Buprenorphine

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Buprenorphine Information

Buprenorphine is a prescription medicine. Pain, Opioid Toxicity are some of its major therapeutic uses. The alternative uses of Buprenorphine have also been explained below.

The correct dosage of Buprenorphine depends on the patient's age, gender, and medical history. The condition it has been prescribed for, and the route of administration also determine the right dosage. Refer to the dosage section for a detailed discussion.

Apart from the aforementioned side effects, Buprenorphine can also lead to other problems, which have been listed below. Normally, these side effects of Buprenorphine are not long lasting and go away when the treatment is finished. Consult your doctor if these side effects become worse or stay for a longer duration.

It is also important to note that Buprenorphine has a Moderate effect for pregnant women and Severe effect on lactating mothers. Further, the section on Buprenorphine related warnings talks about Buprenorphine's effects on the liver, heart and kidney.

Buprenorphine can cause adverse effects in certain medical conditions. It is strongly recommended to avoid Buprenorphine in conditions like Liver Disease, Asthma, COPD (Chronic Obstructive Pulmonary Disease). Other conditions have been mentioned below in the Buprenorphine contraindications section.

Drug interactions for Buprenorphine have been reported in the medical literature. See below for a complete list.

You should also be aware that Buprenorphine is not safe while driving, and is not addiction.



Buprenorphine Benefits & Uses

Buprenorphine is used to treat the following -

Main Benefits

Other Benefits

Buprenorphine Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult
  • Disease: Opioid Toxicity
  • Before or After Meal: After Meal
  • Single Maximum Dose: 16 mg
  • Dosage Route: Oral
  • Frequency: 1 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor
Geriatric
  • Disease: Opioid Toxicity
  • Before or After Meal: After Meal
  • Single Maximum Dose: 16 mg
  • Dosage Route: Oral
  • Frequency: 1 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor

Buprenorphine Related Warnings

  • Is the use of Buprenorphine safe for pregnant women?


    Pregnant women may experience moderate side effects from Buprenorphine. It is best to stop taking Buprenorphine immediately and inform your doctor if you notice any discomfort.

    Moderate
  • Is the use of Buprenorphine safe during breastfeeding?


    Buprenorphine should not be taken without taking your doctor's advice, as it may have severe side effects on breastfeeding women.

    Severe
  • What is the effect of Buprenorphine on the Kidneys?


    Buprenorphine is not harmful for kidneys.

    Safe
  • What is the effect of Buprenorphine on the Liver?


    Buprenorphine may have mild side effects on the liver. Most people will never see any effect on the liver.

    Mild
  • What is the effect of Buprenorphine on the Heart?


    Buprenorphine is rarely harmful for the heart.

    Mild


Severe Interaction of Buprenorphine with Other Drugs

Buprenorphine should not be taken with following medicines due to severe side effects it may cause to patients -

Severe

Moderate



Buprenorphine Contraindications

If you are suffering from any of the following diseases, you should not take Buprenorphine unless your doctor advises you to do so -



Frequently asked Questions about Buprenorphine

  • Is this Buprenorphine habit forming or addictive?


    Yes, Buprenorphine can get addictive. Consume it only after doctor's advise.

    Yes
  • Is it safe to drive or operate heavy machinery when consuming?


    After taking Buprenorphine you may feel sleepy. So it is not advised to perform these activities.

    Dangerous
  • Is it safe?


    Buprenorphine should be used only after doctor's advice.

    Safe, but take only on Doctor's advise
  • Is it able to treat mental disorders?


    There is no benefit of taking Buprenorphine for mental disorders.

    No

Buprenorphine Interactions with Food and Alcohol

  • Interaction between Food and Buprenorphine


    Taking Buprenorphine with food does not harm your health.

    Safe
  • Interaction between Alcohol and Buprenorphine


    Taking Buprenorphine with alcohol can have severely harmful effects on your health.

    Severe


See all substitutes for Buprenorphine


This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience


References

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 482

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Subutex (buprenorphine)

Therapeutic Goods Administration (TGA): Department of Health [Internet]. Governmet of Australia; Package leaflet information for the user; Bupredermal® (buprenorphine)

Therapeutic Goods Administration (TGA): Department of Health [Internet]. Governmet of Australia; Package leaflet information for the user; Bupredermal® (buprenorphine)

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