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What is neutropenia?

Neutropenia is a condition in which there are decreased levels of neutrophils in the blood. A neutrophil is a type of white blood cell formed in the bone marrow, which protects your body against infections by fighting germs. If the levels of neutrophils fall below 1500 per microlitre of blood, you are said to be neutropenic.

People having neutropenia are at increased risk of developing infections due to a weakened immune system.

What are its main signs and symptoms?

There are no specific symptoms associated with neutropenia. It is typically detected when an infection occurs. Symptoms commonly seen in case of infections are:

What are the main causes?

Cancer therapy is one of the main causes of neutropenia. It includes chemotherapy (with medicines), radiotherapy (with radiation) and biotherapy (with substances obtained from living organisms). These therapies destroy both the rapidly growing cancer cells and normal cells because they cannot differentiate between the two. Other causes include:

How is it diagnosed and treated?

Your doctor will recommend a blood test to assess the levels of neutrophils in the blood. If the cause of neutropenia is not clear, your doctor will suggest a bone marrow test to diagnose any disorders of the bone marrow.

Treatment for neutropenia varies depending on the cause. In case of infection, antibiotics are prescribed. In chemotherapy, the neutrophil count generally falls within the first 2 weeks of treatment and reaches a normal range again by 3 to 4 weeks. If there is a failure to achieve normal values, therapy is initiated with growth factors, which stimulate bone marrow to produce white blood cells. It is an expensive treatment, making accessibility difficult.

  1. Medicines for Neutropenia

Medicines for Neutropenia

Medicines listed below are available for Neutropenia. Please note that you should not take any medicines without doctor consultation. Taking any medicine without doctor's consultation can cause serious problems.

Medicine NamePack SizePrice (Rs.)
Rite O CefRITE O CEFF DRY SYRUP 30ML44
ExtacefEXTACEF 100MG TABLET 10S70
CeftasCEFTAS 400MG TABLET 10S195
MiliximMILIXIM 100MG DS SYRUP 30ML53
ZifiZIFI 100MG DRY SYRUP 50ML117
Rite O Cef CvRite O Cef Cv 200 Mg/125 Mg Tablet216
GrafeelGRAFEEL 30MIO U INJECTION1115
Gramocef CvGramocef Cv 200 Mg/125 Mg Tablet236
Taxim OTAXIM O 100MG TABLET 10S95
Ritolide 250 Mg TabletRitolide 250 Mg Tablet168
PeggrafeelPeggrafeel 6 Mg Injection7144
RevobactoRevobacto 200 Mg/200 Mg Tablet156
PidPid 200 Mg Tablet72
TraxofTraxof 100 Mg/100 Mg Tablet Dt52
Qucef (Dr Cure)Qucef 200 Mg Tablet Dt93
Vicocef OVicocef O Tablet159
QuixQuix 1000 Mg Injection51
Vilcocef OVilcocef O Tablet79
Quix CdQuix Cd 100 Mg Tablet43
Zeefix OxZeefix Ox Tablet96
RaximRaxim 250 Mg Tablet230
R CefiR Cefi 100 Mg Tablet100
Zifi O TabletZifi O 100 Mg/100 Mg Tablet Dt72
Recef ORECEF O DT 100MG TABLET 10S0
Abcef OAbcef O 200 Mg/200 Mg Tablet91

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References

  1. American Society of Clinical Oncology. Neutropenia. Virginia, United States; [Internet]
  2. Kalpathi Krishnaman et al. Epedimiologic, clinical profile and factors affecting the outcome in febrile neutropenia . South Asian J Cancer. 2017 Jan-Mar; 6(1): 25–27. PMID: 28413792
  3. Merck Manual Consumer Version [Internet]. Kenilworth (NJ): Merck & Co. Neutropenia.
  4. National Cancer Institute [Internet]. Bethesda (MD): U.S. Department of Health and Human Services; Infection and Neutropenia during Cancer Treatment
  5. MedlinePlus Medical Encyclopedia: US National Library of Medicine; Neutropenia - infants
  6. MedlinePlus Medical Encyclopedia: US National Library of Medicine; Low white blood cell count and cancer
  7. healthdirect Australia. Neutropenia. Australian government: Department of Health
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