Although it's believed that Calpol Tablet works mainly in the central nervous system (Brain and Spine). It prevents the release of prostaglandin, which is responsible for increasing pain and body temperature. It effectively reduces the intensity of pain signals to the brain.

Dr. Joydeep Sarkar MBBS , General Physician

You should take the minimum effective dose of Calpol Tablet that reduces body pain and fever. It should be used for the shortest time period till you get relief. Take it as per doctor's advice do not exceed dosage. Ideally, 1 or 2 tablets (500 mg) every four to six hours can be safely taken, do not take more than four doses in 24 hours. Please note paracetamol 500 mg tablet should not be given to children below 10 years until and unless prescribed by a child specialist.

Dr. Kuldeep Meena MBBS, MD , Pulmonology

No harmful interactions have been reported between Calpol Tablet and codeine. Do not take it until and unless prescribed. However, if you are experiencing any unpleasant medicinal side effects such as nausea, stomach pain, and tremors after taking Calpol Tablet. Inform your doctor immediately.

Dr. Kapil Sharma MBBS , General Physician

Yes, you can take Calpol Tablet with aspirin. No drug-drug interaction has been reported between them. But you're recommended to consult your doctor before taking these two medications together.

Calpol Tablet is being used by pregnant women for many years without any evident harmful effects on the baby. That's why it is usually recommended as the first-line painkiller for pregnant women. But it is not possible to say that this medicine is completely safe to use in pregnancy. You are highly recommended to check with your doctor/gynaecologist before taking any medicine even [medicine] during pregnancy.