Mifepristone + Misoprostol

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Mifepristone + Misoprostol Information

Mifepristone + Misoprostol is a prescription medicine. Primarily, it is used for the treatment of Abortion.

Medical history of the patient along with age and gender determines the dosage of Mifepristone + Misoprostol. Besides the medical condition it is advised for, the route of administration also plays an important role in determining the correct drug dosage. Detailed information has been provided in the dosage section.

The side effects typically associated with Mifepristone + Misoprostol include Uterine Cramps, Nausea or vomiting, Diarrhoea. Apart from the aforementioned side effects, Mifepristone + Misoprostol can also lead to other problems, which have been listed below. Normally, these side effects of Mifepristone + Misoprostol are not long lasting and go away when the treatment is finished. However, if these continue for a longer time, consult your doctor right away.

Mifepristone + Misoprostol's effect during pregnancy is Severe and Moderate while nursing. In addition, Mifepristone + Misoprostol's effects on the liver, heart and kidney are discussed below in the Mifepristone + Misoprostol related warnings section.

Mifepristone + Misoprostol can cause adverse effects in certain medical conditions. It is strongly recommended to avoid Mifepristone + Misoprostol in conditions like Asthma, Porphyria.

Drug reaction of Mifepristone + Misoprostol with other medicines has been reported. A complete list of these interactions is given below.

Along with the above-mentioned precautions, remember that taking Mifepristone + Misoprostol is considered not safe while driving, and is not addictive.

  1. Mifepristone + Misoprostol Benefits & Uses
  2. Mifepristone + Misoprostol Dosage & How to Take
  3. Mifepristone + Misoprostol Side Effects
  4. Mifepristone + Misoprostol Related Warnings
  5. Severe Interaction of Mifepristone + Misoprostol with Other Drugs
  6. Mifepristone + Misoprostol Contraindications
  7. Frequently asked Questions about Mifepristone + Misoprostol
  8. Mifepristone + Misoprostol Interactions with Food and Alcohol

Mifepristone + Misoprostol Benefits & Uses

Mifepristone + Misoprostol is used to treat the following -

  1. Abortion Primary

Mifepristone + Misoprostol Dosage & How to Take

Find the right dosage based on disease and age

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Ingredients of Mifepristone + Misoprostol

Mifepristone
Misoprostol

Mifepristone + Misoprostol Side Effects

Based on research, the following side effects have been observed when Mifepristone + Misoprostol is used -

  1. Uterine Cramps
  2. Nausea or vomiting
  3. Diarrhoea
  4. Abdominal cramp
  5. Headache Rare
  6. Fever Severe
  7. Skin Infection
  8. Heavy Menstrual Periods
  9. Pain or discomfort
  10. Feeling Sick

Mifepristone + Misoprostol Related Warnings

Is the use of Mifepristone + Misoprostol safe for pregnant women?

Mifepristone + Misoprostol shows severe side effect on pregnant women. For this reason, pregnant women should only take it after taking medical advice.

Severe

Is the use of Mifepristone + Misoprostol safe during breastfeeding?

Women who are breastfeeding can experience some moderate side effects of Mifepristone + Misoprostol. Immediately discontinue Mifepristone + Misoprostol if you observe any side effects. Contact your doctor, and restart using it only if your doctor considers it safe for you.

Moderate

What is the effect of Mifepristone + Misoprostol on the Kidneys?

No research work has been carried out till date on effects of Mifepristone + Misoprostol on kidney. So it is not known whether taking Mifepristone + Misoprostol will cause side effects on kidney or not.

Unknown

What is the effect of Mifepristone + Misoprostol on the Liver?

Information about safety of Mifepristone + Misoprostol for the liver is not available since scientific research on this is yet to be done.

Unknown

What is the effect of Mifepristone + Misoprostol on the Heart?

In the absence of any scientific study on the side effects of Mifepristone + Misoprostol on the heart, information on safety of Mifepristone + Misoprostol for the heart is unavailable.

Unknown

Severe Interaction of Mifepristone + Misoprostol with Other Drugs

Mifepristone + Misoprostol should not be taken with following medicines due to severe side effects it may cause to patients -

Mifepristone + Misoprostol Contraindications

If you are suffering from any of the following diseases, you should not take Mifepristone + Misoprostol unless your doctor advises you to do so -

  1. Asthma
  2. Porphyria

Frequently asked Questions about Mifepristone + Misoprostol

Is this Mifepristone + Misoprostol habit forming or addictive?

No, there is no any evidence that Mifepristone + Misoprostol is addictive.

No

Is it safe to drive or operate heavy machinery when consuming?

After taking Mifepristone + Misoprostol you may feel sleepy. So it is not advised to perform these activities.

Dangerous

Is it safe?

Yes, but take Mifepristone + Misoprostol only as per medical advice.

Safe, but take only on Doctor's advise

Is it able to treat mental disorders?

No, Mifepristone + Misoprostol is not used to treat mental disorders.

No

Mifepristone + Misoprostol Interactions with Food and Alcohol

Interaction between Food and Mifepristone + Misoprostol

Taking Mifepristone + Misoprostol with food can show serious side effects. Consult the doctor to avoid this.

Severe

Interaction between Alcohol and Mifepristone + Misoprostol

No research has been done on this till date. Therefore, it is not known what the effect of taking Mifepristone + Misoprostol with alcohol will be.

Unknown

Mifepristone + Misoprostol FAQs

Question over 1 year ago

Can I take Mifepristone + Misoprostol on empty stomach?

Yes, you can take Mifepristone + Misoprostol on empty stomach. It does not irritate the stomach lining if taken in an empty stomach. However, it is best to consult your doctor 

Question almost 2 years ago

What are the symptoms of Mifepristone + Misoprostol overdose?

Dr. Ayush Pandey MBBS , General Physician

Mifepristone + Misoprostol overdose, should be observed closely for signs of adrenal failure, trouble breathing. Symptoms of overdose may include: severe vaginal bleeding, Nausea, vomiting, diarrhea, weakness, or dizziness may occur.

Question almost 2 years ago

Can I take Mifepristone + Misoprostol without consulting a doctor?

Dr. Vedprakash Verma MBBS , General Physician

Mifepristone + Misoprostol is a prescription drug so do not take it without consulting a doctor. It can be harmful to take this medicine if you actually don't require it.

Question almost 2 years ago

How does Mifepristone + Misoprostol work?

Dr. K. M. Bhatt MBBS, PG Dip , General Physician

Mifepristone + Misoprostol blocks the action of progesterone hormone which is responsible for maintaining the pregnancy. Progesterone prepares the uterus to receive and sustain the fertilized egg and is an important hormone for sustaining a pregnancy. It also terminates early pregnancy by blocking the activity of progesterone and progesterone receptors. Additionally, it also stimulates the contraction of the uterus.

Question over 1 year ago

Can I take Mifepristone + Misoprostol and misoprostol at the same time?

Dr. Joydeep Sarkar MBBS , General Physician

No, Mifepristone + Misoprostol and misoprostol can't be taken at the same time, because it will be less effective if taken at the same time. You should always take 24 to 48 hours apart or consult your doctor regarding the exact gap between these two medicines.

This medicine data has been created by -
Vikas Chauhan
B.Pharma, Pharmacy
3 Years of Experience

References

  1. April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 858-859
  2. KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 319-320
  3. US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Mifeprex® (mifepristone)
  4. April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 867
  5. KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 654
  6. US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Cytotec® (misoprostol)
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