Mistol

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Mistol Information

Mistol, a prescription drug, is manufactured in various forms such as Tablet. It is primarily used for the treatment of Abortion. The alternative uses of Mistol have also been explained below.

The right dosage of Mistol depends on the age, gender, and medical history of the patient. Dosage also depends on the route of administration and your chief complaint for which the drug is prescribed. Refer to the dosage section for a detailed discussion.

Apart from the aforementioned side effects, Mistol can also lead to other problems, which have been listed below. These side effects of Mistol are usually temporary and subside with the completion of treatment. Consult your doctor if these side effects become worse or stay for a longer duration.

Furthermore, you should know that effect of Mistol is Severe for pregnant women and Moderate for women who are breastfeeding. It is important to know if Mistol has any effect on the kidney, liver and heart. Information on such adverse effects, if any, has been given in the Mistol related warnings section.

Other conditions have been mentioned below in the Mistol contraindications section.

Drug reaction of Mistol with other medicines has been reported. See below for a complete list.

Along with the above-mentioned precautions, remember that taking Mistol is considered safe while driving, and is addictive.



Mistol Benefits & Uses

Mistol is used to treat the following -

Other Benefits

Mistol Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult
  • Disease: Peptic Ulcer
  • Before or After Meal: With meal
  • Single Maximum Dose: 200 mcg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 4 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor
Geriatric
  • Disease: Peptic Ulcer
  • Before or After Meal: With meal
  • Single Maximum Dose: 200 mcg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 4 hourly
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor
Adult(Female)
  • Disease: Post Delivery Bleeding
  • Before or After Meal: Either
  • Single Maximum Dose: 600 mcg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: once only
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor

Mistol Related Warnings

  • Is the use of Mistol safe for pregnant women?


    Pregnant women may get severe side effects after taking Mistol. If you are pregnant, do not take Mistol without a doctor's advice.

    Severe
  • Is the use of Mistol safe during breastfeeding?


    Women who are breastfeeding can experience some moderate side effects of Mistol. Immediately discontinue Mistol if you observe any side effects. Contact your doctor, and restart using it only if your doctor considers it safe for you.

    Moderate
  • What is the effect of Mistol on the Kidneys?


    Mistol rarely harms the kidneys.

    Mild
  • What is the effect of Mistol on the Liver?


    The liver can be affected by Mistol. If you experience any unwanted effects of this drug, stop taking it and consult your doctor. You should restart Mistol only after medical advice.

    Moderate
  • What is the effect of Mistol on the Heart?


    The heart can be affected by Mistol. If you experience any unwanted effects of this drug, stop taking it and consult your doctor. You should restart the medicine only after medical advice.

    Moderate


Severe Interaction of Mistol with Other Drugs

Mistol should not be taken with following medicines due to severe side effects it may cause to patients -

Severe

Moderate

Mild



Mistol Contraindications

If you are suffering from any of the following diseases, you should not take Mistol unless your doctor advises you to do so -



Frequently asked Questions about Mistol

  • Is this Mistol habit forming or addictive?


    Mistol is not addictive in nature.

    No
  • Is it safe to drive or operate heavy machinery when consuming?


    Yes, you can operate a vehicle or heavy machinery after taking Mistol since it does not cause drowsiness.

    Safe
  • Is it safe?


    Yes, but consume Mistol only on doctor's advice.

    Safe, but take only on Doctor's advise
  • Is it able to treat mental disorders?


    There is no benefit of taking Mistol for mental disorders.

    No

Mistol Interactions with Food and Alcohol

  • Interaction between Food and Mistol


    Information is not available on the interaction of any foods with Mistol, due to a lack of research on this.

    Unknown
  • Interaction between Alcohol and Mistol


    Due to lack of research, there is no information about the side effects of taking Mistol with alcohol.

    Unknown


Frequently asked Questions about Mistol

Question about 4 years ago

Is Mistol used for ulcer?

Dr. Chinmaya Bal MBBS , General Physician

Yes, Mistol is used to prevent and treat NSAIDs (nonsteroidal anti-inflammatory drugs) induced stomach ulcers. It works by inhibiting gastric acid secretion. NSAIDs (nonsteroidal anti-inflammatory drugs) inhibits the synthesis of prostaglandins which leads to diminishing bicarbonate and mucus (phlegm) secretion which contributes to ulceration. Mistol has mucosal protective properties that protect the stomach tissues from the damage caused by the stomach acid through decreased acid secretion and mucosal protective action.

Question over 5 years ago

How does Mistol work?

Dr. Suhas Bhargav MBBS , General Physician

Mistol contains misoprostol which is a prostaglandin E1 (PGE1) analogue that possesses antisecretory property that inhibits gastric acid secretion. NSAIDs (nonsteroidal anti-inflammatory drugs) inhibits the synthesis of prostaglandins which leads to diminishing bicarbonate and mucus secretion which contributes to ulceration. Mistol has mucosal protective properties that protect the stomach tissues from the damage caused by the stomach acid through decreased acid secretion and mucosal protective action. It induces labour by causing relaxation of cervix uteri (which is the lower part of the uterus). In the treatment of postpartum hemorrhage Mistol works by causing contractions of smooth muscle fibres of the myometrium (middle layer of the uterine wall).

Question about 5 years ago

How to take Mistol?

Dr. Kuldeep Meena MBBS, MD , Cardiology, Neurology, Pediatrics, Dermatology, Pulmonology, Nephrology, General Physician, Other, Infectious Disease, Emergency Medicine, Allergy and Immunology, Internal Medicine, Multispeciality

The dosage of Mistol may vary from case to case and type of condition in which the drug is being given. You are advised to take Mistol as prescribed by your doctor. Ideally, it should be taken with the food to minimize the possibility of stomach irritation that can result in diarrhoea. Precautions must be taken in patients with known inflammatory bowel disease, improper kidney function, coronary artery disease, and hypertension.

Question over 4 years ago

How much time Mistol takes to work for abortion?

If Mistol is taken alone without mifepristone then it takes around 10–15 hours interval for abortion but in most of the women upto 80%–90% will abort within 24 hours interval.

Question over 4 years ago

What to do if Mistol doesn't work?

Dr. Vedprakash Verma MBBS, MD , Cardiology

The chances of Mistol to not work are very slim, however if the woman fails to abort within 24 hours after taking the first dose of Mistol and if no significant side effects were observed when a second course of Mistol can be given after 12 hours of the last dose of Mistol.



See all substitutes for Mistol


This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience


References

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 867

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 654

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Cytotec® (misoprostol)



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