Allopurinol



  • Manufactured by:
  • Contains / Salt: Allopurinol


Allopurinol Information



Allopurinol Benefits & Uses

Allopurinol is used to treat the following -

Other Benefits

Allopurinol Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult
  • Disease: Gout
  • Before or After Meal: After Meal
  • Single Maximum Dose: 300 mg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 1 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor
Geriatric
  • Disease: Gout
  • Before or After Meal: After Meal
  • Single Maximum Dose: 300 mg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 1 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor
13 - 18 years (Adolescent)
  • Disease: Gout
  • Before or After Meal: After Meal
  • Single Maximum Dose: 100 mg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 1 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: Dose may increase up to 300 mg
2 - 12 years (Child)
  • Disease: High Uric Acid Levels in the Blood
  • Before or After Meal: After Meal
  • Single Maximum Dose: 100 mg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 1 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor


Allopurinol Side Effects

Based on research, the following side effects have been observed when Allopurinol is used -

Moderate

Mild

Allopurinol Related Warnings

  • Is the use of Allopurinol safe for pregnant women?


    Allopurinol shows severe side effect on pregnant women. For this reason, pregnant women should only take it after taking medical advice.

    Severe
  • Is the use of Allopurinol safe during breastfeeding?


    Breastfeeding women can take Allopurinol as it bears very minor side effects for them.

    Mild
  • What is the effect of Allopurinol on the Kidneys?


    There can be some harmful effects on your kidneys after taking Allopurinol. If you witness any side effects, discontinue its use. Consult your medical practitioner, do as he/she suggests.

    Moderate
  • What is the effect of Allopurinol on the Liver?


    You may experience side effects on your liver after taking Allopurinol. If this happens, then discontinue its use. Consult your medical practitioner, do as he/she suggests.

    Moderate
  • What is the effect of Allopurinol on the Heart?


    Allopurinol has very mild side effects on the heart.

    Mild


Severe Interaction of Allopurinol with Other Drugs

Allopurinol should not be taken with following medicines due to severe side effects it may cause to patients -

Severe

Moderate



Allopurinol Contraindications

If you are suffering from any of the following diseases, you should not take Allopurinol unless your doctor advises you to do so -



Frequently asked Questions about Allopurinol

  • Is this Allopurinol habit forming or addictive?


    Allopurinol does not cause addiction.

    No
  • Is it safe to drive or operate heavy machinery when consuming?


    Yes, you can comfortably use machinery or drive after taking Allopurinol since it will not make you feel sleepy.

    Safe
  • Is it safe?


    Yes, but consume Allopurinol only on doctor's advice.

    Safe, but take only on Doctor's advise
  • Is it able to treat mental disorders?


    No, Allopurinol cannot treat any kind of mental disorder.

    No

Allopurinol Interactions with Food and Alcohol

  • Interaction between Food and Allopurinol


    Some foods when eaten with Allopurinol can alter the onset of actions. Discuss this with your doctor.

    Mild
  • Interaction between Alcohol and Allopurinol


    Taking alcohol with Allopurinol can be dangerous.

    Severe


Frequently asked Questions about Allopurinol

Question almost 4 years ago

Can I take Allopurinol with colchicine?

Dr. MBBS , General Physician, Other, Infectious Disease

Yes, Allopurinol can be taken with colchicine. No drug-drug interaction has been reported between them. It is safe to take Allopurinol along with colchicine if taken as recommended.

Question about 4 years ago

Can I take Allopurinol with diclofenac?

Dr. Abhijit MBBS , General Physician

Yes, Allopurinol can be taken with diclofenac. No drug interaction has been reported between them. However, if you feel any discomfort after taking this drug do not hesitate to inform your doctor.

Question about 5 years ago

What is Allopurinol?

Dr. Amit Singh MBBS , General Physician

Allopurinol is a brand name of allopurinol and it comes in the form of a tablet (solid unit dosage form). It is an antigout agent that belongs to the class of drugs known as xanthine oxidase inhibitors. It is a prescription drug that is used in the treatment of gout (arthritis that causes intense pain and redness in the joints due to deposition of uric acid crystals). Apart from the treatment of gout Allopurinol is given in hyperuricemia and Chemotherapy-induced hyperuricemia (abnormally high levels of uric acid in the blood). It is also given in the treatment of kidney stones.

Question about 5 years ago

Can I discontinue Allopurinol on my own without doctors advice?

Dr. Sameer Awadhiya MBBS , Pediatrics

No, Allopurinol should not be discontinued without doctors advice. You are recommended to always consult a doctor before discontinuing this medicine.

Question about 4 years ago

Is Allopurinol an uricosuric agent?

Dr. B. K. Agrawal MBBS, MD , Cardiology, General Physician, Internal Medicine

No, Allopurinol is not a uricosuric agent which promotes the excretion of uric acid from the body. Allopurinol contains allopurinol which is an antigout agent that belongs to the class of drugs known as xanthine oxidase inhibitors. It decreases the production of uric acid by inhibiting xanthine oxidase enzyme which is essential for the biosynthesis of uric acid.



See all substitutes for Allopurinol


This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience


References

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Zyloprim ® (allopurinol)

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 216-217

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 125-127



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