Holoxan 500 Injection Information

Holoxan 500 Injection is a prescription drug, available for use as Injection. It is typically used for the treatment of Testicular Cancer, Cervical Cancer. Holoxan 500 Injection also has some secondary and off-label uses. These are listed below.

The right dosage of Holoxan 500 Injection depends on the age, gender, and medical history of the patient. Besides the medical condition it is advised for, the route of administration also plays an important role in determining the correct drug dosage. For detailed information on this, read through the dosage section.

Apart from the aforementioned side effects, Holoxan 500 Injection can also lead to other problems, which have been listed below. Usually, these side effects of Holoxan 500 Injection go away soon, and do not persist beyond the duration of the treatment. If, however, they worsen or do not go away, please speak with your physician.

Furthermore, you should know that effect of Holoxan 500 Injection is Severe for pregnant women and Severe for women who are breastfeeding. Warnings related to Holoxan 500 Injection's effects on the liver, heart and kidney, if any, have been listed below.

Individuals suffering from medical conditions like Herpes, Infections must refrain from the use of Holoxan 500 Injection since this can cause severe adverse effects. The section on Holoxan 500 Injection contraindications lists all such conditions.

Drug reaction of Holoxan 500 Injection with other medicines has been reported. Refer to the list below for further details.

In addition to these precautions, you may also note that Holoxan 500 Injection is not safe while driving, and is is not addictive in nature.

Holoxan Benefits & Uses
Holoxan Dosage & How to Take
Holoxan Side Effects
Holoxan Related Warnings
Severe Interaction of Holoxan with Other Drugs
Holoxan Contraindications
Frequently asked Questions about Holoxan
Holoxan Interactions with Food and Alcohol

Holoxan 500 Injection Benefits & Uses

Holoxan 500 Injection is used to treat the following -

Other Benefits

Cancer: causes, symptoms, treatment, medicines, prevention and medicines

Holoxan 500 Injection Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group	Dosage
Adult(Male)	Disease: Before or After Meal: As advised by a physician Single Maximum Dose: 2000 mg Dosage Route: Parenteral Frequency: 1 daily Course Duration: 5 days Special Instructions: As prescribed by the doctor
Geriatric	Disease: Before or After Meal: As advised by a physician Single Maximum Dose: 2000 mg Dosage Route: Parenteral Frequency: 1 daily Course Duration: 5 days Special Instructions: As prescribed by the doctor
Adult(Female)	Disease: Before or After Meal: As advised by a physician Single Maximum Dose: 3000 mg Dosage Route: Parenteral Frequency: 1 daily Course Duration: 3 days Special Instructions: In combination with other chemotherapeutic agents as a part of the BIC regimen

Holoxan 500 Injection Side Effects

Based on research, the following side effects have been observed when Holoxan 500 Injection is used -

Severe

Seizures (uncontrollable jerking of limbs)
Coma

Moderate

Anemia (Read More - Home Remedies for Anaemia)
Decreased white blood cell count (neutrophils)
Jaundice (Read More - Home Remedies for Jaundice)
Stomatitis (Inflammation of the mouth)

Mild

Nausea or vomiting
Hair Loss
Infection
Tremor
Dizziness (Read More - Home Remedies for Dizziness: Quick Tips for Instant Relief)
Low energy

Holoxan 500 Injection Related Warnings

Is the use of Holoxan 500 Injection safe for pregnant women?

Holoxan should not be taken during pregnancy, or should only be taken on the advice of a doctor as it may have severe side effects.

Severe
Is the use of Holoxan 500 Injection safe during breastfeeding?

Holoxan may cause serious side effects in breastfeeding women, so do not take this drug without doctor's advice.

Severe
What is the effect of Holoxan 500 Injection on the Kidneys?

Holoxan may have mild side effects on the kidneys.

Mild
What is the effect of Holoxan 500 Injection on the Liver?

