Pazomet 15/500 Tablet

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10 Tablet in 1 Strip
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Pazomet 15/500 Tablet Information

Pazomet 15/500 Tablet, a prescription drug, is manufactured in various forms such as Tablet. Other than this, Pazomet 15/500 Tablet has some other therapeutic uses, which have been discussed ahead.

The optimal dosage of Pazomet 15/500 Tablet is largely dependent on the individual's body weight, medical history, gender and age. Besides the medical condition it is advised for, the route of administration also plays an important role in determining the correct drug dosage. This information has been provided in detail in the dosage section.

The most common side effects of Pazomet 15/500 Tablet are Stomach Upset, Difficulty urinating, Muscle Ache. Apart from the aforementioned side effects, Pazomet 15/500 Tablet can also lead to other problems, which have been listed below. Normally, these side effects of Pazomet 15/500 Tablet are not long lasting and go away when the treatment is finished. Consult your doctor if these side effects become worse or stay for a longer duration.

It is also important to note that Pazomet 15/500 Tablet has a Moderate effect for pregnant women and Moderate effect on lactating mothers. In addition, Pazomet 15/500 Tablet's effects on the liver, heart and kidney are discussed below in the Pazomet 15/500 Tablet related warnings section.

Pazomet 15/500 Tablet is contraindicated in people with pre-existing medical conditions like Congestive Heart Failure (CHF), Anemia, Shock as it can result in adverse effects. Some other conditions that can be affected by Pazomet 15/500 Tablet are listed in the contraindications section below.

Drug reaction of Pazomet 15/500 Tablet with other medicines has been reported. A complete list of these interactions is given below.

Along with the above-mentioned precautions, remember that taking Pazomet 15/500 Tablet is considered safe while driving, and is addictive.



Pazomet 15/500 Tablet Benefits & Uses

Pazomet 15/500 Tablet is used to treat the following -

Other Benefits

  • Diabetes Type 2

Pazomet 15/500 Tablet Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult
  • Disease: Diabetes Type 2
  • Before or After Meal: With meal
  • Single Maximum Dose: 515 mg
  • Dosage Form: Tablet (Immediate Release)
  • Dosage Route: Oral
  • Frequency: 2 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: strength 15 mg pioglitazone and 500 mg metformin
Geriatric
  • Disease: Diabetes Type 2
  • Before or After Meal: With meal
  • Single Maximum Dose: 865 mg
  • Dosage Form: Tablet (Immediate Release)
  • Dosage Route: Oral
  • Frequency: 1 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: strength 15 mg pioglitazone and 850 mg metformin

Pazomet 15/500 Tablet Related Warnings

  • Is the use of Pazomet 15/500 Tablet safe for pregnant women?


    Pazomet can cause unwanted side effects in pregnant women. If you experience any side effects, stop taking Pazomet right away. Take your doctor's advice before taking it again.

  • Is the use of Pazomet 15/500 Tablet safe during breastfeeding?


    Women who are breastfeeding can experience some moderate side effects of Pazomet. Immediately discontinue Pazomet if you observe any side effects. Contact your doctor, and restart using it only if your doctor considers it safe for you.

  • What is the effect of Pazomet 15/500 Tablet on the Kidneys?


    Very few cases of side effects of Pazomet on kidney have been reported.

  • What is the effect of Pazomet 15/500 Tablet on the Liver?


    You may experience side effects on your liver after taking Pazomet. If this happens, then discontinue its use. Consult your medical practitioner, do as he/she suggests.

  • What is the effect of Pazomet 15/500 Tablet on the Heart?


    You may experience side effects on your heart after taking Pazomet. If this happens, then discontinue its use. Consult your medical practitioner, and do as he/she suggests.



Pazomet 15/500 Tablet Contraindications

If you are suffering from any of the following diseases, you should not take Pazomet 15/500 Tablet unless your doctor advises you to do so -



Frequently asked Questions about Pazomet 15/500 Tablet

  • Is this Pazomet 15/500 Tablet habit forming or addictive?


    No, there is no any evidence that Pazomet 15/500 Tablet is addictive.

Pazomet 15/500 Tablet Interactions with Food and Alcohol

  • Interaction between Food and Pazomet 15/500 Tablet


    Due to a lack of research, nothing can be said about the consequences of taking Pazomet 15/500 Tablet together with food.

  • Interaction between Alcohol and Pazomet 15/500 Tablet


    Taking [medicine] and alcohol at the same time may lead to mild side effects. Contact your doctor right away if you observe any side effects.



Frequently asked Questions about Pazomet 15/500 Tablet

Question over 4 years ago

Can Pazomet cause alopecia (hair loss)?

Dr. Vipin Khadse MBBS , General Physician

Pazomet is not a known cause of alopecia (hair loss). However, the conditions treated by Pazomet type 2 diabetes and PCOS, often list hair loss as a possible symptom.

Question almost 5 years ago

What are the long term effects of Pazomet?

Dr. Bharat MBBS , General Physician

The long-term use can lead to the deficiency of Vitamin B12, which can further lead to megaloblastic anemia. Furthermore, Long-term Metformin use can also lead to kidney and liver problems. 

Question over 4 years ago

How does Pazomet increase lactic acidosis?

Dr. Manoj Meena MBBS , General Physician

Lactic acidosis associated with Pazomet treatment is a rare but fatal adverse effect. Lactic acidosis appears to result from biguanide interference causing an increase in production and decrease in clearance of lactate leading to higher cellular lactate levels. A decrease in pyruvate carboxylase activity, the rate-limiting enzyme in the formation of glucose from lactate, can also decrease hepatic metabolism of lactate. leading to increasing lactic acidosis. Signs and symptoms of Pazomet induced lactic acidosis are nonspecific and include anorexia, nausea, vomiting, altered level of consciousness, hyperpnoea, abdominal pain, and thirst. 

Question over 4 years ago

Can I take Pazomet with a beta-blocker?

Dr. Sameer Awadhiya MBBS , Pediatrics

Yes, you can take Pazomet with a beta-blocker. People with diabetes tend to develop heart disease or stroke at an earlier age than the general population. One reason for this is that high glucose levels increase your risk of high blood pressure (hypertension). No harmful interactions are seen between them. However, a recent study suggests that beta-blockers can decrease the plasma level of Pazomet and long-term use can increase lactic acid and uric acid in the blood.

Question over 4 years ago

How does Pazomet work for PCOS?

Dr. Sameer Awadhiya MBBS , Pediatrics

Pazomet increases the sensitivity of insulin, young women with PCOS often have elevated insulin levels and are more likely to develop diabetes. It is often prescribed for women with PCOS to help prevent diabetes. A lifestyle that includes healthy nutrition and daily exercise is the most important part of a PCOS treatment plan.



See all substitutes for Pazomet



This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience



References

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Glucophage® (metformin hydrochloride)

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 275-276

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 825-826

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Actos (pioglitazone hydrochloride)

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 276-277

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 1032-1033

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