Tacrolimus



  • Manufactured by:
  • Contains / Salt: Tacrolimus


Tacrolimus Information

Tacrolimus is a prescription medicine. Liver transplant, Kidney transplant, Heart Transplant are some of its major therapeutic uses. Other than this, Tacrolimus has some other therapeutic uses, which have been discussed ahead.

The correct dosage of Tacrolimus depends on the patient's age, gender, and medical history. The condition it has been prescribed for, and the route of administration also determine the right dosage. This information has been provided in detail in the dosage section.

Besides the aforementioned side effects, there are other adverse effects of Tacrolimus as well, which are listed below. Such side effects of Tacrolimus normally do not last long and go away once the treatment is completed. However, if these continue for a longer time, consult your doctor right away.

Furthermore, you should know that effect of Tacrolimus is Moderate for pregnant women and Moderate for women who are breastfeeding. It is important to know if Tacrolimus has any effect on the kidney, liver and heart. Information on such adverse effects, if any, has been given in the Tacrolimus related warnings section.

Individuals suffering from medical conditions like Infections, Diabetes Type 2 must refrain from the use of Tacrolimus since this can cause severe adverse effects. Other conditions have been mentioned below in the Tacrolimus contraindications section.

Besides this, Tacrolimus may also have severe interaction with some medicines. See below for a complete list.

You should also be aware that Tacrolimus is safe while driving, and is addiction.



Tacrolimus Benefits & Uses

Tacrolimus is used to treat the following -

Main Benefits

Other Benefits

Tacrolimus Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult
  • Disease: Atopic Dermatitis
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: Apply in appropriate quantity on affected area
  • Dosage Form: Ointment
  • Dosage Route: Topical
  • Frequency: 2 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: For course duration follow doctor's advice
Geriatric
  • Disease: Atopic Dermatitis
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: Apply in appropriate quantity on affected area
  • Dosage Form: Ointment
  • Dosage Route: Topical
  • Frequency: 2 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: For course duration follow doctor's advice
13 - 18 years (Adolescent)
  • Disease: Atopic Dermatitis
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: Apply in appropriate quantity on affected area
  • Dosage Form: Ointment
  • Dosage Route: Topical
  • Frequency: 2 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: For course duration follow doctor's advice
2 - 12 years (Child)
  • Disease: Atopic Dermatitis
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: Apply in appropriate quantity on affected area
  • Dosage Form: Ointment
  • Dosage Route: Topical
  • Frequency: 2 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: For course duration follow doctor's advice

Tacrolimus Related Warnings

  • Is the use of Tacrolimus safe for pregnant women?


    Pregnant women may experience moderate side effects from Tacrolimus. It is best to stop taking Tacrolimus immediately and inform your doctor if you notice any discomfort.

    Moderate
  • Is the use of Tacrolimus safe during breastfeeding?


    Breastfeeding women may feel side effects of Tacrolimus. If you see any side effects, stop taking Tacrolimus immediately and talk to your doctor. Take Tacrolimus again, only after your doctor's advice.

    Moderate
  • What is the effect of Tacrolimus on the Kidneys?


    There may be some adverse effects on kidney after taking Tacrolimus. If you observe any such side effects, stop taking this drug. Consume this medicine again only if your doctor advises you to do so.

    Moderate
  • What is the effect of Tacrolimus on the Liver?


    The liver can be affected by Tacrolimus. If you experience any unwanted effects of this drug, stop taking it and consult your doctor. You should restart Tacrolimus only after medical advice.

    Moderate
  • What is the effect of Tacrolimus on the Heart?


    Use of Tacrolimus may be dangerous for the heart. Do not use it without doctor's advice.

    Severe


Severe Interaction of Tacrolimus with Other Drugs

Tacrolimus should not be taken with following medicines due to severe side effects it may cause to patients -

Severe

Moderate



Tacrolimus Contraindications

If you are suffering from any of the following diseases, you should not take Tacrolimus unless your doctor advises you to do so -



Frequently asked Questions about Tacrolimus

  • Is this Tacrolimus habit forming or addictive?


    No, you will not get addicted to Tacrolimus.

    No
  • Is it safe to drive or operate heavy machinery when consuming?


    Yes, you can operate a vehicle or heavy machinery after taking Tacrolimus since it does not cause drowsiness.

    Safe
  • Is it safe?


    Yes, Tacrolimus is safe but you must consult your doctor before taking it.

    Safe, but take only on Doctor's advise
  • Is it able to treat mental disorders?


    There is no benefit of taking Tacrolimus for mental disorders.

    No

Tacrolimus Interactions with Food and Alcohol

  • Interaction between Food and Tacrolimus


    There is no information on the effects of taking Tacrolimus with food, because this topic has not been scientifically researched yet.

    Unknown
  • Interaction between Alcohol and Tacrolimus


    Consuming Tacrolimus with alcohol can have many serious effects on your body.

    Severe


Frequently asked Questions about Tacrolimus

Question about 4 years ago

Can I take Tacrolimus with Clarithromycin?

Dr. Anand Singh MBBS , General Physician

No, you cannot take the Tacrolimus with clarithromycin, as it may change the effect of the Tacrolimus and cause some serious side effects, always consult your doctor before taking this drug combination.

Question about 5 years ago

How does Tacrolimus work?

Dr. Vinod Verma MBBS , Diabetology

Tacrolimus work by reducing the activity of the immune system so it cannot attack the transplanted organ. Hence in this way, it prevents the rejection of organ transplants.

Question almost 5 years ago

How long can I safely use Tacrolimus?

Dr. B. K. Agrawal MBBS, MD , Cardiology, General Physician, Internal Medicine

Take Tacrolimus as advised by your doctor. Do not discontinue the drug suddenly or take it longer than prescribed by your doctor.

Question almost 5 years ago

Can I discontinue Tacrolimus on my own without doctors advice?

Dr. Braj Bhushan Ojha BAMS , Gastroenterology, Dermatology, Psychiatry, Ayurveda, Sexology, Diabetology

Yes, you can discontinue the Tacrolimus once you get the relief from burns. You are recommended to consult a doctor before discontinuing this medicine.

Question about 5 years ago

What is Tacrolimus?

Dr. Kuldeep Meena MBBS, MD , Cardiology, Neurology, Pediatrics, Dermatology, Pulmonology, Nephrology, General Physician, Other, Infectious Disease, Emergency Medicine, Allergy and Immunology, Internal Medicine, Multispeciality

Tacrolimus is a brand name of tacrolimus and it is available in the form of a capsule, granules for oral suspension, an extended-release tablet, injectables, and ointment. It belongs to the class of drugs known as immunosuppressants. Tacrolimus is a prescription drug that is used to prevent the rejection of organ transplants (liver and kidney). The topical form of Tacrolimus is used to treat eczema. 



See all substitutes for Tacrolimus


This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience


References

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Prograf® (tacrolimus)

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 881

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 1165-1167

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