Trimine

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  • Contains / Salt: Imipramine (25 mg)
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Trimine Information

Trimine, a prescription drug, is manufactured in various forms such as Tablet. Depression are some of its major therapeutic uses. Secondary and off-label uses of Trimine have also been mentioned below.

The correct dosage of Trimine depends on the patient's age, gender, and medical history. The condition it has been prescribed for, and the route of administration also determine the right dosage. For detailed information on this, read through the dosage section.

Besides the aforementioned side effects, there are other adverse effects of Trimine as well, which are listed below. These side effects of Trimine are usually temporary and subside with the completion of treatment. Please speak with your doctor if these side effects worsen or persist for a longer duration.

Furthermore, you should know that effect of Trimine is Moderate for pregnant women and Severe for women who are breastfeeding. Warnings related to Trimine's effects on the liver, heart and kidney, if any, have been listed below.

Individuals suffering from medical conditions like Heart Disease, Depression must refrain from the use of Trimine since this can cause severe adverse effects. The section on Trimine contraindications lists all such conditions.

Drug reaction of Trimine with other medicines has been reported. Refer to the list below for further details.

Along with the above-mentioned precautions, remember that taking Trimine is considered not safe while driving, and is not addictive.



Trimine Benefits & Uses

Trimine is used to treat the following -

Main Benefits

Other Benefits

Trimine Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult
  • Disease: Depression
  • Before or After Meal: After Meal
  • Single Maximum Dose: 75 mg
  • Dosage Form: Tablet (Immediate Release)
  • Dosage Route: Oral
  • Frequency: 1 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: Dose may be increased up to 150 mg/day
Geriatric
  • Disease: Depression
  • Before or After Meal: After Meal
  • Single Maximum Dose: 40 mg
  • Dosage Form: Tablet (Immediate Release)
  • Dosage Route: Oral
  • Frequency: 1 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor
13 - 18 years (Adolescent)
  • Disease: Depression
  • Before or After Meal: After Meal
  • Single Maximum Dose: 40 mg
  • Dosage Form: Tablet (Immediate Release)
  • Dosage Route: Oral
  • Frequency: 1 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor
2 - 12 years (Child)
  • Disease: Bedwetting
  • Before or After Meal: After Meal
  • Single Maximum Dose: 25 mg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 1 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: given 1 hour prior to bedtime


Trimine Side Effects

Based on research, the following side effects have been observed when Trimine is used -

Severe

  • Rapid heart rate (pulse)

Moderate

Mild

  • Weight gain
  • Dry Mouth
  • Nausea or vomiting
  • Tremor

Trimine Related Warnings

  • Is the use of Trimine safe for pregnant women?


    Trimine can have harmful effects in pregnant women. If you experience any discomfort after using Trimine, then discontinue the use and take your doctor's advice.

    Moderate
  • Is the use of Trimine safe during breastfeeding?


    Trimine should not be taken without taking your doctor's advice, as it may have severe side effects on breastfeeding women.

    Severe
  • What is the effect of Trimine on the Kidneys?


    Trimine has very mild side effects on the kidneys.

    Mild
  • What is the effect of Trimine on the Liver?


    Trimine has very mild side effects on the liver.

    Mild
  • What is the effect of Trimine on the Heart?


    Trimine may have mild side effects on the heart. Most people will never see any effect on the heart.

    Mild


Severe Interaction of Trimine with Other Drugs

Trimine should not be taken with following medicines due to severe side effects it may cause to patients -

Severe

Paracetamol,Chlorpheniramine,Dextromethorphan

    Moderate



    Trimine Contraindications

    If you are suffering from any of the following diseases, you should not take Trimine unless your doctor advises you to do so -



    Frequently asked Questions about Trimine

    • Is this Trimine habit forming or addictive?


      Trimine does not cause addiction.

      No
    • Is it safe to drive or operate heavy machinery when consuming?


      After taking Trimine you may feel sleepy. So it is not advised to perform these activities.

      Dangerous
    • Is it safe?


      Trimine is safe but it is important to consult a doctor before taking it.

      Safe, but take only on Doctor's advise
    • Is it able to treat mental disorders?


      Yes, taking Trimine can treat mental disorders.

      Yes

    Trimine Interactions with Food and Alcohol

    • Interaction between Food and Trimine


      It is safe to take Trimine with food.

      Safe
    • Interaction between Alcohol and Trimine


      Taking Trimine with alcohol can have severely harmful effects on your health.

      Severe


    See all substitutes for Trimine


    This medicine data has been created by -

    Vikas Chauhan

    B.Pharma, Pharmacy
    5 Years of Experience


    References

    April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 679-680

    KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 455-458

    US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Tofranil-PM™ (imipramine pamoate)

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