Esperal

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Esperal Information

Esperal is a prescription drug, available for use as Tablet. It is typically used for the treatment of Alcoholism.

Medical history of the patient along with age and gender determines the dosage of Esperal. Individual symptoms and route of administration also determines the right dosage. Detailed information has been provided in the dosage section.

Besides the aforementioned side effects, there are other adverse effects of Esperal as well, which are listed below. Usually, these side effects of Esperal go away soon, and do not persist beyond the duration of the treatment. If, however, they worsen or do not go away, please speak with your physician.

In addition, Esperal's effect is Moderate during pregnancy and Severe for lactating mothers. Further, the section on Esperal related warnings talks about Esperal's effects on the liver, heart and kidney.

Esperal is contraindicated in people with pre-existing medical conditions like Heart Disease, Psychosis as it can result in adverse effects. Some other conditions that can be affected by Esperal are listed in the contraindications section below.

Drug interactions for Esperal have been reported in the medical literature. See below for a complete list.

In addition to the above precautions for Esperal, it is important to know that it is not safe while driving, and is not habit-forming.



Esperal Benefits & Uses

Esperal is used to treat the following -

Main Benefits

Esperal Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult
  • Disease: Alcoholism
  • Before or After Meal: After Meal
  • Single Maximum Dose: 500 mg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 1 daily
  • Course Duration: 2 weeks
  • Special Instructions: Later decrease dose up to 250 mg once daily, dosage regime: from months to years
Geriatric
  • Disease: Alcoholism
  • Before or After Meal: After Meal
  • Single Maximum Dose: 500 mg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 1 daily
  • Course Duration: 2 weeks
  • Special Instructions: Later decrease dose up to 250 mg once daily, dosage regime: from months to years

Esperal Related Warnings

  • Is the use of Esperal safe for pregnant women?


    Esperal can cause unwanted side effects in pregnant women. If you experience any side effects, stop taking Esperal right away. Take your doctor's advice before taking it again.

    Moderate
  • Is the use of Esperal safe during breastfeeding?


    Women who are breastfeeding may experience severe harmful effects after taking Esperal. It should only be taken after medical advice.

    Severe
  • What is the effect of Esperal on the Kidneys?


    Esperal may have mild side effects on the kidneys.

    Mild
  • What is the effect of Esperal on the Liver?


    Esperal is rarely harmful for the liver.

    Mild
  • What is the effect of Esperal on the Heart?


    Esperal has very mild side effects on the heart.

    Mild


Severe Interaction of Esperal with Other Drugs

Esperal should not be taken with following medicines due to severe side effects it may cause to patients -

Severe

Moderate

Mild



Esperal Contraindications

If you are suffering from any of the following diseases, you should not take Esperal unless your doctor advises you to do so -



Frequently asked Questions about Esperal

  • Is this Esperal habit forming or addictive?


    Forming a habit of Esperal has not been reported.

    No
  • Is it safe to drive or operate heavy machinery when consuming?


    No, you should do not do anything that requires concentration and attention as the Esperal can make you feel drowsy.

    Dangerous
  • Is it safe?


    Yes, but take Esperal only as per medical advice.

    Safe, but take only on Doctor's advise
  • Is it able to treat mental disorders?


    There is no benefit of taking Esperal for mental disorders.

    No

Esperal Interactions with Food and Alcohol

  • Interaction between Food and Esperal


    You can take Esperal with food.

    Safe
  • Interaction between Alcohol and Esperal


    Consumption of alcohol and Esperal together may have severe effects on your health.

    Severe


Frequently asked Questions about Esperal

Question over 5 years ago

How does Esperal work?

Dr. Saurabh Shakya MBBS , General Physician

Esperal works by causing unpleasant effects when even small amounts of alcohol are consumed, which reduces the desire to drink. These effects include flushing of the face, headache, nausea, vomiting, choking, and anxiety. These effects begin about 10 minutes after alcohol enters the body and lasts for 1 hour or more. This drug is used as a part of a recovery program that includes medical supervision and counseling.

Question almost 5 years ago

Does Esperal induce sleepiness?

Dr. Gaurav MBBS , General Physician

Yes Esperal causes drowsiness, dizziness or sedation. It is one of the most common side effects of this medicine. Do not drive any vehicle or operate machinery after taking this medicine as it causes drowsiness.

Question almost 5 years ago

Does Esperal cause constipation?

Dr. MBBS , General Physician, Other, Obstetrics & Gynaecology

No, Esperal does not cause constipation in patients who are taking it. However, if you are experiencing constipation after taking this drug then inform your doctor and take precautionary methods such as eating fibrous foods to avoid constipation.

Question almost 5 years ago

Does Esperal stop cravings?

Dr. Kishan Barnwal MBBS , General Physician

Yes, Esperal does helps in reducing alcohol cravings. It has facilitated clinical benefits in reducing alcohol craving by providing additional psychological support.

Question over 5 years ago

What is Esperal?

Dr. Surender Kumar MBBS , General Physician

Esperal is a brand name of disulfiram. It is a prescription drug that belongs to the class of drugs known as alcohol deterrents (detoxifying agents). It is used for the treatment and management of chronic alcoholism.



See all substitutes for Esperal


This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience


References

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 394

Therapeutic Goods Administration (TGA): Department of Health [Internet]. Governmet of Australia; Package leaflet information for the user; Antabuse® (disulfiram)



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