Digoxin

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Digoxin Information

Digoxin is a prescription drug, available for use as Injection,Tablet,Liquid. Primarily, it is used for the treatment of Heart Failure, Arrhythmia. Digoxin also has some secondary and off-label uses. These are listed below.

The right dosage of Digoxin depends on the age, gender, and medical history of the patient. Individual symptoms and route of administration also determines the right dosage. Refer to the dosage section for a detailed discussion.

Apart from the aforementioned side effects, Digoxin can also lead to other problems, which have been listed below. Usually, these side effects of Digoxin go away soon, and do not persist beyond the duration of the treatment. If, however, they worsen or do not go away, please speak with your physician.

In addition, Digoxin's effect is Severe during pregnancy and Safe for lactating mothers. Further, the section on Digoxin related warnings talks about Digoxin's effects on the liver, heart and kidney.

Individuals suffering from medical conditions like Bradycardia (Slow Heart Rate), Hypercalcemia must refrain from the use of Digoxin since this can cause severe adverse effects. Other contraindications of Digoxin have been discussed in the sections ahead.

Besides this, Digoxin may also have severe interaction with some medicines. Refer to the list below for further details.

Along with the above-mentioned precautions, remember that taking Digoxin is considered not safe while driving, and is not addictive.


Digoxin Benefits & Uses

Digoxin is used to treat the following -

Main Benefits

Other Benefits

Digoxin Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult
  • Disease:
  • Before or After Meal: Either
  • Single Maximum Dose: 0.25 mg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 2 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: For course duration follow doctor's advice, dose may rarely increase 0.375-0.5 mg/day
Geriatric
  • Disease:
  • Before or After Meal: Either
  • Single Maximum Dose: 0.25 mg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 2 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: For course duration follow doctor's advice, dose may rarely increase 0.375-0.5 mg/day
13 - 18 years (Adolescent)
  • Disease:
  • Before or After Meal: Either
  • Single Maximum Dose: 5 mcg/kg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 2 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: For course duration follow doctor's advice
2 - 12 years (Child)
  • Disease:
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 5 mcg/kg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 2 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: For course duration follow doctor's advice, Initially given 17.5 mcg/kg for 3 dose

Digoxin Side Effects

Based on research, the following side effects have been observed when Digoxin is used -

Severe

Mild

Digoxin Related Warnings

  • Is the use of Digoxin safe for pregnant women?


    Digoxin has many dangerous side effects in pregnant women. If you are pregnant, do not consume Digoxin without medical advice.

    Severe
  • Is the use of Digoxin safe during breastfeeding?


    Digoxin is safe for breastfeeding women.

    Safe
  • What is the effect of Digoxin on the Kidneys?


    Digoxin has very mild side effects on the kidneys.

    Mild
  • What is the effect of Digoxin on the Liver?


    Information about safety of Digoxin for the liver is not available since scientific research on this is yet to be done.

    Unknown
  • What is the effect of Digoxin on the Heart?


    Very few cases of side effects of Digoxin on the heart have been reported.

    Mild

Severe Interaction of Digoxin with Other Drugs

Digoxin should not be taken with following medicines due to severe side effects it may cause to patients -

Severe

Moderate


Digoxin Contraindications

If you are suffering from any of the following diseases, you should not take Digoxin unless your doctor advises you to do so -


Frequently asked Questions about Digoxin

  • Is this Digoxin habit forming or addictive?


    Forming a habit of Digoxin has not been reported.

    No
  • Is it safe to drive or operate heavy machinery when consuming?


    After taking Digoxin you may feel sleepy. So it is not advised to perform these activities.

    Dangerous
  • Is it safe?


    Yes, Digoxin is safe but you must consult your doctor before taking it.

    Safe, but take only on Doctor's advise
  • Is it able to treat mental disorders?


    No, the use of Digoxin in mental disorders is not effective.

    No

Digoxin Interactions with Food and Alcohol

  • Interaction between Food and Digoxin


    Taking Digoxin with food does not cause any problems.

    Safe
  • Interaction between Alcohol and Digoxin


    No research has been done on this till date. Therefore, it is not known what the effect of taking Digoxin with alcohol will be.

    Unknown

See all substitutes for Digoxin


This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
7 Years of Experience


References

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 430-433

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 512-519

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Lanoxin® (digoxin)

Therapeutic Goods Administration (TGA): Department of Health [Internet]. Governmet of Australia; Package leaflet information for the user; Sigmaxin (digoxin)

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 430-433

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 512-519

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Lanoxin® (digoxin)

Therapeutic Goods Administration (TGA): Department of Health [Internet]. Governmet of Australia; Package leaflet information for the user; Sigmaxin (digoxin)

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 430-433

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 512-519

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Lanoxin® (digoxin)

Therapeutic Goods Administration (TGA): Department of Health [Internet]. Governmet of Australia; Package leaflet information for the user; Sigmaxin (digoxin)

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 430-433

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 512-519

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Lanoxin® (digoxin)

Therapeutic Goods Administration (TGA): Department of Health [Internet]. Governmet of Australia; Package leaflet information for the user; Sigmaxin (digoxin)

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