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Asginase is a commercial drug that is prescribed in the form of Injection. It is typically used for the treatment of Blood Cancer.
Medical history of the patient along with age and gender determines the dosage of Asginase. Dosage also depends on the route of administration and your chief complaint for which the drug is prescribed. Refer to the dosage section for a detailed discussion.
Asginase also has some side effects, the most common being Rash, Nausea or vomiting, Increased Liver Enzymes. Usually, these side effects of Asginase go away soon, and do not persist beyond the duration of the treatment. However, if these continue for a longer time, consult your doctor right away.
Furthermore, you should know that effect of Asginase is Moderate for pregnant women and Severe for women who are breastfeeding. It is important to know if Asginase has any effect on the kidney, liver and heart. Information on such adverse effects, if any, has been given in the Asginase related warnings section.
Individuals suffering from medical conditions like Bleeding, Pancreatitis must refrain from the use of Asginase since this can cause severe adverse effects. Other contraindications of Asginase have been discussed in the sections ahead.
Drug interactions for Asginase have been reported in the medical literature. See below for a complete list.
You should also be aware that Asginase is not safe while driving, and is not addiction.
Asginase is used to treat the following -
Main Benefits
This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.
Find the right dosage based on disease and age
| Age Group | Dosage |
| 13 - 18 years (Adolescent) |
|
| 2 - 12 years (Child) |
|
Based on research, the following side effects have been observed when Asginase is used -
Common
Is the use of Asginase safe for pregnant women?
Pregnant women may experience moderate side effects from Asginase. It is best to stop taking Asginase immediately and inform your doctor if you notice any discomfort.
Is the use of Asginase safe during breastfeeding?
Women who are breastfeeding may experience severe harmful effects after taking Asginase. It should only be taken after medical advice.
What is the effect of Asginase on the Kidneys?
Asginase has very mild side effects on the kidneys.
What is the effect of Asginase on the Liver?
You may experience side effects on your liver after taking Asginase. If this happens, then discontinue its use. Consult your medical practitioner, do as he/she suggests.
What is the effect of Asginase on the Heart?
You can take Asginase without any fear of damage to the heart.
Asginase should not be taken with following medicines due to severe side effects it may cause to patients -
Severe
Moderate
If you are suffering from any of the following diseases, you should not take Asginase unless your doctor advises you to do so -
Is this Asginase habit forming or addictive?
No, there is no any evidence that Asginase is addictive.
Is it safe to drive or operate heavy machinery when consuming?
After taking Asginase you may feel sleepy. So it is not advised to perform these activities.
Is it safe?
Yes, but consume Asginase only on doctor's advice.
Is it able to treat mental disorders?
There is no benefit of taking Asginase for mental disorders.
Interaction between Food and Asginase
It is safe to take Asginase with food.
Interaction between Alcohol and Asginase
It is difficult to say anything about the effect of Asginase and alcohol. No research has been done on this yet.
This medicine data has been created by -
B.Pharma, Pharmacy
5 Years of Experience
References
US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Elspar® (Asparaginase)
KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 868-869
April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 190-191
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