Crizotinib Benefits & Uses

Crizotinib is used to treat the following -

Other Benefits

Non-Small Cell Lung Cancer

Crizotinib Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group	Dosage
Adult	Disease: Non-Small Cell Lung Cancer Before or After Meal: Either Single Maximum Dose: 250 mg Dosage Form: Capsule Dosage Route: Oral Frequency: 2 daily Course Duration: As directed by the doctor Special Instructions: As prescribed by the doctor
Geriatric	Disease: Non-Small Cell Lung Cancer Before or After Meal: Either Single Maximum Dose: 250 mg Dosage Form: Capsule Dosage Route: Oral Frequency: 2 daily Course Duration: As directed by the doctor Special Instructions: As prescribed by the doctor

Crizotinib Side Effects

Based on research, the following side effects have been observed when Crizotinib is used -

Severe

Nausea or vomiting
Diarrhoea
Edema
Constipation (Read More - Home remedies for constipation)
Dizziness
Fatigue
Decreased white blood cell count (neutrophils)

Moderate

Visual Disturbance

Mild

पेट दर्द
Rash

Common

Altered taste
Decreased appetite

Crizotinib Related Warnings

Is the use of Crizotinib safe for pregnant women?

Crizotinib can cause severe side effects if taken during pregnancy, so, pregnant women should talk to their doctor before taking it.

Severe
Is the use of Crizotinib safe during breastfeeding?

There is no research available on the side effects of Crizotinib in breastfeeding women. Therefore, its impact is unknown.

Unknown
What is the effect of Crizotinib on the Kidneys?

There can be some harmful effects on your kidneys after taking Crizotinib. If you witness any side effects, discontinue its use. Consult your medical practitioner, do as he/she suggests.

Moderate
What is the effect of Crizotinib on the Liver?

Crizotinib can have moderate side effects on the liver. If you notice any harmful effects then stop taking this drug right away. Consult your doctor before using this medicine again.

Moderate
What is the effect of Crizotinib on the Heart?

There may be an adverse effect on the heart after taking Crizotinib. If you observe any side effects on your body then stop taking this drug. Restart this medicine only if your doctor advises you to do so.

Moderate

Severe Interaction of Crizotinib with Other Drugs

Crizotinib should not be taken with following medicines due to severe side effects it may cause to patients -

Severe

Acebutolol

Alfuzosin

Moderate

Codeine

Alfentanil

Aliskiren

Amlodipine

Mild

Albuterol

Albuterol Tablet

Crizotinib Contraindications

If you are suffering from any of the following diseases, you should not take Crizotinib unless your doctor advises you to do so -

Drug Allergy
Bradycardia (Slow Heart Rate)
Liver Disease
Kidney Disease
Pneumonitis
Alcoholism

Frequently asked Questions about Crizotinib

Is this Crizotinib habit forming or addictive?

No, there is no any evidence that Crizotinib is addictive.

No
Is it safe to drive or operate heavy machinery when consuming?

Crizotinib will not make you feel sleepy or drowsy. So you drive or operate machinery safely.

Safe
Is it safe?

Yes, but consume Crizotinib only on doctor's advice.

Safe, but take only on Doctor's advise
Is it able to treat mental disorders?

No, the use of Crizotinib in mental disorders is not effective.

No

Crizotinib Interactions with Food and Alcohol

Interaction between Food and Crizotinib

Due to the absence of research, it is difficult to say how Crizotinib and food will interact.

Unknown
Interaction between Alcohol and Crizotinib

No research has been done on this till date. Therefore, it is not known what the effect of taking Crizotinib with alcohol will be.

Unknown

See all substitutes for Crizotinib

Crizalk 250 Capsule - ₹17711
Crizalk 200 Capsule - ₹97884
Crizotinib Capsule - ₹100000

This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience

References

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Xalkori® (crizotinib)

Crizotinib Capsule - Crizalk 250 Capsule

Crizotinib Information