Crognoc

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Crognoc Information

Crognoc is a monoclonal antibody used in the treatment of various cancers. It works by inhibiting angiogenesis, the process by which tumors develop new blood vessels to sustain their growth. Crognoc specifically binds to vascular endothelial growth factor (VEGF), a protein that promotes the formation of new blood vessels. By neutralizing VEGF, Crognoc starves tumors of their blood supply, inhibiting growth and progression. 

Indications:

  • Colorectal Cancer: Advanced or metastatic stages, often in combination with chemotherapy.
  • Non-Small Cell Lung Cancer (NSCLC): Metastatic cases, in combination with chemotherapy.
  • Renal Cell Carcinoma (RCC): Advanced stages, often combined with interferon alfa.
  • Cervical Cancer: Persistent, recurrent, or metastatic cases.
  • Glioblastoma: As a second-line treatment.
  • Ovarian Cancer: Platinum-resistant and recurrent forms.

Crognoc is a cornerstone in targeted cancer therapy due to its innovative approach to halting tumor growth. However, its use requires careful consideration of patient-specific factors and potential side effects. Collaborating with oncologists and monitoring during treatment ensures the best outcomes for patients.


Crognoc Benefits & Uses

Crognoc is used to treat the following -

Main Benefits

Other Benefits

Crognoc Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult
  • Disease:
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 10 mg/kg
  • Dosage Route: Parenteral
  • Frequency: 2 Weekly
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor
Adult(Female)
  • Disease:
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 10 mg/kg
  • Dosage Route: Parenteral
  • Frequency: 2 Weekly
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor
Geriatric
  • Disease:
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 10 mg/kg
  • Dosage Route: Parenteral
  • Frequency: 2 Weekly
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor

Crognoc Side Effects

Based on research, the following side effects have been observed when Crognoc is used -

Severe

Moderate

Mild

  • Loss of appetite
  • Weight Loss
  • Rhinitis

Common

Unknown

Crognoc Related Warnings

  • Is the use of Crognoc safe for pregnant women?


    Crognoc should not be taken during pregnancy, or should only be taken on the advice of a doctor as it may have severe side effects.

    Severe
  • Is the use of Crognoc safe during breastfeeding?


    Women who are breastfeeding, may experience serious side effects after taking Crognoc. So it is adviced to consult the doctor before using it.

    Severe
  • What is the effect of Crognoc on the Kidneys?


    Crognoc may cause harmful effects on kidney. if you feel its having any such effect, then stop taking this drug, and restart only on your doctor's advice.

    Moderate
  • What is the effect of Crognoc on the Liver?


    The liver can be affected by Crognoc. If you experience any unwanted effects of this drug, stop taking it and consult your doctor. You should restart Crognoc only after medical advice.

    Moderate
  • What is the effect of Crognoc on the Heart?


    Crognoc may cause harmful effects on the heart. if you feel it's having any such effect, then stop taking this drug, and restart only on your doctor's advice.

    Moderate

Severe Interaction of Crognoc with Other Drugs

Crognoc should not be taken with following medicines due to severe side effects it may cause to patients -

Severe

Moderate


Crognoc Contraindications

If you are suffering from any of the following diseases, you should not take Crognoc unless your doctor advises you to do so -


Frequently asked Questions about Crognoc

  • Is this Crognoc habit forming or addictive?


    Crognoc does not cause addiction.

    No
  • Is it safe to drive or operate heavy machinery when consuming?


    No, you should do not do anything that requires concentration and attention as the Crognoc can make you feel drowsy.

    Dangerous
  • Is it safe?


    Crognoc should be used only after doctor's advice.

    Safe, but take only on Doctor's advise
  • Is it able to treat mental disorders?


    Crognoc is unable to treat or cure mental disorders.

    No

Crognoc Interactions with Food and Alcohol

  • Interaction between Food and Crognoc


    It is safe to take Crognoc with food.

    Safe
  • Interaction between Alcohol and Crognoc


    Due to lack of research, there is no information about the side effects of taking Crognoc with alcohol.

    Unknown

See all substitutes for Crognoc


This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
7 Years of Experience


References

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 224-225

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 871

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Avastin® (bevacizumab)

Therapeutic Goods Administration (TGA): Department of Health [Internet]. Governmet of Australia; Package leaflet information for the user; Avastin® (bevacizumab)


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