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Amifostine

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Amifostine Information

  1. Amifostine Benefits & Uses
  2. Amifostine Dosage & How to Take
  3. Amifostine Side Effects
  4. Amifostine Related Warnings
  5. Severe Interaction of Amifostine with Other Drugs
  6. Amifostine Contraindications
  7. Frequently asked Questions about Amifostine
  8. Amifostine Interactions with Food and Alcohol

Amifostine Benefits & Uses

Amifostine is used to treat the following -

  1. Dry Mouth Primary
  2. Chronic Kidney Disease

Amifostine Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

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Ingredients of Amifostine

Amifostine

Amifostine Side Effects

Based on research, the following side effects have been observed when Amifostine is used -

  1. Nausea or vomiting
  2. Chills
  3. Tremor
  4. Drowsiness
  5. Fever Mild
  6. Flushing
  7. Fatigue Mild
  8. Headache Mild
  9. Hiccup
  10. Sneezing

Amifostine Related Warnings

Is the use of Amifostine safe for pregnant women?

It is not known what effect Amifostine will have on pregnant women, because no research work has been carried out on this till date.

Unknown

Is the use of Amifostine safe during breastfeeding?

No research work has been carried out till date on effect of Amifostine on breastfeeding women. So it is not known whether taking Amifostine will cause side effects or not.

Unknown

What is the effect of Amifostine on the Kidneys?

Amifostine has very mild side effects on the kidneys.

Mild

What is the effect of Amifostine on the Liver?

Amifostine is not harmful for the liver.

Safe

What is the effect of Amifostine on the Heart?

Side effects of Amifostine rarely affect the heart.

Mild

Severe Interaction of Amifostine with Other Drugs

Amifostine should not be taken with following medicines due to severe side effects it may cause to patients -

Amifostine Contraindications

If you are suffering from any of the following diseases, you should not take Amifostine unless your doctor advises you to do so -

  1. Calcium Deficiency
  2. Low Blood Pressure (Hypotension)
  3. Heart Failure
  4. Stroke
  5. Dehydration

Frequently asked Questions about Amifostine

Is this Amifostine habit forming or addictive?

No, there is no any evidence that Amifostine is addictive.

No

Is it safe to drive or operate heavy machinery when consuming?

After taking Amifostine you may feel sleepy. So it is not advised to perform these activities.

Dangerous

Is it safe?

Yes, but take Amifostine only as per medical advice.

Safe, but take only on Doctor's advise

Is it able to treat mental disorders?

No, Amifostine is not used to treat mental disorders.

No

Amifostine Interactions with Food and Alcohol

Interaction between Food and Amifostine

Eating certain foods may increase the time it takes Amifostine to have an effect. You should consult your doctor about it.

Mild

Interaction between Alcohol and Amifostine

Side effects of drinking alcohol and taking Amifostine at the same time are rare and minor. However, if you face any side effects, talk to your doctor immediately.

Mild
This medicine data has been created by -
Dr. Md Saadullah
M.Pharma, Pharmacy
3 Years of Experience
View Doctor Profile
Dr. Vikas Chauhan
B.Pharma, Pharmacy
2 Years of Experience
View Doctor Profile

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References

  1. US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Ethyol® (amifostine)
  2. KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 876
  3. April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 133-134