Domi UP Injection

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Domi UP Injection Information

Domi UP Injection, a prescription drug, is manufactured in various forms such as Injection. It is typically used for the treatment of Nausea and Vomiting.

Medical history of the patient along with age and gender determines the dosage of Domi UP Injection. Dosage also depends on the route of administration and your chief complaint for which the drug is prescribed. For detailed information on this, read through the dosage section.

Apart from the aforementioned side effects, Domi UP Injection can also lead to other problems, which have been listed below. Usually, these side effects of Domi UP Injection go away soon, and do not persist beyond the duration of the treatment. Please speak with your doctor if these side effects worsen or persist for a longer duration.

It is also important to note that Domi UP Injection has a Safe effect for pregnant women and Mild effect on lactating mothers. Further, the section on Domi UP Injection related warnings talks about Domi UP Injection's effects on the liver, heart and kidney.

Domi UP Injection is contraindicated in people with pre-existing medical conditions like Heart Disease, Calcium Deficiency, Potassium Deficiency as it can result in adverse effects. Other contraindications of Domi UP Injection have been discussed in the sections ahead.

Drug interactions for Domi UP Injection have been reported in the medical literature. A complete list of these interactions is given below.

Along with the above-mentioned precautions, remember that taking Domi UP Injection is considered not safe while driving, and is not addictive.



Domi UP Injection Benefits & Uses

Domi UP Injection is used to treat the following -

Domi UP Injection Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult
  • Disease: Nausea and Vomiting
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 0.15 mg/kg
  • Dosage Route: Parenteral
  • Frequency: once only
  • Course Duration: As directed by the doctor
  • Special Instructions: Given 30 minutes prior to the initiation of emetogenic chemotherapy.
Geriatric
  • Disease: Nausea and Vomiting
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 0.15 mg/kg
  • Dosage Route: Parenteral
  • Frequency: once only
  • Course Duration: As directed by the doctor
  • Special Instructions: Given 30 minutes prior to the initiation of emetogenic chemotherapy.
13 - 18 years (Adolescent)
  • Disease: Nausea and Vomiting
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 0.15 mg/kg
  • Dosage Route: Parenteral
  • Frequency: once only
  • Course Duration: As directed by the doctor
  • Special Instructions: Given 30 minutes prior to the initiation of emetogenic chemotherapy.
2 - 12 years (Child)
  • Disease: Nausea and Vomiting
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 0.15 mg/kg
  • Dosage Route: Parenteral
  • Frequency: once only
  • Course Duration: As directed by the doctor
  • Special Instructions: Given 30 minutes prior to the initiation of emetogenic chemotherapy.
Infant (1 month to 2 years)
  • Disease: Nausea and Vomiting
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 0.15 mg/kg
  • Dosage Route: Parenteral
  • Frequency: once only
  • Course Duration: As directed by the doctor
  • Special Instructions: Given 30 minutes prior to the initiation of emetogenic chemotherapy. Given dose older then 6 month

Domi UP Injection Related Warnings

  • Is the use of Domi UP Injection safe for pregnant women?


    Pregnant women can take Domi Up without worrying about any side effects.

    Safe
  • Is the use of Domi UP Injection safe during breastfeeding?


    Domi Up has been seen to have minimal side effects on breastfeeding women.

    Mild
  • What is the effect of Domi UP Injection on the Kidneys?


    There are no side effects of Domi Up on the kidneys.

    Safe
  • What is the effect of Domi UP Injection on the Liver?


    Domi Up can have moderate side effects on the liver. If you notice any harmful effects then stop taking this drug right away. Consult your doctor before using this medicine again.

    Moderate
  • What is the effect of Domi UP Injection on the Heart?


    The heart can be affected by Domi Up. If you experience any unwanted effects of this drug, stop taking it and consult your doctor. You should restart the medicine only after medical advice.

    Moderate


Domi UP Injection Contraindications

If you are suffering from any of the following diseases, you should not take Domi UP Injection unless your doctor advises you to do so -



Frequently asked Questions about Domi UP Injection

  • Is this Domi UP Injection habit forming or addictive?


    Forming a habit of Domi UP Injection has not been reported.

    No
  • Is it safe to drive or operate heavy machinery when consuming?


    You may feel sleepy or tired after taking Domi UP Injection. So it is best to avoid driving.

    Dangerous
  • Is it safe?


    Yes, Domi UP Injection is safe but you must consult your doctor before taking it.

    Safe, but take only on Doctor's advise
  • Is it able to treat mental disorders?


    No, Domi UP Injection cannot treat any kind of mental disorder.

    No

Domi UP Injection Interactions with Food and Alcohol

  • Interaction between Food and Domi UP Injection


    Taking Domi UP Injection with food does not cause any problems.

    Safe
  • Interaction between Alcohol and Domi UP Injection


    Consumption of alcohol and Domi UP Injection together may have severe effects on your health.

    Severe


Frequently asked Questions about Domi UP Injection

Question almost 5 years ago

Is it safe to take Domi Up?

Dr. Vedprakash Verma MBBS, MD , Cardiology

Yes, it is safe to take Domi Up for as long as it is prescribed by your doctor. Do not take more or less of Domi Up, more frequently or less frequently. It is important to follow the recommendations of your doctor completely. 

Question over 5 years ago

What is Domi Up?

Dr Anjum Mujawar MBBS, MBBS , Emergency Medicine

Domi Up is a brand name for ondansetron. It belongs to a class of compounds known as serotonin type 3 receptor antagonists. It is available in the form of tablet and injection. It is used to prevent nausea and vomiting that is caused by anti-cancer drugs, chemotherapy and radiation therapy. It is also used to prevent post-surgical nausea and vomiting. 

Question over 4 years ago

Why Domi Up is prescribed post surgery?

Dr. Yogesh Kumar MBBS , General Physician

Yes, Domi Up is usually administered before and after surgery for treating post-anesthesia shivering (PAS) and nausea. PAS is a condition in which tremors of head, neck, trunk, shoulder, and extremities. It greatly reduces the quality of life of a patient since it causes discomfort and increases pain. It disturbs surgical care and increases the stress on cardiopulmonary functions. Hence as a precautionary measure, this medicine is administered to prevent unpleasant anesthetic effects.

Question about 5 years ago

Is Domi Up an antibiotic?

Dr. Yogesh Kumar MBBS , General Physician

No, Domi Up is not an antibiotic. It is an anti-emetic medication which is used to prevent vomiting associated with chemotherapy and radiation therapy. 

Question about 5 years ago

Does Domi Up cause constipation?

Dr. Ashish Mishra MBBS , Pathology

Yes, Domi Up can cause constipation. Some of the other side effects are a headache and dizziness. Constipation is a debilitating disorder which can be prevented by drinking a lot of water, eating more of fiber, exercising more, taking herbal laxatives, taking probiotic food, and avoiding dairy products. 



See all substitutes for Domi Up



This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience



References

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 947-948

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 668

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Zofran (ondansetron hydrochloride)

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Zofran® (ondansetron hydrochloride)



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