Denosumab

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Denosumab Information



Denosumab Benefits & Uses

Denosumab is used to treat the following -

Other Benefits

Denosumab Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult
  • Disease: Osteoporosis
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 60 mg
  • Dosage Route: Parenteral
  • Frequency: doctor administered
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor
Geriatric
  • Disease: Osteoporosis
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 60 mg
  • Dosage Route: Parenteral
  • Frequency: doctor administered
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor
13 - 18 years (Adolescent)
  • Disease: Bone Cancer
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 120 mg
  • Dosage Route: Parenteral
  • Frequency: doctor administered
  • Course Duration: As directed by the doctor
  • Special Instructions: used in giant cell tumor of bone, patients above 13 years old and having weight above 45 kg can take

Denosumab Related Warnings

  • Is the use of Denosumab safe for pregnant women?


    Denosumab should not be taken during pregnancy, or should only be taken on the advice of a doctor as it may have severe side effects.

    Severe
  • Is the use of Denosumab safe during breastfeeding?


    Denosumab may cause serious side effects in breastfeeding women, so do not take this drug without doctor's advice.

    Severe
  • What is the effect of Denosumab on the Kidneys?


    Denosumab rarely affects the kidneys.

    Mild
  • What is the effect of Denosumab on the Liver?


    Using Denosumab does not have any harmful effects on the liver.

    Safe
  • What is the effect of Denosumab on the Heart?


    There are no any side effects of Denosumab for the heart.

    Safe


Severe Interaction of Denosumab with Other Drugs

Denosumab should not be taken with following medicines due to severe side effects it may cause to patients -

Moderate



Denosumab Contraindications

If you are suffering from any of the following diseases, you should not take Denosumab unless your doctor advises you to do so -



Frequently asked Questions about Denosumab

  • Is this Denosumab habit forming or addictive?


    Denosumab does not cause addiction.

    No
  • Is it safe to drive or operate heavy machinery when consuming?


    After taking Denosumab, you should not drive or work on any heavy machine, as Denosumab can make you drowsy.

    Dangerous
  • Is it safe?


    Yes, but take Denosumab only as per medical advice.

    Safe, but take only on Doctor's advise
  • Is it able to treat mental disorders?


    Denosumab is unable to treat or cure mental disorders.

    No

Denosumab Interactions with Food and Alcohol

  • Interaction between Food and Denosumab


    It is safe to take Denosumab with food.

    Safe
  • Interaction between Alcohol and Denosumab


    Information about the interaction of Denosumab and alcohol is not currently available because this topic has not been researched yet.

    Unknown


See all substitutes for Denosumab


This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience


References

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Xgeva (denosumab)

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 346

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 410-411



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