Codine

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  • Manufactured by: Zydus Cadila
  • Contains / Salt: Codeine (10 mg) + Chlorpheniramine (4 mg)

Codine Information

Codine is a prescription drug, available for use as Syrup. It is typically used for the treatment of Allergic Rhinitis, Cough. Other than this, Codine has some other therapeutic uses, which have been discussed ahead.

The right dosage of Codine depends on the age, gender, and medical history of the patient. Individual symptoms and route of administration also determines the right dosage. For detailed information on this, read through the dosage section.

Common side effects of Codine include Nausea or vomiting, Abdominal Pain, Drowsiness. Normally, these side effects of Codine are not long lasting and go away when the treatment is finished. If, however, they worsen or do not go away, please speak with your physician.

Codine's effect during pregnancy is Moderate and Moderate while nursing. Further, the section on Codine related warnings talks about Codine's effects on the liver, heart and kidney.

Other contraindications of Codine have been discussed in the sections ahead.

Drug interactions for Codine have been reported in the medical literature. Refer to the list below for further details.

You should also be aware that Codine is not safe while driving, and is not addiction.

Codine Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult
  • Disease:
  • Before or After Meal: Either
  • Single Maximum Dose: 10 ml
  • Dosage Route: Oral
  • Frequency: 12 hourly
  • Course Duration: 7 days
  • Special Instructions: strength 4 mg chlorpheniramine and 20 mg codeine in 5 ml
Geriatric
  • Disease:
  • Before or After Meal: Either
  • Single Maximum Dose: 10 ml
  • Dosage Route: Oral
  • Frequency: 12 hourly
  • Course Duration: 7 days
  • Special Instructions: strength 4 mg chlorpheniramine and 20 mg codeine in 5 ml

Codine Side Effects

Based on research, the following side effects have been observed when Codine is used -

Common

Codine Related Warnings

  • Is the use of Codine safe for pregnant women?


    Codine may cause moderate side effects during pregnancy. If you feel its harmful effects, then stop taking this drug immediately, and do not take Codine again without your doctor's advice.

    Moderate
  • Is the use of Codine safe during breastfeeding?


    Women who are breastfeeding can experience some moderate side effects of Codine. Immediately discontinue Codine if you observe any side effects. Contact your doctor, and restart using it only if your doctor considers it safe for you.

    Moderate
  • What is the effect of Codine on the Kidneys?


    Codine may have mild side effects on the kidneys.

    Mild
  • What is the effect of Codine on the Liver?


    Side effects of Codine rarely affect the liver.

    Mild
  • What is the effect of Codine on the Heart?


    Codine has very mild side effects on the heart.

    Mild

Severe Interaction of Codine with Other Drugs

Codine should not be taken with following medicines due to severe side effects it may cause to patients -

Moderate


Codine Contraindications

If you are suffering from any of the following diseases, you should not take Codine unless your doctor advises you to do so -


Frequently asked Questions about Codine

  • Is this Codine habit forming or addictive?


    You may get addicted to Codine. Therefore, before taking it, consult your doctor.

    Yes
  • Is it safe to drive or operate heavy machinery when consuming?


    After taking Codine you may feel sleepy. So it is not advised to perform these activities.

    Dangerous
  • Is it safe?


    Codine should be used only after doctor's advice.

    Safe, but take only on Doctor's advise
  • Is it able to treat mental disorders?


    There is no benefit of taking Codine for mental disorders.

    No

Codine Interactions with Food and Alcohol

  • Interaction between Food and Codine


    It is safe to take Codine with food.

    Safe
  • Interaction between Alcohol and Codine


    Consuming Codine with alcohol can have many serious effects on your body.

    Severe

See all substitutes for Codine


This medicine data has been created by -

Vikas Chauhan
B.Pharma, Pharmacy
7 Years of Experience

References

Therapeutic Goods Administration (TGA): Department of Health [Internet]. Governmet of Australia; Package leaflet information for the user; Actacode ( codeine phosphate hemihydrate)

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 474

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 341-342

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 164,165

Package Leaflet [Internet]: TUXARIN ER™. USFDA

Package Leaflet [Internet]: CHLORPHENAMINE. Haupt Pharma Wülfing GmbH

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