Mercaptopurine



  • Manufactured by:
  • Contains / Salt: Mercaptopurine


Mercaptopurine Information



Mercaptopurine Benefits & Uses

Mercaptopurine is used to treat the following -

Main Benefits

  • B-Cell Acute Lymphoblastic Leukemia

Other Benefits

Mercaptopurine Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult
  • Disease: Ulcerative Colitis
  • Before or After Meal: Either
  • Single Maximum Dose: 1.5 mg/kg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 1 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor
Geriatric
  • Disease: Ulcerative Colitis
  • Before or After Meal: Either
  • Single Maximum Dose: 1.5 mg/kg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 1 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor
2 - 12 years (Child)
  • Disease: B-Cell Acute Lymphoblastic Leukemia
  • Before or After Meal: Either
  • Single Maximum Dose: 2.5 mg/kg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 1 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor
Infant (1 month to 2 years)
  • Disease: B-Cell Acute Lymphoblastic Leukemia
  • Before or After Meal: Either
  • Single Maximum Dose: 2.5 mg/kg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 1 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor


Mercaptopurine Side Effects

Based on research, the following side effects have been observed when Mercaptopurine is used -

Moderate

Mild

  • Diarrhoea
  • Loss of appetite
  • Infection
  • Rash
  • Nausea or vomiting
  • Urticaria

Mercaptopurine Related Warnings

  • Is the use of Mercaptopurine safe for pregnant women?


    Pregnant women may get severe side effects after taking Mercaptopurine. If you are pregnant, do not take Mercaptopurine without a doctor's advice.

    Severe
  • Is the use of Mercaptopurine safe during breastfeeding?


    Women who are breastfeeding, may experience serious side effects after taking Mercaptopurine. So it is adviced to consult the doctor before using it.

    Severe
  • What is the effect of Mercaptopurine on the Kidneys?


    Mercaptopurine can have moderate side effects on the kidney. If you notice any harmful effects, stop taking this drug right away. Consult your doctor before using this medicine again.

    Moderate
  • What is the effect of Mercaptopurine on the Liver?


    There may be an adverse effect on the liver after taking Mercaptopurine. If you observe any side effects on your body then stop taking this drug. Take this medicine again only if your doctor advises you to do so.

    Moderate
  • What is the effect of Mercaptopurine on the Heart?


    Mercaptopurine has very mild side effects on the heart.

    Mild


Severe Interaction of Mercaptopurine with Other Drugs

Mercaptopurine should not be taken with following medicines due to severe side effects it may cause to patients -

Severe



Mercaptopurine Contraindications

If you are suffering from any of the following diseases, you should not take Mercaptopurine unless your doctor advises you to do so -



Frequently asked Questions about Mercaptopurine

  • Is this Mercaptopurine habit forming or addictive?


    No, there is no any evidence that Mercaptopurine is addictive.

    No
  • Is it safe to drive or operate heavy machinery when consuming?


    After taking Mercaptopurine you may feel sleepy. So it is not advised to perform these activities.

    Dangerous
  • Is it safe?


    Yes, Mercaptopurine is safe but you must consult your doctor before taking it.

    Safe, but take only on Doctor's advise
  • Is it able to treat mental disorders?


    There is no benefit of taking Mercaptopurine for mental disorders.

    No

Mercaptopurine Interactions with Food and Alcohol

  • Interaction between Food and Mercaptopurine


    It is safe to take Mercaptopurine with food.

    Safe
  • Interaction between Alcohol and Mercaptopurine


    It is difficult to say anything about the effect of Mercaptopurine and alcohol. No research has been done on this yet.

    Unknown


See all substitutes for Mercaptopurine


This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience


References

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Purixan (mercaptopurine)

KD Tripathi. Essentials of Medical Pharmacology. Eighth Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2019



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