Very few cases of side effects of Holoxan on the liver have been reported.

Mild
What is the effect of Holoxan 500 Injection on the Heart?

Holoxan is completely safe for the heart.

Safe

Severe Interaction of Holoxan 500 Injection with Other Drugs

Holoxan 500 Injection should not be taken with following medicines due to severe side effects it may cause to patients -

Severe

Clozapine

Emtricitabine,Tenofovir,Efavirenz

Amoxicillin,Omeprazole,Clarithromycin

Moderate

Gentamicin

Haloperidol

Holoxan 500 Injection Contraindications

If you are suffering from any of the following diseases, you should not take Holoxan 500 Injection unless your doctor advises you to do so -

Herpes
Infections
Kidney Disease
Liver Disease

Frequently asked Questions about Holoxan 500 Injection

Is this Holoxan 500 Injection habit forming or addictive?

No, there is no any evidence that Holoxan 500 Injection is addictive.

No
Is it safe to drive or operate heavy machinery when consuming?

You may feel sleepy or tired after taking Holoxan 500 Injection. So it is best to avoid driving.

Dangerous
Is it safe?

Holoxan 500 Injection is safe but it is important to consult a doctor before taking it.

Safe, but take only on Doctor's advise
Is it able to treat mental disorders?

No, the use of Holoxan 500 Injection in mental disorders is not effective.

No

Holoxan 500 Injection Interactions with Food and Alcohol

Interaction between Food and Holoxan 500 Injection

It is safe to take Holoxan 500 Injection with food.

Safe
Interaction between Alcohol and Holoxan 500 Injection

Consumption of alcohol and Holoxan 500 Injection together may have severe effects on your health.

Severe

See all substitutes for Holoxan

Celofos 1 Injection - ₹885
Celofos 2 Injection - ₹720
Holoxan Uromitexan 1 Injection 2 Ml - ₹326
Holoxan Uromitexan 2 Injection - ₹867
Holoxan 1 Injection - ₹393
Holoxan 500 Injection - ₹316
Ifopar 1 Injection - ₹470
Ifopar 2 Injection - ₹825
Ipamide 2 Injection - ₹687
Isoxan Injection - ₹425
Soloxan With Mesna Injection - ₹678
Ifosfamide Injection - ₹687
IPOGET 1GM INJECTION - ₹345
Ifowem 1gm Injection - ₹357
Ifowem 2gm Injection - ₹720

This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
7 Years of Experience

References

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 670-671

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 860

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Ifex (ifosfamide)

Therapeutic Goods Administration (TGA): Department of Health [Internet]. Governmet of Australia; Package leaflet information for the user; Holoxan (ifosfamide)

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 670-671

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 860

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Ifex (ifosfamide)

Therapeutic Goods Administration (TGA): Department of Health [Internet]. Governmet of Australia; Package leaflet information for the user; Holoxan (ifosfamide)

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Mesnex (mesna)

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 860, 876

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 822-824

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 670-671

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 860

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Ifex (ifosfamide)

Therapeutic Goods Administration (TGA): Department of Health [Internet]. Governmet of Australia; Package leaflet information for the user; Holoxan (ifosfamide)

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 670-671

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 860

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Ifex (ifosfamide)

Therapeutic Goods Administration (TGA): Department of Health [Internet]. Governmet of Australia; Package leaflet information for the user; Holoxan (ifosfamide)

Holoxan 500 Injection

Holoxan 500 Injection

Holoxan 500 Injection Information

Holoxan 500 Injection Benefits & Uses

Holoxan 500 Injection Dosage & How to Take

Holoxan 500 Injection Side Effects

Holoxan 500 Injection Related Warnings

Severe Interaction of Holoxan 500 Injection with Other Drugs

Holoxan 500 Injection Contraindications

Frequently asked Questions about Holoxan 500 Injection

Holoxan 500 Injection Interactions with Food and Alcohol

See all substitutes for Holoxan

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