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Tacrolimus is a prescription medicine. Liver transplant, Kidney transplant, Heart Transplant are some of its major therapeutic uses. Other than this, Tacrolimus has some other therapeutic uses, which have been discussed ahead.
The correct dosage of Tacrolimus depends on the patient's age, gender, and medical history. The condition it has been prescribed for, and the route of administration also determine the right dosage. This information has been provided in detail in the dosage section.
Besides the aforementioned side effects, there are other adverse effects of Tacrolimus as well, which are listed below. Such side effects of Tacrolimus normally do not last long and go away once the treatment is completed. However, if these continue for a longer time, consult your doctor right away.
Furthermore, you should know that effect of Tacrolimus is Moderate for pregnant women and Moderate for women who are breastfeeding. It is important to know if Tacrolimus has any effect on the kidney, liver and heart. Information on such adverse effects, if any, has been given in the Tacrolimus related warnings section.
Individuals suffering from medical conditions like Infections, Diabetes Type 2 must refrain from the use of Tacrolimus since this can cause severe adverse effects. Other conditions have been mentioned below in the Tacrolimus contraindications section.
Besides this, Tacrolimus may also have severe interaction with some medicines. See below for a complete list.
You should also be aware that Tacrolimus is safe while driving, and is addiction.
Tacrolimus is used to treat the following -
Main Benefits
Other Benefits
This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.
Find the right dosage based on disease and age
| Age Group | Dosage |
| Adult |
|
| Geriatric |
|
| 13 - 18 years (Adolescent) |
|
| 2 - 12 years (Child) |
|
Based on research, the following side effects have been observed when Tacrolimus is used -
Moderate
Mild
Is the use of Tacrolimus safe for pregnant women?
Pregnant women may experience moderate side effects from Tacrolimus. It is best to stop taking Tacrolimus immediately and inform your doctor if you notice any discomfort.
Is the use of Tacrolimus safe during breastfeeding?
Breastfeeding women may feel side effects of Tacrolimus. If you see any side effects, stop taking Tacrolimus immediately and talk to your doctor. Take Tacrolimus again, only after your doctor's advice.
What is the effect of Tacrolimus on the Kidneys?
There may be some adverse effects on kidney after taking Tacrolimus. If you observe any such side effects, stop taking this drug. Consume this medicine again only if your doctor advises you to do so.
What is the effect of Tacrolimus on the Liver?
The liver can be affected by Tacrolimus. If you experience any unwanted effects of this drug, stop taking it and consult your doctor. You should restart Tacrolimus only after medical advice.
What is the effect of Tacrolimus on the Heart?
Tacrolimus can cause side effects that could harm the heart. So medical advice before taking it is necessary.
Tacrolimus should not be taken with following medicines due to severe side effects it may cause to patients -
Severe
Moderate
If you are suffering from any of the following diseases, you should not take Tacrolimus unless your doctor advises you to do so -
Is this Tacrolimus habit forming or addictive?
No, you will not get addicted to Tacrolimus.
Is it safe to drive or operate heavy machinery when consuming?
Tacrolimus does not cause dizziness or sleep, so you can drive a vehicle or operate machinery also.
Is it safe?
Yes, but take Tacrolimus only as per medical advice.
Is it able to treat mental disorders?
No, Tacrolimus cannot treat any kind of mental disorder.
Interaction between Food and Tacrolimus
Due to a lack of research, nothing can be said about the consequences of taking Tacrolimus together with food.
Interaction between Alcohol and Tacrolimus
Consumption of alcohol and Tacrolimus together may have severe effects on your health.
This medicine data has been created by -
References
US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Prograf® (tacrolimus)
KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 881
April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 1165-1167
US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Prograf® (tacrolimus)
KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 881
April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 1165-1167
