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  1. myUpchar
  2. Medicine
  3. Jakavi

Jakavi

  • Manufactured by: Novartis India Ltd
  • Contains / Salt: Ruxolitinib (20 mg)

Jakavi

Prescription Required

164 people have bought this recently


Select the variant of Jakavi

  • Jakavi 20 Tablet

  • Jakavi 15 Tablet

  • Jakavi 5 Tablet


  • In stock alternatives of Jakavi
    (based on Ruxolitinib (20 mg))
  • Jakavi 20 Tablet - ₹61367.0
  • Jakavi 15 Tablet - ₹56547.62
  • Jakavi 5 Tablet - ₹27600.0
  • Ruxolitinib Tablet - ₹30084.0
  • Manufactured by: Novartis India Ltd
  • Contains / Salt: Ruxolitinib (20 mg)

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  • In stock alternatives of Jakavi
    (based on Ruxolitinib (20 mg))
  • Jakavi 20 Tablet ₹61367.0
  • Jakavi 15 Tablet ₹56547.62
  • Jakavi 5 Tablet ₹27600.0
  • Ruxolitinib Tablet ₹30084.0
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  • Caluran CP Tablet ₹1046.55 ₹1090.16 4.0%
  • Letsure 5 Tablet ₹151.43 ₹212.0 28.57%

Jakavi Information

Jakavi is a commercial drug that is prescribed in the form of Tablet. It is primarily used for the treatment of Primary Myelofibrosis. Jakavi also has some secondary and off-label uses. These are listed below.

The correct dosage of Jakavi depends on the patient's age, gender, and medical history. Besides the medical condition it is advised for, the route of administration also plays an important role in determining the correct drug dosage. Detailed information has been provided in the dosage section.

Jakavi also has some side effects, the most common being Bruising or discoloration, Weight gain. Besides the aforementioned side effects, there are other adverse effects of Jakavi as well, which are listed below. Such side effects of Jakavi normally do not last long and go away once the treatment is completed. Please speak with your doctor if these side effects worsen or persist for a longer duration.

It is also important to note that Jakavi has a Unknown effect for pregnant women and Unknown effect on lactating mothers. It is important to know if Jakavi has any effect on the kidney, liver and heart. Information on such adverse effects, if any, has been given in the Jakavi related warnings section.

Jakavi can cause adverse effects in certain medical conditions. It is strongly recommended to avoid Jakavi in conditions like Drug Allergy, Anemia. Other contraindications of Jakavi have been discussed in the sections ahead.

Drug reaction of Jakavi with other medicines has been reported. Refer to the list below for further details.

You should also be aware that Jakavi is safe while driving, and is addiction.

  1. Jakavi Benefits & Uses
  2. Jakavi Dosage & How to Take
  3. Jakavi Side Effects
  4. Jakavi Related Warnings
  5. Severe Interaction of Jakavi with Other Drugs
  6. Jakavi Contraindications
  7. Frequently asked Questions about Jakavi
  8. Jakavi Interactions with Food and Alcohol

Jakavi Benefits & Uses

Jakavi is used to treat the following -

Main Benefits

  • Primary Myelofibrosis

Other Benefits

  • Polycythemia Vera

Jakavi Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult
  • Disease: Primary Myelofibrosis
  • Before or After Meal: Either
  • Single Maximum Dose: 20 mg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 2 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: Initial platelet count 100 to 200 x 10(9) cells/L can take 15 mg twice daily, 50 to 99 x 10(9) cells/L can take 5 mg twice daily
Geriatric
  • Disease: Primary Myelofibrosis
  • Before or After Meal: Either
  • Single Maximum Dose: 20 mg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 2 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: Initial platelet count 100 to 200 x 10(9) cells/L can take 15 mg twice daily, 50 to 99 x 10(9) cells/L can take 5 mg twice daily

Jakavi Side Effects

Based on research, the following side effects have been observed when Jakavi is used -

Severe

  • सिरदर्द
  • चक्कर आना (और पढ़ें - चक्कर आने पर करें ये घरेलू उपाय)
  • रक्त के प्लेटलेट में कमी
  • वर्टिगो

Moderate

  • एडिमा
  • उच्च रक्तचाप
  • कब्ज (और पढ़ें - कब्ज के घरेलू उपाय)

Mild

  • दस्त
  • थकान

Common

  • चोट या रंग बिगाड़ना
  • वजन बढ़ना

Jakavi Related Warnings

  • Is the use of Jakavi safe for pregnant women?


