medical history, gender and age. Besides the medical condition it is advised for, the route of administration also plays an important role in determining the correct drug dosage. Refer to the dosage section for a detailed discussion.

While these are the most often observed Sulphadiazine side effects, there are can be others also. These have been listed below. These side effects of Sulphadiazine are usually temporary and subside with the completion of treatment. If, however, they worsen or do not go away, please speak with your physician.

Sulphadiazine's effect during pregnancy is Moderate and Safe while nursing. Warnings related to Sulphadiazine's effects on the liver, heart and kidney, if any, have been listed below.

Besides this, Sulphadiazine may also have severe interaction with some medicines. See below for a complete list.

Along with the above-mentioned precautions, remember that taking Sulphadiazine is considered safe while driving, and is addictive.



Sulphadiazine Benefits & Uses

Sulphadiazine is used to treat the following -

Main Benefits

Other Benefits

Sulphadiazine Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult
  • Disease: Toxoplasmosis
  • Before or After Meal: Either
  • Single Maximum Dose: 1 g
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 6 hourly
  • Course Duration: As directed by the doctor
  • Special Instructions: first dose 200 mg orally once of Pyrimethamine then Sulfadiazine 1 g orally every 6 hours plus pyrimethamine 50 mg/day orally
Geriatric
  • Disease: Toxoplasmosis
  • Before or After Meal: Either
  • Single Maximum Dose: 1 g
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 1 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: first dose 200 mg orally once of Pyrimethamine then Sulfadiazine 1 g orally every 6 hours plus pyrimethamine 50 mg/day orally
13 - 18 years (Adolescent)
  • Disease: Toxoplasmosis
  • Before or After Meal: Either
  • Single Maximum Dose: 1 g
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 1 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: first dose 200 mg orally once of Pyrimethamine then Sulfadiazine 1 g orally every 6 hours plus pyrimethamine 50 mg/day orally
2 - 12 years (Child)
  • Disease: Toxoplasmosis
  • Before or After Meal: Either
  • Single Maximum Dose: 50 mg/kg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 1 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: first dose 2 mg/kg for 2 days orally of Pyrimethamine then Sulfadiazine 50 mg/kg 2 daily plus pyrimethamine 1 mg/kg/day


Sulphadiazine Side Effects

Based on research, the following side effects have been observed when Sulphadiazine is used -

Severe

  • Allergic reaction

Moderate

  • Hepatitis

Mild

Sulphadiazine Related Warnings

  • Is the use of Sulphadiazine safe for pregnant women?


    Sulphadiazine can cause unwanted side effects in pregnant women. If you experience any side effects, stop taking Sulphadiazine right away. Take your doctor's advice before taking it again.

    Moderate
  • Is the use of Sulphadiazine safe during breastfeeding?


    Breastfeeding women can safely use Sulphadiazine.

    Safe
  • What is the effect of Sulphadiazine on the Kidneys?


    Sulphadiazine is completely safe for kidneys.

    Safe
  • What is the effect of Sulphadiazine on the Liver?


    Using Sulphadiazine does not have any harmful effects on the liver.

    Safe
  • What is the effect of Sulphadiazine on the Heart?


    Sulphadiazine is completely safe for the heart.

    Safe


Severe Interaction of Sulphadiazine with Other Drugs

Sulphadiazine should not be taken with following medicines due to severe side effects it may cause to patients -

Severe



Frequently asked Questions about Sulphadiazine

  • Is this Sulphadiazine habit forming or addictive?


    No, you will not get addicted to Sulphadiazine.

    No
  • Is it safe to drive or operate heavy machinery when consuming?


    Yes, you can comfortably use machinery or drive after taking Sulphadiazine since it will not make you feel sleepy.

    Safe
  • Is it safe?


    Sulphadiazine is safe as it does not bear any side effects.

    Safe
  • Is it able to treat mental disorders?


    No, Sulphadiazine cannot treat any kind of mental disorder.

    No

Sulphadiazine Interactions with Food and Alcohol

  • Interaction between Food and Sulphadiazine


    Information is not available on the interaction of any foods with Sulphadiazine, due to a lack of research on this.

    Unknown
  • Interaction between Alcohol and Sulphadiazine


    Consuming limited amounts of alcohol while taking Sulphadiazine does not cause any harmful effects. But it is best to observe caution.

    Safe


See all substitutes for Sulphadiazine


This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience


References

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 705



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