Megarest

1 Injection in 1 Packet Out of Stock
₹ 69
1 INJECTION 1 Packet ₹ 69
  • Out of Stock

  • Manufactured by:
  • Contains / Salt: Midazolam (10 mg)
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Megarest Information

Megarest is a prescription drug, available for use as Injection. It is primarily used for the treatment of Anesthesia. Secondary and off-label uses of Megarest have also been mentioned below.

The correct dosage of Megarest depends on the patient's age, gender, and medical history. The condition it has been prescribed for, and the route of administration also determine the right dosage. For detailed information on this, read through the dosage section.

Megarest also has some side effects, the most common being Headache, Hiccup, Cough. While these are the most often observed Megarest side effects, there are can be others also. These have been listed below. Normally, these side effects of Megarest are not long lasting and go away when the treatment is finished. Please speak with your doctor if these side effects worsen or persist for a longer duration.

In addition, Megarest's effect is Severe during pregnancy and Mild for lactating mothers. It is important to know if Megarest has any effect on the kidney, liver and heart. Information on such adverse effects, if any, has been given in the Megarest related warnings section.

Megarest is not recommended if you suffer from certain medical conditions as it can have adverse effects. Dementia, Allergy are examples of such conditions. Other conditions have been mentioned below in the Megarest contraindications section.

Besides this, Megarest may also have severe interaction with some medicines. Refer to the list below for further details.

Along with the above-mentioned precautions, remember that taking Megarest is considered not safe while driving, and is not addictive.



Megarest Benefits & Uses

Megarest is used to treat the following -

Main Benefits

Other Benefits

Megarest Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult
  • Disease: Anesthesia
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 0.2 mg/kg
  • Dosage Route: Parenteral
  • Frequency: once only
  • Course Duration: 1 days
  • Special Instructions: As prescribed by the doctor
13 - 18 years (Adolescent)
  • Disease: Anesthesia
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 1 mcg/kg/min
  • Dosage Route: Parenteral
  • Frequency: once only
  • Course Duration: 1 days
  • Special Instructions: As prescribed by the doctor
2 - 12 years (Child)
  • Disease: Anesthesia
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 1 mcg/kg/min
  • Dosage Route: Parenteral
  • Frequency: once only
  • Course Duration: 1 days
  • Special Instructions: As prescribed by the doctor
Infant (1 month to 2 years)
  • Disease: Anesthesia
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 1 mcg/kg/min
  • Dosage Route: Parenteral
  • Frequency: once only
  • Course Duration: 1 days
  • Special Instructions: 0.5 mcg/kg/min dose should be administer to patients less than 32 weeks old


Megarest Side Effects

Based on research, the following side effects have been observed when Megarest is used -

Severe

Moderate

  • Agitation
  • Erythema
  • Hallucinations
  • Blurred vision

Mild

Common

Megarest Related Warnings

  • Is the use of Megarest safe for pregnant women?


    Pregnant women may get severe side effects after taking Megarest. If you are pregnant, do not take Megarest without a doctor's advice.

    Severe
  • Is the use of Megarest safe during breastfeeding?


    Side effects of Megarest on breastfeeding women are very mild.

    Mild
  • What is the effect of Megarest on the Kidneys?


    Megarest has very mild side effects on the kidneys.

    Mild
  • What is the effect of Megarest on the Liver?


    Megarest is rarely harmful for the liver.

    Mild
  • What is the effect of Megarest on the Heart?


    Side effects of Megarest rarely affect the heart.

    Mild


Severe Interaction of Megarest with Other Drugs

Megarest should not be taken with following medicines due to severe side effects it may cause to patients -

Severe

Moderate



Megarest Contraindications

If you are suffering from any of the following diseases, you should not take Megarest unless your doctor advises you to do so -



Frequently asked Questions about Megarest

  • Is this Megarest habit forming or addictive?


    Megarest can be addictive. You should not take it without medical advice.

    Yes
  • Is it safe to drive or operate heavy machinery when consuming?


    After taking Megarest, you should not drive or work on any heavy machine, as Megarest can make you drowsy.

    Dangerous
  • Is it safe?


    Yes, but avoid taking more than the amount of Megarest prescribed by your doctor.

    translation missing: en.yes-but-only-in-limited-use
  • Is it able to treat mental disorders?


    Megarest has been seen to have positive effect on patients with mental disorders.

    Yes

Megarest Interactions with Food and Alcohol

  • Interaction between Food and Megarest


    Some foods when eaten with Megarest can alter the onset of actions. Discuss this with your doctor.

    Mild
  • Interaction between Alcohol and Megarest


    Taking Megarest with alcohol can have severely harmful effects on your health.

    Severe


Frequently asked Questions about Megarest

Question about 5 years ago

How to take Megarest?

Dr. R.K Singh MBBS , Diabetology

Megarest must be taken under the medical supervision only. Precautions must be taken in patients with respiratory disorders, and improper kidney or liver function.

Question over 4 years ago

Does Megarest cause nausea & vomiting?

Dr. Uday Nath Sahoo MBBS , Internal Medicine

Yes, Megarest may cause nausea and vomiting. It is a rare side effect of this drug. However, the exact cause behind nausea and vomiting is not known.

Question almost 5 years ago

Can Megarest cause urinary retention?

Dr. MBBS , General Physician, Other, Obstetrics & Gynaecology

No, Megarest does not cause urinary retention. It has not been reported by the patients who are taking this drug. 

Question over 4 years ago

Can I take seroquel and Megarest together?

Dr. Saurabh Shakya MBBS , General Physician

Yes, you can take seroquel (quetiapine) and Megarest together only on your doctor's advice because taking this drug along with seroquel increases the risk of side effects such as drowsiness (sedation), dizziness, confusion, and difficulty in concentrating.   

Question about 5 years ago

How does Megarest work?

Dr. Haleema Yezdani MBBS , General Physician

Megarest contains midazolam that works by increasing the activity of a chemical messenger GABA (gamma-aminobutyric acid) which suppresses the excessive activity of nerve cells in the brain and induces sedation.



See all substitutes for Megarest


This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience


References

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 854-856

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 383

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Nayzilam® (midazolam)

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; – Hypnovel® (midazolam)

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