Trigem

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  • Manufactured by: Medley Pharmaceuticals
  • Contains / Salt: Glimepiride (1 mg) + Metformin (500 mg) + Pioglitazone (15 mg)

Trigem Information

Trigem is a commercial drug that is prescribed in the form of Tablet. Diabetes are some of its major therapeutic uses. Trigem also has some secondary and off-label uses. These are listed below.

The optimal dosage of Trigem is largely dependent on the individual's body weight, medical history, gender and age. Dosage also depends on the route of administration and your chief complaint for which the drug is prescribed. Detailed information has been provided in the dosage section.

Common side effects of Trigem include Nausea or vomiting, Diarrhoea, Headache. Some other side effects of Trigem have been listed ahead. Such side effects of Trigem normally do not last long and go away once the treatment is completed. Please speak with your doctor if these side effects worsen or persist for a longer duration.

In addition, Trigem's effect is Unknown during pregnancy and Safe for lactating mothers. In addition, Trigem's effects on the liver, heart and kidney are discussed below in the Trigem related warnings section.

Trigem is contraindicated in people with pre-existing medical conditions like Liver Disease, Kidney Disease as it can result in adverse effects.

Drug interactions for Trigem have been reported in the medical literature. See below for a complete list.

You should also be aware that Trigem is not safe while driving, and is not addiction.


Trigem Benefits & Uses

Trigem is used to treat the following -

Main Benefits

Other Benefits

  • Diabetes Type 2

Trigem Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult
  • Disease:
  • Before or After Meal: With meal
  • Single Maximum Dose: 1 Tablet
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 1 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: strength 15 mg pioglitazone, 1 mg glimepiride and 500 mg metformin
Geriatric
  • Disease:
  • Before or After Meal: With meal
  • Single Maximum Dose: 1 Tablet
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 1 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: strength 15 mg pioglitazone, 1 mg glimepiride and 500 mg metformin

Trigem Side Effects

Based on research, the following side effects have been observed when Trigem is used -

Severe

  • Hypoglycemia (Low blood sugar level)

Common

Trigem Related Warnings

  • Is the use of Trigem safe for pregnant women?


    No research has been done to ascertain the safety of Trigem in pregnant women. If you are pregnant, it is best to ask a doctor to know if you can take it.

    Unknown
  • Is the use of Trigem safe during breastfeeding?


    Breastfeeding women can safely use Trigem.

    Safe
  • What is the effect of Trigem on the Kidneys?


    There can be some harmful effects on your kidneys after taking Trigem. If you witness any side effects, discontinue its use. Consult your medical practitioner, do as he/she suggests.

    Moderate
  • What is the effect of Trigem on the Liver?


    Trigem may cause harmful effects on liver. if you feel it's having any such effect, then stop taking this drug, and restart only on your doctor's advice.

    Moderate
  • What is the effect of Trigem on the Heart?


    Trigem is rarely harmful for the heart.

    Mild

Severe Interaction of Trigem with Other Drugs

Trigem should not be taken with following medicines due to severe side effects it may cause to patients -

Severe


Trigem Contraindications

If you are suffering from any of the following diseases, you should not take Trigem unless your doctor advises you to do so -


Frequently asked Questions about Trigem

  • Is this Trigem habit forming or addictive?


    No, there is no any evidence that Trigem is addictive.

    No
  • Is it safe to drive or operate heavy machinery when consuming?


    No, you should do not do anything that requires concentration and attention as the Trigem can make you feel drowsy.

    Dangerous
  • Is it safe?


    Yes, but take Trigem only as per medical advice.

    Safe, but take only on Doctor's advise
  • Is it able to treat mental disorders?


    No, Trigem is not used to treat mental disorders.

    No

Trigem Interactions with Food and Alcohol

  • Interaction between Food and Trigem


    Due to a lack of research, nothing can be said about the consequences of taking Trigem together with food.

    Unknown
  • Interaction between Alcohol and Trigem


    It is difficult to say anything about the effect of Trigem and alcohol. No research has been done on this yet.

    Unknown

See all substitutes for Trigem


This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
7 Years of Experience


References

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Amaryl (glimepiride)

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 272

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 1156-1158

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Glucophage® (metformin hydrochloride)

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 275-276

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 825-826

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Actos (pioglitazone hydrochloride)

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 276-277

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 1032-1033

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