    The effects of Jakavi on pregnant women are unknown since no research has been done to ascertain it yet.

    Unknown
  • Is the use of Jakavi safe during breastfeeding?


    Information about safety of Jakavi for women who are breastfeeding is not available since scientific research on this is yet to be done.

    Unknown
  • What is the effect of Jakavi on the Kidneys?


    Kidney can be affected by Jakavi. If you experience any unwanted effects of this drug, stop taking it. You should take it again only after medical advice.

    Moderate
  • What is the effect of Jakavi on the Liver?


    Jakavi may cause harmful effects on liver. if you feel it's having any such effect, then stop taking this drug, and restart only on your doctor's advice.

    Moderate
  • What is the effect of Jakavi on the Heart?


    Jakavi may have mild side effects on the heart. Most people will never see any effect on the heart.

    Mild

Severe Interaction of Jakavi with Other Drugs

Jakavi should not be taken with following medicines due to severe side effects it may cause to patients -

Severe

Clarithromycin
  • Sompraz HP Combipack
  • Clariwin Dry Syrup
  • Pantop HP Kit
  • Acgel 1% Lotion
Indinavir
  • Indivan Capsule
  • Indivir Capsule
Itraconazole
  • Alcros 200 Capsule
  • Gitranox 200 Capsule
  • Itzhh 200 Capsule
  • Onitraz 100 Mg Capsule

Moderate

Carbamazepine
  • Mazetol SR 200 Tablet
  • Tegrital 200 Tablet
  • Tegrital 400 Tablet
  • Zeptol CR 300 Tablet

Jakavi Contraindications

If you are suffering from any of the following diseases, you should not take Jakavi unless your doctor advises you to do so -

  • Drug Allergy
  • Anemia
  • Fungal Infections
  • Liver Disease
  • Skin Cancer
  • Kidney Disease

Frequently asked Questions about Jakavi

  • Is this Jakavi habit forming or addictive?


    No, you will not get addicted to Jakavi.

    No
  • Is it safe to drive or operate heavy machinery when consuming?


    Yes, it is safe to do these activities or work after taking Jakavi as it does not make you drowsy.

    Safe
  • Is it safe?


    Jakavi is safe but it is important to consult a doctor before taking it.

    Safe, but take only on Doctor's advise
  • Is it able to treat mental disorders?


    Jakavi is unable to treat or cure mental disorders.

    No

Jakavi Interactions with Food and Alcohol

  • Interaction between Food and Jakavi


    Due to a lack of research, nothing can be said about the consequences of taking Jakavi together with food.

    Unknown
  • Interaction between Alcohol and Jakavi


    Due to lack of research, nothing can be said about side effects of consuming alcohol while taking Jakavi.

    Unknown

See all substitutes for Jakavi

  • Jakavi 20 Tablet - ₹61367.0
  • Jakavi 15 Tablet - ₹56547.62
  • Jakavi 5 Tablet - ₹27600.0
  • Ruxolitinib Tablet - ₹30084.0

This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
3 Years of Experience


References

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Jakafi™ (ruxolitinib)

  • 164 people have bought this recently
  • ₹61367.0
  • 14 Tablet in 1 Strip
  • Out of Stock
  • In stock alternatives of Jakavi
    (based on Ruxolitinib (20 mg))
  • Jakavi 20 Tablet ₹61367.0
  • Jakavi 15 Tablet ₹56547.62
  • Jakavi 5 Tablet ₹27600.0
  • Ruxolitinib Tablet ₹30084.0
  • You may also like
  • Armotraz Tablet ₹597.4 ₹628.89 5.01%
  • Caluran CP Tablet ₹1046.55 ₹1090.16 4.0%
  • Letsure 5 Tablet ₹151.43 ₹212.0 28.57%
₹61367.0
14 Tablet in 1 Strip

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Disclaimer: All information and articles available on this site are for educational purposes only. The information given here should not be used without any expert advice for the diagnosis or treatment of any health related problem or disease. Always seek the advice of a qualified doctor for medical examination and treatment.

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