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Zilenta M is a prescription medicine that is available as a Tablet. Other than this, Zilenta M has some other therapeutic uses, which have been discussed ahead.
The correct dosage of Zilenta M depends on the patient's age, gender, and medical history. Individual symptoms and route of administration also determines the right dosage. Detailed information has been provided in the dosage section.
Common side effects of Zilenta M include Stomach Upset, Difficulty urinating, Hypoglycemia (Low blood sugar level). Besides the aforementioned side effects, there are other adverse effects of Zilenta M as well, which are listed below. These side effects of Zilenta M are usually temporary and subside with the completion of treatment. Consult your doctor if these side effects become worse or stay for a longer duration.
In addition, Zilenta M's effect is Moderate during pregnancy and Severe for lactating mothers. Further, the section on Zilenta M related warnings talks about Zilenta M's effects on the liver, heart and kidney.
Zilenta M is contraindicated in people with pre-existing medical conditions like Congestive Heart Failure (CHF), Anemia, Shock as it can result in adverse effects. Some other conditions that can be affected by Zilenta M are listed in the contraindications section below.
Drug interactions for Zilenta M have been reported in the medical literature. See below for a complete list.
In addition to the above precautions for Zilenta M, it is important to know that it is safe while driving, and is habit-forming.
Zilenta M is used to treat the following -
Other Benefits
This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.
Find the right dosage based on disease and age
Age Group | Dosage |
13 - 18 years (Adolescent) |
|
Adult |
|
Geriatric |
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Is the use of Zilenta M safe for pregnant women?
Zilenta M can cause unwanted side effects in pregnant women. If you experience any side effects, stop taking Zilenta M right away. Take your doctor's advice before taking it again.
Is the use of Zilenta M safe during breastfeeding?
Women who are breastfeeding may experience severe harmful effects after taking Zilenta M. It should only be taken after medical advice.
What is the effect of Zilenta M on the Kidneys?
Information about safety of Zilenta M for kidney is not available since scientific research on this topic is yet to be done.
What is the effect of Zilenta M on the Liver?
So far, no research has been carried out on the effects of Zilenta M on the liver. So it is not known whether taking Zilenta M will affect the liver or not.
What is the effect of Zilenta M on the Heart?
Information about safety of Zilenta M for heart is not available since scientific research on this is yet to be done.
Zilenta M should not be taken with following medicines due to severe side effects it may cause to patients -
Severe
Moderate
If you are suffering from any of the following diseases, you should not take Zilenta M unless your doctor advises you to do so -
Is this Zilenta M habit forming or addictive?
No, you will not get addicted to Zilenta M.
Interaction between Food and Zilenta M
There is no information on the effects of taking Zilenta M with food, because this topic has not been scientifically researched yet.
Interaction between Alcohol and Zilenta M
It is difficult to say anything about the effect of Zilenta M and alcohol. No research has been done on this yet.
Yes, you can take Zilenta M with a beta-blocker. People with diabetes tend to develop heart disease or stroke at an earlier age than the general population. One reason for this is that high glucose levels increase your risk of high blood pressure (hypertension). No harmful interactions are seen between them. However, a recent study suggests that beta-blockers can decrease the plasma level of Zilenta M and long-term use can increase lactic acid and uric acid in the blood.
Yes, Zilenta M can be taken with the statin. There is no serious or harmful interaction have been observed between them. Some studies say that it's possible your blood sugar (blood glucose) level may increase when you take a statin, which may lead to developing type 2 diabetes. The risk is small but important enough that the Food and Drug Administration (FDA) has issued a warning on statin labels regarding blood glucose levels and diabetes.
Yes, you can take Zilenta M with gliclazide, no harmful interactions have been reported between them. However, it is not necessary that no interaction can happen between these two. But before taking such kind of combination you must consult your doctor.
Zilenta M helps in weight loss by reducing appetite and food intake. It also increases the insulin sensitivity in your body to work more effectively. This lead to decreased glucose production increases the use of glucose and decrease the fat deposition further helps in weight loss. However, Zilenta M is not approved for weight loss, this is an off-label use.
Lactic acidosis associated with Zilenta M treatment is a rare but fatal adverse effect. Lactic acidosis appears to result from biguanide interference causing an increase in production and decrease in clearance of lactate leading to higher cellular lactate levels. A decrease in pyruvate carboxylase activity, the rate-limiting enzyme in the formation of glucose from lactate, can also decrease hepatic metabolism of lactate. leading to increasing lactic acidosis. Signs and symptoms of Zilenta M induced lactic acidosis are nonspecific and include anorexia, nausea, vomiting, altered level of consciousness, hyperpnoea, abdominal pain, and thirst.
This medicine data has been created by -
B.Pharma, Pharmacy
5 Years of Experience
References
US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Glucophage® (metformin hydrochloride)
KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 275-276
April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 825-826