Maclitaxel Information

Maclitaxel is a prescription drug, available for use as Injection. Breast Cancer are some of its major therapeutic uses. Maclitaxel also has some secondary and off-label uses. These are listed below.

Medical history of the patient along with age and gender determines the dosage of Maclitaxel. Dosage also depends on the route of administration and your chief complaint for which the drug is prescribed. For detailed information on this, read through the dosage section.

Besides the aforementioned side effects, there are other adverse effects of Maclitaxel as well, which are listed below. Such side effects of Maclitaxel normally do not last long and go away once the treatment is completed. However, if these continue for a longer time, consult your doctor right away.

Furthermore, you should know that effect of Maclitaxel is Severe for pregnant women and Severe for women who are breastfeeding. In addition, Maclitaxel's effects on the liver, heart and kidney are discussed below in the Maclitaxel related warnings section.

Maclitaxel can cause adverse effects in certain medical conditions. It is strongly recommended to avoid Maclitaxel in conditions like Liver Disease, Herpes, Heart Disease. Other conditions have been mentioned below in the Maclitaxel contraindications section.

Besides this, Maclitaxel may also have severe interaction with some medicines. Refer to the list below for further details.

You should also be aware that Maclitaxel is not safe while driving, and is not addiction.

Maclitaxel Benefits & Uses
Maclitaxel Dosage & How to Take
Maclitaxel Side Effects
Maclitaxel Related Warnings
Severe Interaction of Maclitaxel with Other Drugs
Maclitaxel Contraindications
Frequently asked Questions about Maclitaxel
Maclitaxel Interactions with Food and Alcohol

Maclitaxel Benefits & Uses

Maclitaxel is used to treat the following -

Main Benefits

Breast Cancer

Other Benefits

Non-Small Cell Lung Cancer
Lung Cancer
Ovarian Cancer
Vaginal Cancer

Maclitaxel Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group	Dosage
Adult(Female)	Disease: Breast Cancer Before or After Meal: As advised by a physician Single Maximum Dose: 300 mg Dosage Route: Parenteral Frequency: doctor administered Course Duration: As directed by the doctor Special Instructions: Given in every 3 weeks followed by cisplatin
Adult	Disease: Non-Small Cell Lung Cancer Before or After Meal: As advised by a physician Single Maximum Dose: 225 mg Dosage Route: Parenteral Frequency: doctor administered Course Duration: As directed by the doctor Special Instructions: Given in every 3 weeks followed by cisplatin
Geriatric	Disease: Breast Cancer Before or After Meal: As advised by a physician Single Maximum Dose: 300 mg Dosage Route: Parenteral Frequency: doctor administered Course Duration: As directed by the doctor Special Instructions: Given in every 3 weeks followed by cisplatin

Maclitaxel Related Warnings

Is the use of Maclitaxel safe for pregnant women?

Maclitaxel shows severe side effect on pregnant women. For this reason, pregnant women should only take it after taking medical advice.

Severe
Is the use of Maclitaxel safe during breastfeeding?

Maclitaxel may cause serious side effects in breastfeeding women, so do not take this drug without doctor's advice.

Severe
What is the effect of Maclitaxel on the Kidneys?

There are no side effects of Maclitaxel on the kidneys.

Safe
What is the effect of Maclitaxel on the Liver?

Maclitaxel may cause harmful effects on liver. if you feel it's having any such effect, then stop taking this drug, and restart only on your doctor's advice.

Moderate
What is the effect of Maclitaxel on the Heart?

Side effects of Maclitaxel rarely affect the heart.

Mild

Severe Interaction of Maclitaxel with Other Drugs

Maclitaxel should not be taken with following medicines due to severe side effects it may cause to patients -

Severe

Adalimumab

Clozapine

Etanercept

Ritonavir

Moderate

Emtricitabine,Tenofovir,Efavirenz

Ketoconazole

Maclitaxel Contraindications

If you are suffering from any of the following diseases, you should not take Maclitaxel unless your doctor advises you to do so -

Liver Disease
Herpes
Heart Disease
Peripheral Neuropathy
Infections

Frequently asked Questions about Maclitaxel

Is this Maclitaxel habit forming or addictive?

No, you will not get addicted to Maclitaxel.

No
Is it safe to drive or operate heavy machinery when consuming?

No, you should not drive or operate heavy machinery after taking Maclitaxel as you may feel sleepy.

Dangerous
Is it safe?

Maclitaxel is safe but it is important to consult a doctor before taking it.

Safe, but take only on Doctor's advise
Is it able to treat mental disorders?

Maclitaxel is unable to treat or cure mental disorders.

No

Maclitaxel Interactions with Food and Alcohol

Interaction between Food and Maclitaxel

It is safe to take Maclitaxel with food.

Safe
Interaction between Alcohol and Maclitaxel

Taking Maclitaxel with alcohol can have severely harmful effects on your health.

Severe

See all substitutes for Maclitaxel

This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience

References

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 967-969

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 865-866

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Taxol® (paclitaxel)

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user;Abraxane® (paclitaxel protein-bound particles)

Maclitaxel