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What is chronic myelogenous leukaemia?

Chronic myelogenous leukaemia (CML), otherwise called chronic myeloid leukaemia, is a cancer of the blood cells and bone marrow. The bone marrow is the soft part of the bone where blood cells are produced. CML is a form of leukaemia in which there is uncontrolled growth of white blood cells.

What are its main signs and symptoms?

  • Patients with CML may show no symptoms when they are in the chronic phase of the disease.
  • In the next phase called the accelerated phase, night sweats, fatigue, weight loss and persistent fever are common symptoms.
  • The patient has severe symptoms in a phase called the blastic phase, which includes pain, infections and spontaneous bleeding.
  • Due to the abnormality in the white blood cell number and structure, the spleen is also affected. A person may complain of pain in the upper abdomen due to enlargement of the spleen.

What are its main causes?

  • Unfortunately, the exact cause of CML has not yet been identified.
  • A prevalent risk factor is an exposure to high amounts of radiation.
  • The cancer is associated with a defect in chromosome 22 of humans, which is a common finding in a majority of the people suffering from CML. This chromosome is termed the Philadelphia chromosome.
  • The condition is more common in middle-aged individuals, and men are affected more than women.

How is it diagnosed and treated?

  • A basic physical exam will give your doctor an idea of vital parameters like blood pressure, heart rate and pulse. Any swelling in the lymph nodes or spleen is also checked for.
  • Blood examination reveals the abnormality in the number and form of the blood cells.
  • Special tests are conducted to check for the Philadelphia chromosome, like the polymerase chain reaction test.
  • A biopsy of the bone marrow is also diagnostic for malignancy.
  • It is difficult to eliminate all the cells containing the defective gene, but the treatment aims at destroying these cells.
  • Apart from chemotherapy, there are specific drugs called targeted drugs for CML patients. If a person develops resistance to one targeted drug, another drug is prescribed.
  • A bone marrow transplant is the closest chance that a patient has for a complete cure. The donor cells stimulate the formation of new healthy cells in the bone marrow.
  • Despite ongoing research for better treatment options, especially for the treatment of resistant CML, the condition continues to have a poor prognosis.
  1. Medicines for Chronic Myelogenous Leukemia (CML)

Medicines for Chronic Myelogenous Leukemia (CML)

Medicines listed below are available for Chronic Myelogenous Leukemia (CML). Please note that you should not take any medicines without doctor consultation. Taking any medicine without doctor's consultation can cause serious problems.

Medicine NamePack SizePrice (Rs.)
CelonibCelonib 100 Mg Capsule900.0
ChemotinibChemotinib 100 Mg Capsule279.0
IbatkinIbatkin 100 Mg Capsule904.76
ImatImat 100 Mg Tablet455.65
LeukanibLeukanib 100 Mg Tablet1100.0
VeenatVeenat 100 Mg Capsule855.0
AltanibAltanib 400 Mg Tablet3110.84
CadinibCadinib 400 Mg Tablet3675.15
GlivecGlivec 400 Mg Tablet3110.0
ImalekImalek 100 Mg Tablet875.9
ImanibImanib 100 Mg Capsule670.46
Imatib AImatib A 100 Mg Capsule575.0
ImatibImatib 100 Mg Capsule937.81
ImatinibImatinib 100 Mg Tablet915.38
LevinLevin 250 Mg Tablet42.86
Levin(Drl)Levin 100 Mg Tablet943.86
LupinibLupinib 100 Mg Tablet470.0
MitinabMitinab 100 Mg Tablet900.0
ShantinibShantinib 100 Mg Capsule875.0
TiminibTiminib 400 Mg Capsule3500.0
UnitinibUnitinib 400 Mg Capsule3339.0
ZealataZealata 400 Mg Tablet3454.5
CytodroxCytodrox 500 Mg Capsule135.0
DureaDurea 500 Mg Capsule147.62
HondreaHondrea 500 Mg Capsule122.44
HydabHydab 500 Mg Capsule152.0
Hydrox LHydrox L 500 Mg Capsule72.86
MyelostatMyelostat 500 Mg Capsule103.7
MylostatMylostat 500 Mg Capsule94.64
OndreaOndrea 500 Mg Capsule55.58
RiboreaRiborea 500 Mg Capsule120.0
UnidreaUnidrea 500 Mg Capsule124.0
HydranHydran 500 Mg Capsule100.0
HydreaHydrea 100 Mg Capsule138.47
HydrogemHydrogem 500 Mg Capsule50.0
HydroxHydrox 500 Mg Capsule73.25
LeukocelLeukocel 500 Mg Tablet140.0
NeodreaNeodrea 500 Mg Capsule82.8
HytasHytas 1000 Mg Capsule46.18
SprycelSprycel 50 Mg Tablet208283.0

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