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Glyciphage SR 850 Tablet is a commercial drug that is prescribed in the form of Tablet. It is primarily used for the treatment of Diabetes.
The optimal dosage of Glyciphage SR 850 Tablet is largely dependent on the individual's body weight, medical history, gender and age. Individual symptoms and route of administration also determines the right dosage. Detailed information has been provided in the dosage section.
The side effects typically associated with Glyciphage SR 850 Tablet include Stomach Upset, Difficulty urinating. Besides the aforementioned side effects, there are other adverse effects of Glyciphage SR 850 Tablet as well, which are listed below. These side effects of Glyciphage SR 850 Tablet are usually temporary and subside with the completion of treatment. However, if these continue for a longer time, consult your doctor right away.
Furthermore, you should know that effect of Glyciphage SR 850 Tablet is Mild for pregnant women and Moderate for women who are breastfeeding. It is important to know if Glyciphage SR 850 Tablet has any effect on the kidney, liver and heart. Information on such adverse effects, if any, has been given in the Glyciphage SR 850 Tablet related warnings section.
Individuals suffering from medical conditions like Congestive Heart Failure (CHF), Anemia, Shock must refrain from the use of Glyciphage SR 850 Tablet since this can cause severe adverse effects. Other contraindications of Glyciphage SR 850 Tablet have been discussed in the sections ahead.
Drug reaction of Glyciphage SR 850 Tablet with other medicines has been reported. Refer to the list below for further details.
In addition to the above precautions for Glyciphage SR 850 Tablet, it is important to know that it is safe while driving, and is habit-forming.
Glyciphage SR 850 Tablet is used to treat the following -
Main Benefits
This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.
Find the right dosage based on disease and age
| Age Group | Dosage |
| Adult |
|
| Geriatric |
|
| 13 - 18 years (Adolescent) |
|
| 2 - 12 years (Child) |
|
Based on research, the following side effects have been observed when Glyciphage SR 850 Tablet is used -
Severe
Moderate
Mild
Common
Is the use of Glyciphage SR 850 Tablet safe for pregnant women?
Pregnant women may get mild side effects from Glyciphage.
Is the use of Glyciphage SR 850 Tablet safe during breastfeeding?
Breastfeeding women may feel side effects of Glyciphage. If you see any side effects, stop taking Glyciphage immediately and talk to your doctor. Take Glyciphage again, only after your doctor's advice.
What is the effect of Glyciphage SR 850 Tablet on the Kidneys?
Using Glyciphage does not have any harmful effects on kidneys.
What is the effect of Glyciphage SR 850 Tablet on the Liver?
There are no any side effects of Glyciphage on the liver.
What is the effect of Glyciphage SR 850 Tablet on the Heart?
There are no any side effects of Glyciphage for the heart.
Glyciphage SR 850 Tablet should not be taken with following medicines due to severe side effects it may cause to patients -
Severe
Moderate
If you are suffering from any of the following diseases, you should not take Glyciphage SR 850 Tablet unless your doctor advises you to do so -
Is this Glyciphage SR 850 Tablet habit forming or addictive?
Glyciphage SR 850 Tablet is not addictive in nature.
Is it safe to drive or operate heavy machinery when consuming?
Yes, you can comfortably use machinery or drive after taking Glyciphage SR 850 Tablet since it will not make you feel sleepy.
Is it safe?
Glyciphage SR 850 Tablet should be used only after doctor's advice.
Is it able to treat mental disorders?
No, Glyciphage SR 850 Tablet is not used to treat mental disorders.
Interaction between Food and Glyciphage SR 850 Tablet
Due to the absence of research, it is difficult to say how Glyciphage SR 850 Tablet and food will interact.
Interaction between Alcohol and Glyciphage SR 850 Tablet
Consult your doctor before consuming alcohol while taking Glyciphage SR 850 Tablet as it can have severe side effects.
Glyciphage can be taken forever, diabetes is a progressive disease it's possible that more medication and/or insulin may eventually need to be added to the regime.
Glyciphage works by decreasing the hepatic glucose production. It also works to lower blood sugar by increasing your sensitivity to insulin and decreasing the amount of glucose that is absorbed from the food you eat.
The long-term use can lead to the deficiency of Vitamin B12, which can further lead to megaloblastic anemia. Furthermore, Long-term Metformin use can also lead to kidney and liver problems.
Glyciphage should be taken with food to reduce stomach and bowel side effects, which may experience the first few weeks of treatment. Also, exercise regularly and test for sugar in your blood or urine as directed.
Lactic acidosis associated with Glyciphage treatment is a rare but fatal adverse effect. Lactic acidosis appears to result from biguanide interference causing an increase in production and decrease in clearance of lactate leading to higher cellular lactate levels. A decrease in pyruvate carboxylase activity, the rate-limiting enzyme in the formation of glucose from lactate, can also decrease hepatic metabolism of lactate. leading to increasing lactic acidosis. Signs and symptoms of Glyciphage induced lactic acidosis are nonspecific and include anorexia, nausea, vomiting, altered level of consciousness, hyperpnoea, abdominal pain, and thirst.
This medicine data has been created by -
B.Pharma, Pharmacy
5 Years of Experience
References
US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Glucophage® (metformin hydrochloride)
KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 275-276
April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 825-826
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