Metsafe 1000 Tablet SR

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10 Tablet in 1 Strip
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Metsafe 1000 Tablet SR Information

Metsafe 1000 Tablet SR, a prescription drug, is manufactured in various forms such as Tablet. It is primarily used for the treatment of Diabetes.

The correct dosage of Metsafe 1000 Tablet SR depends on the patient's age, gender, and medical history. The condition it has been prescribed for, and the route of administration also determine the right dosage. Detailed information has been provided in the dosage section.

Metsafe 1000 Tablet SR also has some side effects, the most common being Stomach Upset, Difficulty urinating. Besides the aforementioned side effects, there are other adverse effects of Metsafe 1000 Tablet SR as well, which are listed below. Normally, these side effects of Metsafe 1000 Tablet SR are not long lasting and go away when the treatment is finished. If, however, they worsen or do not go away, please speak with your physician.

Metsafe 1000 Tablet SR's effect during pregnancy is Mild and Moderate while nursing. It is important to know if Metsafe 1000 Tablet SR has any effect on the kidney, liver and heart. Information on such adverse effects, if any, has been given in the Metsafe 1000 Tablet SR related warnings section.

Individuals suffering from medical conditions like Congestive Heart Failure (CHF), Anemia, Shock must refrain from the use of Metsafe 1000 Tablet SR since this can cause severe adverse effects. The section on Metsafe 1000 Tablet SR contraindications lists all such conditions.

Drug interactions for Metsafe 1000 Tablet SR have been reported in the medical literature. A complete list of these interactions is given below.

In addition to these precautions, you may also note that Metsafe 1000 Tablet SR is safe while driving, and is is addictive in nature.



Metsafe 1000 Tablet SR Benefits & Uses

Metsafe 1000 Tablet SR is used to treat the following -

Main Benefits

Metsafe 1000 Tablet SR Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult
  • Disease: Diabetes Type 2
  • Before or After Meal: With meal
  • Single Maximum Dose: 500 mg
  • Dosage Form: Tablet (Immediate Release)
  • Dosage Route: Oral
  • Frequency: 2 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor
Geriatric
  • Disease: Diabetes Type 2
  • Before or After Meal: With meal
  • Single Maximum Dose: 500 mg
  • Dosage Form: Tablet (Immediate Release)
  • Dosage Route: Oral
  • Frequency: 2 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor
13 - 18 years (Adolescent)
  • Disease: Diabetes Type 2
  • Before or After Meal: With meal
  • Single Maximum Dose: 500 mg
  • Dosage Form: Tablet (Immediate Release)
  • Dosage Route: Oral
  • Frequency: 2 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor
2 - 12 years (Child)
  • Disease: Diabetes Type 2
  • Before or After Meal: With meal
  • Single Maximum Dose: 500 mg
  • Dosage Form: Tablet (Immediate Release)
  • Dosage Route: Oral
  • Frequency: 2 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor

Metsafe 1000 Tablet SR Related Warnings

  • Is the use of Metsafe 1000 Tablet SR safe for pregnant women?


    Metsafe has mild to no side effects in pregnant women.

    Mild
  • Is the use of Metsafe 1000 Tablet SR safe during breastfeeding?


    Breastfeeding women may feel side effects of Metsafe. If you see any side effects, stop taking Metsafe immediately and talk to your doctor. Take Metsafe again, only after your doctor's advice.

    Moderate
  • What is the effect of Metsafe 1000 Tablet SR on the Kidneys?


    Metsafe does not damage the kidneys.

    Safe
  • What is the effect of Metsafe 1000 Tablet SR on the Liver?


    Metsafe is not harmful for the liver.

    Safe
  • What is the effect of Metsafe 1000 Tablet SR on the Heart?


    You can take Metsafe without any fear of damage to the heart.

    Safe


Metsafe 1000 Tablet SR Contraindications

If you are suffering from any of the following diseases, you should not take Metsafe 1000 Tablet SR unless your doctor advises you to do so -



Frequently asked Questions about Metsafe 1000 Tablet SR

  • Is this Metsafe 1000 Tablet SR habit forming or addictive?


    Metsafe 1000 Tablet SR does not cause addiction.

    No
  • Is it safe to drive or operate heavy machinery when consuming?


    Yes, you can comfortably use machinery or drive after taking Metsafe 1000 Tablet SR since it will not make you feel sleepy.

    Safe
  • Is it safe?


    Metsafe 1000 Tablet SR should be used only after doctor's advice.

    Safe, but take only on Doctor's advise
  • Is it able to treat mental disorders?


    No, Metsafe 1000 Tablet SR cannot treat any kind of mental disorder.

    No

Metsafe 1000 Tablet SR Interactions with Food and Alcohol

  • Interaction between Food and Metsafe 1000 Tablet SR


    There is no information on the effects of taking Metsafe 1000 Tablet SR with food, because this topic has not been scientifically researched yet.

    Unknown
  • Interaction between Alcohol and Metsafe 1000 Tablet SR


    Consult your doctor before consuming alcohol while taking Metsafe 1000 Tablet SR as it can have severe side effects.

    Severe


Frequently asked Questions about Metsafe 1000 Tablet SR

Question almost 5 years ago

Does Metsafe cause sweating?

Dr. Joydeep Sarkar MBBS , Internal Medicine

Yes, Metsafe can cause night sweat, the exact mechanism of sweating is not known. But some research suggests that Metsafe causes hypoglycemia (low blood sugar) especially at night which can cause night sweats. Need to monitor your blood glucose level regularly, and talk to your doctor as your dose of Metsafe may need to be adjusted.

Question about 5 years ago

How long should I take Metsafe for?

Dr. Ram Saini MD, MBBS , General Physician

Metsafe can be taken forever, diabetes is a progressive disease it's possible that more medication and/or insulin may eventually need to be added to the regime. 

Question over 4 years ago

How does Metsafe increase lactic acidosis?

Dr. Manoj Meena MBBS , General Physician

Lactic acidosis associated with Metsafe treatment is a rare but fatal adverse effect. Lactic acidosis appears to result from biguanide interference causing an increase in production and decrease in clearance of lactate leading to higher cellular lactate levels. A decrease in pyruvate carboxylase activity, the rate-limiting enzyme in the formation of glucose from lactate, can also decrease hepatic metabolism of lactate. leading to increasing lactic acidosis. Signs and symptoms of Metsafe induced lactic acidosis are nonspecific and include anorexia, nausea, vomiting, altered level of consciousness, hyperpnoea, abdominal pain, and thirst. 

Question over 5 years ago

How does Metsafe work?

Dr. Rahul Poddar MBBS, DNB, MBBS, DNB , General Surgery

Metsafe works by decreasing the hepatic glucose production. It also works to lower blood sugar by increasing your sensitivity to insulin and decreasing the amount of glucose that is absorbed from the food you eat.

Question almost 5 years ago

Does Metsafe cause stomach ulcers?

Dr. Mayank Yadav MBBS , General Physician

Yes, Metsafe commonly cause stomach upset like diarrhea, abdominal pain, nausea, and vomiting. To avoid these side effects you should take Metsafe with your meal and increase the dose gradually.



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This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience



References

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Glucophage® (metformin hydrochloride)

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 275-276

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 825-826

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