Zondel 400/250 Tablet

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Zondel 400/250 Tablet Information

Zondel 400/250 Tablet is a prescription drug, available for use as Tablet. Nausea and Vomiting are some of its major therapeutic uses.

The optimal dosage of Zondel 400/250 Tablet is largely dependent on the individual's body weight, medical history, gender and age. The condition it has been prescribed for, and the route of administration also determine the right dosage. This information has been provided in detail in the dosage section.

Apart from the aforementioned side effects, Zondel 400/250 Tablet can also lead to other problems, which have been listed below. Usually, these side effects of Zondel 400/250 Tablet go away soon, and do not persist beyond the duration of the treatment. Consult your doctor if these side effects become worse or stay for a longer duration.

In addition, Zondel 400/250 Tablet's effect is Safe during pregnancy and Mild for lactating mothers. In addition, Zondel 400/250 Tablet's effects on the liver, heart and kidney are discussed below in the Zondel 400/250 Tablet related warnings section.

Zondel 400/250 Tablet is contraindicated in people with pre-existing medical conditions like Heart Disease, Calcium Deficiency, Potassium Deficiency as it can result in adverse effects. Other contraindications of Zondel 400/250 Tablet have been discussed in the sections ahead.

Additionally, Zondel 400/250 Tablet may also adversely react with other medicines. See below for a complete list.

In addition to these precautions, you may also note that Zondel 400/250 Tablet is not safe while driving, and is is not addictive in nature.



Zondel 400/250 Tablet Benefits & Uses

Zondel 400/250 Tablet is used to treat the following -

Zondel 400/250 Tablet Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult
  • Disease: Nausea and Vomiting
  • Before or After Meal: Either
  • Single Maximum Dose: 8 mg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 2 daily
  • Course Duration: 2 days
  • Special Instructions: Give first dose 30 minutes before the start of emetogenic chemotherapy
Geriatric
  • Disease: Nausea and Vomiting
  • Before or After Meal: Either
  • Single Maximum Dose: 8 mg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 2 daily
  • Course Duration: 2 days
  • Special Instructions: Give first dose 30 minutes before the start of emetogenic chemotherapy
13 - 18 years (Adolescent)
  • Disease: Nausea and Vomiting
  • Before or After Meal: Either
  • Single Maximum Dose: 8 mg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 2 daily
  • Course Duration: 5 days
  • Special Instructions: Give first dose 30 minutes before the start of emetogenic chemotherapy
2 - 12 years (Child)
  • Disease: Nausea and Vomiting
  • Before or After Meal: Either
  • Single Maximum Dose: 4 mg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 3 daily
  • Course Duration: 5 days
  • Special Instructions: Give first dose 30 minutes before the start of emetogenic chemotherapy

Zondel 400/250 Tablet Related Warnings

  • Is the use of Zondel 400/250 Tablet safe for pregnant women?


    Pregnant women can take Zondel safely.

    Safe
  • Is the use of Zondel 400/250 Tablet safe during breastfeeding?


    Zondel may have very limited harmful effects for breastfeeding women.

    Mild
  • What is the effect of Zondel 400/250 Tablet on the Kidneys?


    Zondel is not harmful for kidneys.

    Safe
  • What is the effect of Zondel 400/250 Tablet on the Liver?


    There may be an adverse effect on the liver after taking Zondel. If you observe any side effects on your body then stop taking this drug. Take this medicine again only if your doctor advises you to do so.

    Moderate
  • What is the effect of Zondel 400/250 Tablet on the Heart?


    The heart can be affected by Zondel. If you experience any unwanted effects of this drug, stop taking it and consult your doctor. You should restart the medicine only after medical advice.

    Moderate


Zondel 400/250 Tablet Contraindications

If you are suffering from any of the following diseases, you should not take Zondel 400/250 Tablet unless your doctor advises you to do so -



Frequently asked Questions about Zondel 400/250 Tablet

  • Is this Zondel 400/250 Tablet habit forming or addictive?


    No, there is no any evidence that Zondel 400/250 Tablet is addictive.

    No
  • Is it safe to drive or operate heavy machinery when consuming?


    After taking Zondel 400/250 Tablet you may feel sleepy. So it is not advised to perform these activities.

    Dangerous
  • Is it safe?


    Zondel 400/250 Tablet is safe but it is important to consult a doctor before taking it.

    Safe, but take only on Doctor's advise
  • Is it able to treat mental disorders?


    No, Zondel 400/250 Tablet is not used to treat mental disorders.

    No

Zondel 400/250 Tablet Interactions with Food and Alcohol

  • Interaction between Food and Zondel 400/250 Tablet


    Taking Zondel 400/250 Tablet with food does not harm your health.

    Safe
  • Interaction between Alcohol and Zondel 400/250 Tablet


    Consumption of alcohol and Zondel 400/250 Tablet together may have severe effects on your health.

    Severe


Frequently asked Questions about Zondel 400/250 Tablet

Question about 5 years ago

Is Zondel an antibiotic?

Dr. Yogesh Kumar MBBS , General Physician

No, Zondel is not an antibiotic. It is an anti-emetic medication which is used to prevent vomiting associated with chemotherapy and radiation therapy. 

Question almost 5 years ago

Is it safe to take Zondel?

Dr. Vedprakash Verma MBBS, MD , Cardiology

Yes, it is safe to take Zondel for as long as it is prescribed by your doctor. Do not take more or less of Zondel, more frequently or less frequently. It is important to follow the recommendations of your doctor completely. 

Question almost 5 years ago

Can Zondel be taken with tramadol?

Dr. Braj Bhushan Ojha BAMS , Gastroenterology, Dermatology, Psychiatry, Ayurveda, Sexology, Diabetology

No, Zondel should not be ideally taken with tramadol as the action of both the drugs decreases upon concomitant use. Tramadol is an opioid medication used to treat mild to moderate pain. Take it only when a doctor has prescribed it. ​

Question over 4 years ago

Why Zondel is prescribed post surgery?

Dr. Yogesh Kumar MBBS , General Physician

Yes, Zondel is usually administered before and after surgery for treating post-anesthesia shivering (PAS) and nausea. PAS is a condition in which tremors of head, neck, trunk, shoulder, and extremities. It greatly reduces the quality of life of a patient since it causes discomfort and increases pain. It disturbs surgical care and increases the stress on cardiopulmonary functions. Hence as a precautionary measure, this medicine is administered to prevent unpleasant anesthetic effects.

Question over 5 years ago

How does Zondel work?

Dr. Uday Nath Sahoo MBBS , Internal Medicine

Zondel belongs to a class of compounds known as 5 -HT3 receptor antagonists. It blocks the action of serotonin completely at the 5-HT3 receptor sites present in our brain (vomiting centre) which provides relief to the patient from nausea and vomiting.



See all substitutes for Zondel



This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience



References

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 947-948

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 668

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Zofran (ondansetron hydrochloride)

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Zofran® (ondansetron hydrochloride)

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