Onconase Information

Onconase is a commercial drug that is prescribed in the form of Injection. It is primarily used for the treatment of Blood Cancer.

The optimal dosage of Onconase is largely dependent on the individual's body weight, medical history, gender and age. Dosage also depends on the route of administration and your chief complaint for which the drug is prescribed. For detailed information on this, read through the dosage section.

Common side effects of Onconase include Rash, Nausea or vomiting, Increased Liver Enzymes. Such side effects of Onconase normally do not last long and go away once the treatment is completed. If, however, they worsen or do not go away, please speak with your physician.

Onconase's effect during pregnancy is Moderate and Severe while nursing. In addition, Onconase's effects on the liver, heart and kidney are discussed below in the Onconase related warnings section.

Individuals suffering from medical conditions like Bleeding, Pancreatitis must refrain from the use of Onconase since this can cause severe adverse effects. Other conditions have been mentioned below in the Onconase contraindications section.

Drug reaction of Onconase with other medicines has been reported. See below for a complete list.

In addition to these precautions, you may also note that Onconase is not safe while driving, and is is not addictive in nature.

Onconase Benefits & Uses
Onconase Dosage & How to Take
Onconase Side Effects
Onconase Related Warnings
Severe Interaction of Onconase with Other Drugs
Onconase Contraindications
Frequently asked Questions about Onconase
Onconase Interactions with Food and Alcohol

Onconase Benefits & Uses

Onconase is used to treat the following -

Other Benefits

Chronic Myelogenous Leukemia

Onconase Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group	Dosage
13 - 18 years (Adolescent)	Disease: Blood Cancer Before or After Meal: As advised by a physician Single Maximum Dose: 200 units/kg Dosage Route: Parenteral Frequency: 1 daily Course Duration: 4 weeks Special Instructions: As prescribed by the doctor
2 - 12 years (Child)	Disease: Blood Cancer Before or After Meal: As advised by a physician Single Maximum Dose: 200 units/kg Dosage Route: Parenteral Frequency: 1 daily Course Duration: 4 weeks Special Instructions: As prescribed by the doctor

Onconase Related Warnings

Is the use of Onconase safe for pregnant women?

Onconase may cause moderate side effects during pregnancy. If you feel its harmful effects, then stop taking this drug immediately, and do not take Onconase again without your doctor's advice.

Moderate
Is the use of Onconase safe during breastfeeding?

Onconase may cause serious side effects in breastfeeding women, so do not take this drug without doctor's advice.

Severe
What is the effect of Onconase on the Kidneys?

Onconase rarely affects the kidneys.

Mild
What is the effect of Onconase on the Liver?

The liver can be affected by Onconase. If you experience any unwanted effects of this drug, stop taking it and consult your doctor. You should restart Onconase only after medical advice.

Moderate
What is the effect of Onconase on the Heart?

Onconase is not harmful for the heart.

Safe

Severe Interaction of Onconase with Other Drugs

Onconase should not be taken with following medicines due to severe side effects it may cause to patients -

Severe

Thalidomide

Moderate

Acarbose

Alogliptin

Alogliptin Tablet

Metformin

Methotrexate

Carbamazepine

Onconase Contraindications

If you are suffering from any of the following diseases, you should not take Onconase unless your doctor advises you to do so -

Liver Disease
Bleeding
Pancreatitis
Diabetes

Frequently asked Questions about Onconase

Is this Onconase habit forming or addictive?

Onconase is not addictive in nature.

No
Is it safe to drive or operate heavy machinery when consuming?

After taking Onconase, you should not drive or work on any heavy machine, as Onconase can make you drowsy.

Dangerous
Is it safe?

Yes, but consume Onconase only on doctor's advice.

Safe, but take only on Doctor's advise
Is it able to treat mental disorders?

There is no benefit of taking Onconase for mental disorders.

No

Onconase Interactions with Food and Alcohol

Interaction between Food and Onconase

Taking Onconase with food is safe.

Safe
Interaction between Alcohol and Onconase

Due to lack of research, nothing can be said about side effects of consuming alcohol while taking Onconase.

Unknown

See all substitutes for Onconase

This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience

References

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Elspar® (Asparaginase)

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 868-869

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 190-191

Onconase