Digoxin Injection

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Digoxin Injection Information

Digoxin Injection is a commercial drug that is prescribed in the form of Injection. Heart Failure, Arrhythmia are some of its major therapeutic uses. Digoxin Injection also has some secondary and off-label uses. These are listed below.

The right dosage of Digoxin Injection depends on the age, gender, and medical history of the patient. Individual symptoms and route of administration also determines the right dosage. This information has been provided in detail in the dosage section.

Apart from the aforementioned side effects, Digoxin Injection can also lead to other problems, which have been listed below. Such side effects of Digoxin Injection normally do not last long and go away once the treatment is completed. Consult your doctor if these side effects become worse or stay for a longer duration.

In addition, Digoxin Injection's effect is Severe during pregnancy and Safe for lactating mothers. Further, the section on Digoxin Injection related warnings talks about Digoxin Injection's effects on the liver, heart and kidney.

Digoxin Injection is not recommended if you suffer from certain medical conditions as it can have adverse effects. Bradycardia (Slow Heart Rate), Hypercalcemia are examples of such conditions. Some other conditions that can be affected by Digoxin Injection are listed in the contraindications section below.

Drug interactions for Digoxin Injection have been reported in the medical literature. Refer to the list below for further details.

In addition to the above precautions for Digoxin Injection, it is important to know that it is not safe while driving, and is not habit-forming.



Digoxin Injection Benefits & Uses

Digoxin Injection is used to treat the following -

Main Benefits

Other Benefits

Digoxin Injection Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult
  • Disease: Arrhythmia
  • Before or After Meal: Either
  • Single Maximum Dose: 10 mcg/kg
  • Dosage Route: Parenteral
  • Frequency: doctor administered
  • Course Duration: As directed by the doctor
  • Special Instructions: For course duration follow doctor's advice
Geriatric
  • Disease: Arrhythmia
  • Before or After Meal: Either
  • Single Maximum Dose: 10 mcg/kg
  • Dosage Route: Parenteral
  • Frequency: doctor administered
  • Course Duration: As directed by the doctor
  • Special Instructions: For course duration follow doctor's advice
13 - 18 years (Adolescent)
  • Disease: Heart Failure
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 5 mcg/kg
  • Dosage Route: Parenteral
  • Frequency: doctor administered
  • Course Duration: As directed by the doctor
  • Special Instructions: For course duration follow doctor's advice, IM dose are also same
2 - 12 years (Child)
  • Disease: Heart Failure
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 5 mcg/kg
  • Dosage Route: Parenteral
  • Frequency: doctor administered
  • Course Duration: As directed by the doctor
  • Special Instructions: Initially given 17.5 mcg/kg for 3 dose
Neonates (0 to 1 month)
  • Disease: Heart Failure
  • Before or After Meal: Either
  • Single Maximum Dose: 4 mcg/kg
  • Dosage Route: Parenteral
  • Frequency: doctor administered
  • Course Duration: As directed by the doctor
  • Special Instructions: Initially given 17.5 mcg/kg for 3 dose, IM dose are also same
Infant (1 month to 2 years)
  • Disease: Heart Failure
  • Before or After Meal: Either
  • Single Maximum Dose: 6 mcg/kg
  • Dosage Route: Parenteral
  • Frequency: doctor administered
  • Course Duration: As directed by the doctor
  • Special Instructions: Initially given 17.5 mcg/kg for 3 dose, IM dose are also same

Digoxin Injection Related Warnings

  • Is the use of Digoxin Injection safe for pregnant women?


    Digoxin should not be taken during pregnancy, or should only be taken on the advice of a doctor as it may have severe side effects.

    Severe
  • Is the use of Digoxin Injection safe during breastfeeding?


    Breastfeeding women can safely use Digoxin.

    Safe
  • What is the effect of Digoxin Injection on the Kidneys?


    Digoxin rarely affects the kidneys.

    Mild
  • What is the effect of Digoxin Injection on the Liver?


    Information about safety of Digoxin for the liver is not available since scientific research on this is yet to be done.

    Unknown
  • What is the effect of Digoxin Injection on the Heart?


    Digoxin is rarely harmful for the heart.

    Mild


Digoxin Injection Contraindications

If you are suffering from any of the following diseases, you should not take Digoxin Injection unless your doctor advises you to do so -



Frequently asked Questions about Digoxin Injection

  • Is this Digoxin Injection habit forming or addictive?


    Forming a habit of Digoxin Injection has not been reported.

    No
  • Is it safe to drive or operate heavy machinery when consuming?


    No, you should do not do anything that requires concentration and attention as the Digoxin Injection can make you feel drowsy.

    Dangerous
  • Is it safe?


    Digoxin Injection should be used only after doctor's advice.

    Safe, but take only on Doctor's advise
  • Is it able to treat mental disorders?


    There is no benefit of taking Digoxin Injection for mental disorders.

    No

Digoxin Injection Interactions with Food and Alcohol

  • Interaction between Food and Digoxin Injection


    Taking Digoxin Injection with food is safe.

    Safe
  • Interaction between Alcohol and Digoxin Injection


    Information about the interaction of Digoxin Injection and alcohol is not currently available because this topic has not been researched yet.

    Unknown


Frequently asked Questions about Digoxin Injection

Question almost 5 years ago

Can Digoxin cause weight loss?

Dr. OP Kholwad MBBS , General Physician

Yes, Digoxin can cause weight loss if it is taken in higher doses. Weight loss occurs especially in children and older age group (Geriatric). However, if you are experiencing rapid weight loss then discuss it with your doctor instantly.

Question almost 5 years ago

Does Digoxin cause constipation?

Dr. Kapil Sharma MBBS , General Physician

No, Digoxin does not cause constipation. However, if you are experiencing constipation after taking this drug, it may be due to some other medical conditions. Take precautionary methods if you suffer from constipation such as eating fibrous food, drink plenty of fluid, and take some laxative (Lactulose syrup).

Question about 5 years ago

How to take Digoxin?

Dr. B. K. Agrawal MBBS, MD , Cardiology, General Physician, Internal Medicine

Take Digoxin once daily or as advised by your doctor. It can be taken with or without food. Precautions must be taken in patients with hypertension, heart block, and improper kidney function.

Question almost 5 years ago

Can I take Digoxin without consulting a doctor?

Dr. Kuldeep Meena MBBS, MD , Cardiology, Neurology, Pediatrics, Dermatology, Pulmonology, Nephrology, General Physician, Other, Infectious Disease, Emergency Medicine, Allergy and Immunology, Internal Medicine, Multispeciality

No, Digoxin is a high alert and prescription drug so do not take it without consulting a doctor. It can be harmful to the patient to take this medicine without a doctor's recommendation because it can cause very unpleasant side effects. Hence, you should always consult a doctor before taking this medication by himself or herself.

Question almost 5 years ago

Can I take metoprolol and Digoxin together?

Dr. Abhijit MBBS , General Physician

Avoid taking metoprolol and Digoxin together. Because metoprolol might slow the heart rate and increase the chances of side effects. However, if your doctor advises you to take both of these drugs at the same time then you can take them together.



See all substitutes for Digoxin



This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience



References

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 430-433

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 512-519

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Lanoxin® (digoxin)

Therapeutic Goods Administration (TGA): Department of Health [Internet]. Governmet of Australia; Package leaflet information for the user; Sigmaxin (digoxin)

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