Diphenhydramine

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Diphenhydramine Information

Diphenhydramine is a prescription medicine. Primarily, it is used for the treatment of Allergy, Motion Sickness, Allergic Rhinitis. Other than this, Diphenhydramine has some other therapeutic uses, which have been discussed ahead.

The optimal dosage of Diphenhydramine is largely dependent on the individual's body weight, medical history, gender and age. Dosage also depends on the route of administration and your chief complaint for which the drug is prescribed. Detailed information has been provided in the dosage section.

Diphenhydramine also has some side effects, the most common being Unsteadiness. Some other side effects of Diphenhydramine have been listed ahead. Normally, these side effects of Diphenhydramine are not long lasting and go away when the treatment is finished. Consult your doctor if these side effects become worse or stay for a longer duration.

In addition, Diphenhydramine's effect is Moderate during pregnancy and Severe for lactating mothers. It is important to know if Diphenhydramine has any effect on the kidney, liver and heart. Information on such adverse effects, if any, has been given in the Diphenhydramine related warnings section.

Diphenhydramine is contraindicated in people with pre-existing medical conditions like Peptic Ulcer, Depression as it can result in adverse effects. The section on Diphenhydramine contraindications lists all such conditions.

Additionally, Diphenhydramine may also adversely react with other medicines. A complete list of these interactions is given below.

In addition to the above precautions for Diphenhydramine, it is important to know that it is not safe while driving, and is not habit-forming.



Diphenhydramine Benefits & Uses

Diphenhydramine is used to treat the following -

Other Benefits

Diphenhydramine Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage

Diphenhydramine Related Warnings

  • Is the use of Diphenhydramine safe for pregnant women?


    Diphenhydramine can cause unwanted side effects in pregnant women. If you experience any side effects, stop taking Diphenhydramine right away. Take your doctor's advice before taking it again.

    Moderate
  • Is the use of Diphenhydramine safe during breastfeeding?


    Diphenhydramine may cause serious side effects in breastfeeding women, so do not take this drug without doctor's advice.

    Severe
  • What is the effect of Diphenhydramine on the Kidneys?


    Diphenhydramine has very mild side effects on the kidneys.

    Mild
  • What is the effect of Diphenhydramine on the Liver?


    Diphenhydramine can have moderate side effects on the liver. If you notice any harmful effects then stop taking this drug right away. Consult your doctor before using this medicine again.

    Moderate
  • What is the effect of Diphenhydramine on the Heart?


    Diphenhydramine has very mild side effects on the heart.

    Mild


Severe Interaction of Diphenhydramine with Other Drugs

Diphenhydramine should not be taken with following medicines due to severe side effects it may cause to patients -

Severe

Moderate



Diphenhydramine Contraindications

If you are suffering from any of the following diseases, you should not take Diphenhydramine unless your doctor advises you to do so -



Frequently asked Questions about Diphenhydramine

  • Is this Diphenhydramine habit forming or addictive?


    Diphenhydramine does not cause addiction.

    No
  • Is it safe to drive or operate heavy machinery when consuming?


    After taking Diphenhydramine you may feel sleepy. So it is not advised to perform these activities.

    Dangerous
  • Is it safe?


    Diphenhydramine is safe but it is important to consult a doctor before taking it.

    Safe, but take only on Doctor's advise
  • Is it able to treat mental disorders?


    There is no benefit of taking Diphenhydramine for mental disorders.

    No

Diphenhydramine Interactions with Food and Alcohol

  • Interaction between Food and Diphenhydramine


    Due to the absence of research, it is difficult to say how Diphenhydramine and food will interact.

    Unknown
  • Interaction between Alcohol and Diphenhydramine


    Taking alcohol with Diphenhydramine can be dangerous.

    Severe


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This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience


References

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 441-443

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 663

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Diphenhydramine (diphenhydramine hydrochloride)

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