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Cilastat is a prescription medicine that is available as a Injection. Secondary and off-label uses of Cilastat have also been mentioned below.
The optimal dosage of Cilastat is largely dependent on the individual's body weight, medical history, gender and age. The condition it has been prescribed for, and the route of administration also determine the right dosage. Detailed information has been provided in the dosage section.
While these are the most often observed Cilastat side effects, there are can be others also. These have been listed below. Usually, these side effects of Cilastat go away soon, and do not persist beyond the duration of the treatment. Consult your doctor if these side effects become worse or stay for a longer duration.
Furthermore, you should know that effect of Cilastat is Moderate for pregnant women and Moderate for women who are breastfeeding. In addition, Cilastat's effects on the liver, heart and kidney are discussed below in the Cilastat related warnings section.
Cilastat is not recommended if you suffer from certain medical conditions as it can have adverse effects. Kidney Disease, Kidney Disease are examples of such conditions. The section on Cilastat contraindications lists all such conditions.
Drug interactions for Cilastat have been reported in the medical literature. Refer to the list below for further details.
Along with the above-mentioned precautions, remember that taking Cilastat is considered safe while driving, and is addictive.
Cilastat is used to treat the following -
Other Benefits
This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.
Find the right dosage based on disease and age
| Age Group | Dosage |
| 13 - 18 years (Adolescent) |
|
| 2 - 12 years (Child) |
|
| Adult |
|
| Geriatric |
|
| Infant (1 month to 2 years) |
|
| Neonates (0 to 1 month) |
|
Based on research, the following side effects have been observed when Cilastat is used -
Severe
Moderate
Mild
Is the use of Cilastat safe for pregnant women?
Cilastat can have harmful effects in pregnant women. If you experience any discomfort after using Cilastat, then discontinue the use and take your doctor's advice.
Is the use of Cilastat safe during breastfeeding?
Breastfeeding women may feel side effects of Cilastat. If you see any side effects, stop taking Cilastat immediately and talk to your doctor. Take Cilastat again, only after your doctor's advice.
What is the effect of Cilastat on the Kidneys?
Kidney can be affected by Cilastat. If you experience any unwanted effects of this drug, stop taking it. You should take it again only after medical advice.
What is the effect of Cilastat on the Liver?
You may experience side effects on your liver after taking Cilastat. If this happens, then discontinue its use. Consult your medical practitioner, do as he/she suggests.
What is the effect of Cilastat on the Heart?
Side effects of Cilastat rarely affect the heart.
Cilastat should not be taken with following medicines due to severe side effects it may cause to patients -
Severe
Moderate
If you are suffering from any of the following diseases, you should not take Cilastat unless your doctor advises you to do so -
Is this Cilastat habit forming or addictive?
No, you will not get addicted to Cilastat.
Interaction between Food and Cilastat
Cilastat may take longer to act if you eat some foods while taking it. Follow your doctor's advice on this.
Interaction between Alcohol and Cilastat
Taking Cilastat with alcohol can have severely harmful effects on your health.
This medicine data has been created by -
References
US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Primaxin® (imipenem and cilastatin)
KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 731
April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 676-678
