Pegstim Information

Pegstim is a prescription drug, available for use as Injection. Neutropenia are some of its major therapeutic uses.

Medical history of the patient along with age and gender determines the dosage of Pegstim. The condition it has been prescribed for, and the route of administration also determine the right dosage. Detailed information has been provided in the dosage section.

The most common side effects of Pegstim are Chills, Cough, Fever. While these are the most often observed Pegstim side effects, there are can be others also. These have been listed below. Such side effects of Pegstim normally do not last long and go away once the treatment is completed. If, however, they worsen or do not go away, please speak with your physician.

Pegstim's effect during pregnancy is Moderate and Unknown while nursing. It is important to know if Pegstim has any effect on the kidney, liver and heart. Information on such adverse effects, if any, has been given in the Pegstim related warnings section.

Pegstim can cause adverse effects in certain medical conditions. It is strongly recommended to avoid Pegstim in conditions like Blood Cancer, Kidney Disease. Other contraindications of Pegstim have been discussed in the sections ahead.

Additionally, Pegstim may also adversely react with other medicines. Refer to the list below for further details.

Along with the above-mentioned precautions, remember that taking Pegstim is considered safe while driving, and is addictive.

Pegstim Benefits & Uses
Pegstim Dosage & How to Take
Pegstim Side Effects
Pegstim Related Warnings
Severe Interaction of Pegstim with Other Drugs
Pegstim Contraindications
Frequently asked Questions about Pegstim
Pegstim Interactions with Food and Alcohol

Pegstim Benefits & Uses

Pegstim is used to treat the following -

Other Benefits

Neutropenia

Pegstim Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group	Dosage
Adult	Disease: Neutropenia Before or After Meal: As advised by a physician Single Maximum Dose: 6 mg Dosage Route: Parenteral Frequency: doctor administered Course Duration: As directed by the doctor Special Instructions: once per chemotherapy cycle, beginning at least 24 hours after completion of chemotherapy
13 - 18 years (Adolescent)	Disease: Neutropenia Before or After Meal: As advised by a physician Single Maximum Dose: 6 mg Dosage Route: Parenteral Frequency: doctor administered Course Duration: As directed by the doctor Special Instructions: once per chemotherapy cycle, beginning at least 24 hours after completion of chemotherapy
Geriatric	Disease: Neutropenia Before or After Meal: As advised by a physician Single Maximum Dose: 6 mg Dosage Route: Parenteral Frequency: doctor administered Course Duration: As directed by the doctor Special Instructions: once per chemotherapy cycle, beginning at least 24 hours after completion of chemotherapy, weighing 45 kg or more
2 - 12 years (Child)	Disease: Neutropenia Before or After Meal: As advised by a physician Single Maximum Dose: 1.5 mg Dosage Route: Parenteral Frequency: doctor administered Course Duration: As directed by the doctor Special Instructions: Infants and Children weighing 10 to 20 kg
Infant (1 month to 2 years)	Disease: Neutropenia Before or After Meal: As advised by a physician Single Maximum Dose: 0.1 mg/kg Dosage Route: Parenteral Frequency: doctor administered Course Duration: As directed by the doctor Special Instructions: Neonates and Infants weighing less than 10 kg

Pegstim Related Warnings

Is the use of Pegstim safe for pregnant women?

Pregnant women may experience moderate side effects from Pegstim. It is best to stop taking Pegstim immediately and inform your doctor if you notice any discomfort.

Moderate
Is the use of Pegstim safe during breastfeeding?

In the absence of any scientific study about the side effects of Pegstim in breastfeeding women, information on safety of Pegstim is unavailable.

Unknown
What is the effect of Pegstim on the Kidneys?

Very few cases of side effects of Pegstim on kidney have been reported.

Mild
What is the effect of Pegstim on the Liver?

Pegstim is not harmful for the liver.

Safe
What is the effect of Pegstim on the Heart?

You may experience side effects on your heart after taking Pegstim. If this happens, then discontinue its use. Consult your medical practitioner, and do as he/she suggests.

Moderate

Severe Interaction of Pegstim with Other Drugs

Pegstim should not be taken with following medicines due to severe side effects it may cause to patients -

Moderate

Pegstim Contraindications

If you are suffering from any of the following diseases, you should not take Pegstim unless your doctor advises you to do so -

Drug Allergy
Sickle Cell Crisis
Blood Cancer
Respiratory Distress Syndrome
Sickle Cell Disease
Kidney Disease

Frequently asked Questions about Pegstim

Is this Pegstim habit forming or addictive?

No, there is no any evidence that Pegstim is addictive.

No
Is it safe to drive or operate heavy machinery when consuming?

Yes, you can comfortably use machinery or drive after taking Pegstim since it will not make you feel sleepy.

Safe
Is it safe?

Pegstim should be used only after doctor's advice.

Safe, but take only on Doctor's advise
Is it able to treat mental disorders?

No, the use of Pegstim in mental disorders is not effective.

No

Pegstim Interactions with Food and Alcohol

Interaction between Food and Pegstim

Due to a lack of research, nothing can be said about the consequences of taking Pegstim together with food.

Unknown
Interaction between Alcohol and Pegstim

It is difficult to say anything about the effect of Pegstim and alcohol. No research has been done on this yet.

Unknown

See all substitutes for Pegstim

This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience

References

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 994

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Neulasta® (pegfilgrastim)

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Fulphila™ (pegfilgrastim-jmdb)

Therapeutic Goods Administration (TGA): Department of Health [Internet]. Governmet of Australia; Package leaflet information for the user; Tezmota® (pegfilgrastim)

Pegstim