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Glyrep 500 Tablet is a commercial drug that is prescribed in the form of Tablet. Primarily, it is used for the treatment of Diabetes.
The optimal dosage of Glyrep 500 Tablet is largely dependent on the individual's body weight, medical history, gender and age. Besides the medical condition it is advised for, the route of administration also plays an important role in determining the correct drug dosage. Detailed information has been provided in the dosage section.
Common side effects of Glyrep 500 Tablet include Stomach Upset, Difficulty urinating. Apart from the aforementioned side effects, Glyrep 500 Tablet can also lead to other problems, which have been listed below. Such side effects of Glyrep 500 Tablet normally do not last long and go away once the treatment is completed. However, if these continue for a longer time, consult your doctor right away.
It is also important to note that Glyrep 500 Tablet has a Mild effect for pregnant women and Moderate effect on lactating mothers. In addition, Glyrep 500 Tablet's effects on the liver, heart and kidney are discussed below in the Glyrep 500 Tablet related warnings section.
Individuals suffering from medical conditions like Congestive Heart Failure (CHF), Anemia, Shock must refrain from the use of Glyrep 500 Tablet since this can cause severe adverse effects. Some other conditions that can be affected by Glyrep 500 Tablet are listed in the contraindications section below.
Drug interactions for Glyrep 500 Tablet have been reported in the medical literature. Refer to the list below for further details.
In addition to these precautions, you may also note that Glyrep 500 Tablet is safe while driving, and is is addictive in nature.
Glyrep 500 Tablet is used to treat the following -
Main Benefits
This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.
Find the right dosage based on disease and age
Age Group | Dosage |
Adult |
|
Geriatric |
|
13 - 18 years (Adolescent) |
|
2 - 12 years (Child) |
|
Is the use of Glyrep 500 Tablet safe for pregnant women?
Pregnant women may get mild side effects from Glyrep.
Is the use of Glyrep 500 Tablet safe during breastfeeding?
Breastfeeding women may feel side effects of Glyrep. If you see any side effects, stop taking Glyrep immediately and talk to your doctor. Take Glyrep again, only after your doctor's advice.
What is the effect of Glyrep 500 Tablet on the Kidneys?
Glyrep does not damage the kidneys.
What is the effect of Glyrep 500 Tablet on the Liver?
Glyrep is completely safe for the liver.
What is the effect of Glyrep 500 Tablet on the Heart?
Glyrep is completely safe for the heart.
If you are suffering from any of the following diseases, you should not take Glyrep 500 Tablet unless your doctor advises you to do so -
Is this Glyrep 500 Tablet habit forming or addictive?
No, there is no any evidence that Glyrep 500 Tablet is addictive.
Is it safe to drive or operate heavy machinery when consuming?
Yes, you can comfortably use machinery or drive after taking Glyrep 500 Tablet since it will not make you feel sleepy.
Is it safe?
Glyrep 500 Tablet should be used only after doctor's advice.
Is it able to treat mental disorders?
No, the use of Glyrep 500 Tablet in mental disorders is not effective.
Interaction between Food and Glyrep 500 Tablet
Due to a lack of research, nothing can be said about the consequences of taking Glyrep 500 Tablet together with food.
Interaction between Alcohol and Glyrep 500 Tablet
Taking alcohol with Glyrep 500 Tablet can be dangerous.
Yes, Glyrep can cause low blood sugar (hypoglycemia). However, this can also occur if you delay or miss a meal, drink alcohol, exercise more than usual, can't eat due to stomach upset, and taking other antidiabetic medicine with metformin. So, regular monitoring of blood glucose level is needed and be cautious of symptoms of hypoglycemia, always keep glucose-rich food with you.
Yes, Glyrep can cause some sleep problems, especially insomnia. On the other hand, Glyrep has proven to be useful for preventing sleep apnea. The exact relationship between Glyrep and sleep problems is still not clear, and further studies are needed for a clearer understanding.
Glyrep increases the sensitivity of insulin, young women with PCOS often have elevated insulin levels and are more likely to develop diabetes. It is often prescribed for women with PCOS to help prevent diabetes. A lifestyle that includes healthy nutrition and daily exercise is the most important part of a PCOS treatment plan.
Yes, Glyrep can be taken with the statin. There is no serious or harmful interaction have been observed between them. Some studies say that it's possible your blood sugar (blood glucose) level may increase when you take a statin, which may lead to developing type 2 diabetes. The risk is small but important enough that the Food and Drug Administration (FDA) has issued a warning on statin labels regarding blood glucose levels and diabetes.
Lactic acidosis associated with Glyrep treatment is a rare but fatal adverse effect. Lactic acidosis appears to result from biguanide interference causing an increase in production and decrease in clearance of lactate leading to higher cellular lactate levels. A decrease in pyruvate carboxylase activity, the rate-limiting enzyme in the formation of glucose from lactate, can also decrease hepatic metabolism of lactate. leading to increasing lactic acidosis. Signs and symptoms of Glyrep induced lactic acidosis are nonspecific and include anorexia, nausea, vomiting, altered level of consciousness, hyperpnoea, abdominal pain, and thirst.
This medicine data has been created by -
B.Pharma, Pharmacy
5 Years of Experience
References
US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Glucophage® (metformin hydrochloride)
KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 275-276
April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 825-826