Axemal

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Axemal Information

Axemal is a prescription medicine that is available as a Tablet. It is primarily used for the treatment of Malaria. Axemal also has some secondary and off-label uses. These are listed below.

The optimal dosage of Axemal is largely dependent on the individual's body weight, medical history, gender and age. Besides the medical condition it is advised for, the route of administration also plays an important role in determining the correct drug dosage. Detailed information has been provided in the dosage section.

While these are the most often observed Axemal side effects, there are can be others also. These have been listed below. These side effects of Axemal are usually temporary and subside with the completion of treatment. However, if these continue for a longer time, consult your doctor right away.

It is also important to note that Axemal has a Mild effect for pregnant women and Moderate effect on lactating mothers. In addition, Axemal's effects on the liver, heart and kidney are discussed below in the Axemal related warnings section.

Axemal can cause adverse effects in certain medical conditions. It is strongly recommended to avoid Axemal in conditions like Porphyria. Other contraindications of Axemal have been discussed in the sections ahead.

Drug interactions for Axemal have been reported in the medical literature. A complete list of these interactions is given below.

In addition to these precautions, you may also note that Axemal is safe while driving, and is is addictive in nature.



Axemal Benefits & Uses

Axemal is used to treat the following -

Other Benefits

Axemal Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult
  • Disease: Lupus
  • Before or After Meal: After Meal
  • Single Maximum Dose: 400 mg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 2 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor
13 - 18 years (Adolescent)
  • Disease: Malaria
  • Before or After Meal: After Meal
  • Single Maximum Dose: 6.5 mg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 1 daily
  • Course Duration: 4 days
  • Special Instructions: This dose for Acute attack, first dose take 13 mg/kg
2 - 12 years (Child)
  • Disease: Malaria
  • Before or After Meal: After Meal
  • Single Maximum Dose: 5 mg/kg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 1 daily
  • Course Duration: 4 days
  • Special Instructions: This dose for Acute attack, first dose take 13 mg/kg
Infant (1 month to 2 years)
  • Disease: Malaria
  • Before or After Meal: After Meal
  • Single Maximum Dose: 5 mg/kg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 1 daily
  • Course Duration: 4 days
  • Special Instructions: This dose for Acute attack, first dose take 13 mg/kg

Axemal Related Warnings

  • Is the use of Axemal safe for pregnant women?


    Axemal rarely shows harmful effects in in pregnant ladies. Even if it does, the effects are mild

    Mild
  • Is the use of Axemal safe during breastfeeding?


    Axemal can cause moderate side effects on breastfeeding women. If you feel its side effects, then stop taking this drug and consult your doctor. Take this medicine again only if your doctor advises to do so.

    Moderate
  • What is the effect of Axemal on the Kidneys?


    Very few cases of side effects of Axemal on kidney have been reported.

    Mild
  • What is the effect of Axemal on the Liver?


    Axemal can have moderate side effects on the liver. If you notice any harmful effects then stop taking this drug right away. Consult your doctor before using this medicine again.

    Moderate
  • What is the effect of Axemal on the Heart?


    Axemal has very mild side effects on the heart.

    Mild


Severe Interaction of Axemal with Other Drugs

Axemal should not be taken with following medicines due to severe side effects it may cause to patients -

Severe



Axemal Contraindications

If you are suffering from any of the following diseases, you should not take Axemal unless your doctor advises you to do so -



Frequently asked Questions about Axemal

  • Is this Axemal habit forming or addictive?


    Axemal does not cause addiction.

    No
  • Is it safe to drive or operate heavy machinery when consuming?


    Axemal does not cause dizziness or sleep, so you can drive a vehicle or operate machinery also.

    Safe
  • Is it safe?


    Axemal is safe but it is important to consult a doctor before taking it.

    Safe, but take only on Doctor's advise
  • Is it able to treat mental disorders?


    Axemal is unable to treat or cure mental disorders.

    No

Axemal Interactions with Food and Alcohol

  • Interaction between Food and Axemal


    There is no information on the effects of taking Axemal with food, because this topic has not been scientifically researched yet.

    Unknown
  • Interaction between Alcohol and Axemal


    Information about the interaction of Axemal and alcohol is not currently available because this topic has not been researched yet.

    Unknown


Frequently asked Questions about Axemal

Question almost 5 years ago

Does Axemal cause low blood pressure?

Dr. Sameer Awadhiya MBBS , Pediatrics

No, Axemal does not cause low blood pressure (hypotension). It has not been reported by the patients who are taking this medicine. It is not a known side effect of this drug. If you are experiencing lightheadedness or blurry vision (symptoms of low blood pressure) after taking this drug then try to sit down and rest for a while till it subsides.

Question about 4 years ago

Can I take Axemal with aspirin?

Dr. Ramraj Meena MBBS , General Physician

Yes Axemal can be taken with paracetamol. Aspirin does not appear to interfere with the efficacy of Axemal. Hence, it is alright to take them together. However, if you feel any discomfort after taking this drug do not hesitate to inform your doctor.

Question about 5 years ago

How long can I safely take Axemal?

Dr. MBBS , General Physician, Other, Infectious Disease

Take Axemal as directed by your doctor. Do not take this medicine longer than prescribed to avoid unpleasant side effects.

Question about 5 years ago

How does Axemal work?

Dr. Anand Singh MBBS , General Physician

Axemal contains hydroxychloroquine. It has antimalarial and immunosuppressant properties. It is presumed that Axemal works by increasing pH in the acid vesicles of parasite which interferes in the parasite's ability to break down and digest hemoglobin. Malarial parasites need hemoglobin for growth and survival. This results in starvation and death of parasites. Axemal works in rheumatoid arthritis and systemic lupus erythematosus (SLE) by suppressing the immune system which provides relief to the patient from pain and inflammation. However, the exact mechanism how Axemal works in autoimmune diseases is still unknown.

Question over 4 years ago

Is Axemal helpful in lupus?

Dr. Vedprakash Verma MBBS, MD , Cardiology

Yes, Axemal is helpful in lupus or systemic lupus erythematosus (SLE). It is used in the treatment of systemic lupus erythematosus (SLE) as well as rheumatoid arthritis. Axemal works in rheumatoid arthritis and systemic lupus erythematosus (SLE) by suppressing the immune system which provides relief to the patient from pain and inflammation. However, the exact mechanism how it works in these autoimmune diseases is still unknown.



See all substitutes for Axemal


This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience


References

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 661-662

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 211

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Plaquenil® (hydroxychloroquine sulfate)



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