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Methadone Information

Methadone Benefits & Uses

Methadone is used to treat the following -

Methadone Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

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Ingredients of Methadone


Methadone Side Effects

Based on research, the following side effects have been observed when Methadone is used -

  1. Dizziness Mild
  2. Dry Mouth Mild
  3. Palpitations (fluttering in chest)
  4. Urine Retention
  5. Nausea or vomiting
  6. Constipation Moderate
  7. Headache Mild
  8. Urticaria
  9. Agitation
  10. Edema Moderate

Methadone Related Warnings

Is the use of Methadone safe for pregnant women?

Methadone can cause unwanted side effects in pregnant women. If you experience any side effects, stop taking Methadone right away. Take your doctor's advice before taking it again.


Is the use of Methadone safe during breastfeeding?

Methadone may have very limited harmful effects for breastfeeding women.


What is the effect of Methadone on the Kidneys?

Methadone rarely affects the kidneys.


What is the effect of Methadone on the Liver?

Very few cases of side effects of Methadone on the liver have been reported.


What is the effect of Methadone on the Heart?

Methadone has very mild side effects on the heart.


Severe Interaction of Methadone with Other Drugs

Methadone should not be taken with following medicines due to severe side effects it may cause to patients -

Methadone Contraindications

If you are suffering from any of the following diseases, you should not take Methadone unless your doctor advises you to do so -

  1. Heart Disease
  2. Coronary Artery Disease (CAD)
  3. Diabetes
  4. Depression
  5. Pancreatitis
  6. Ulcerative Colitis
  7. Asthma
  8. COPD (Chronic Obstructive Pulmonary Disease)
  9. Liver Disease
  10. Kidney Disease

Frequently asked Questions about Methadone

Is this Methadone habit forming or addictive?

Methadone is not addictive in nature.


Is it safe to drive or operate heavy machinery when consuming?

After taking Methadone you may feel sleepy. So it is not advised to perform these activities.


Is it safe?

Methadone is safe but it is important to consult a doctor before taking it.

Safe, but take only on Doctor's advise

Is it able to treat mental disorders?

Yes, taking Methadone can treat mental disorders.


Methadone Interactions with Food and Alcohol

Interaction between Food and Methadone

Taking Methadone with food does not cause any problems.


Interaction between Alcohol and Methadone

Taking Methadone with alcohol can have severely harmful effects on your health.

This medicine data has been created by -
Dr. Md Saadullah
M.Pharma, Pharmacy
3 Years of Experience
View Doctor Profile
Dr. Vikas Chauhan
B.Pharma, Pharmacy
2 Years of Experience
View Doctor Profile

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  1. April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 827-828
  2. KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 476
  3. US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Dolophine® Hydrochloride (methadone hydrochloride)
  4. US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Methadose™ Oral Concentrate (methadone hydrochloride oral concentrate)