Topotec

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Topotec Information

Topotec is a prescription drug, available for use as Injection. It is typically used for the treatment of Ovarian Cancer. The alternative uses of Topotec have also been explained below.

The optimal dosage of Topotec is largely dependent on the individual's body weight, medical history, gender and age. Individual symptoms and route of administration also determines the right dosage. This information has been provided in detail in the dosage section.

Topotec also has some side effects, the most common being Fatigue, Nausea or vomiting, Headache. Besides the aforementioned side effects, there are other adverse effects of Topotec as well, which are listed below. Such side effects of Topotec normally do not last long and go away once the treatment is completed. If, however, they worsen or do not go away, please speak with your physician.

Furthermore, you should know that effect of Topotec is Severe for pregnant women and Severe for women who are breastfeeding. In addition, Topotec's effects on the liver, heart and kidney are discussed below in the Topotec related warnings section.

Topotec is contraindicated in people with pre-existing medical conditions like Anemia, Herpes, Lung Cancer as it can result in adverse effects.

Additionally, Topotec may also adversely react with other medicines. See below for a complete list.

In addition to these precautions, you may also note that Topotec is not safe while driving, and is is not addictive in nature.



Topotec Benefits & Uses

Topotec is used to treat the following -

Other Benefits

Topotec Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult(Female)
  • Disease: Ovarian Cancer
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 2.5 mg
  • Dosage Route: Parenteral
  • Frequency: 1 daily
  • Course Duration: 3 weeks
  • Special Instructions: Given for 5 consecutive days, starting on day 1 of a 21 day course, 1.5 mg/ m(2)
Adult
  • Disease: Small Cell Lung Cancer
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 2.5 mg
  • Dosage Route: Parenteral
  • Frequency: 1 daily
  • Course Duration: 3 weeks
  • Special Instructions: Given for 5 consecutive days, starting on day 1 of a 21 day course, 1.5 mg/ m(2)
Geriatric
  • Disease: Small Cell Lung Cancer
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 2.5 mg
  • Dosage Route: Parenteral
  • Frequency: 1 daily
  • Course Duration: 3 weeks
  • Special Instructions: Given for 5 consecutive days, starting on day 1 of a 21 day course, 1.5 mg/ m(2)

Topotec Related Warnings

  • Is the use of Topotec safe for pregnant women?


    Topotec can cause severe side effects if taken during pregnancy, so, pregnant women should talk to their doctor before taking it.

    Severe
  • Is the use of Topotec safe during breastfeeding?


    Topotec should not be taken without taking your doctor's advice, as it may have severe side effects on breastfeeding women.

    Severe
  • What is the effect of Topotec on the Kidneys?


    Topotec rarely harms the kidneys.

    Mild
  • What is the effect of Topotec on the Liver?


    Topotec does not damage the liver.

    Safe
  • What is the effect of Topotec on the Heart?


    Topotec is not harmful for the heart.

    Safe


Severe Interaction of Topotec with Other Drugs

Topotec should not be taken with following medicines due to severe side effects it may cause to patients -

Severe



Topotec Contraindications

If you are suffering from any of the following diseases, you should not take Topotec unless your doctor advises you to do so -



Frequently asked Questions about Topotec

  • Is this Topotec habit forming or addictive?


    Topotec does not cause addiction.

    No
  • Is it safe to drive or operate heavy machinery when consuming?


    No, you should not drive or operate heavy machinery after taking Topotec as you may feel sleepy.

    Dangerous
  • Is it safe?


    Yes, but take Topotec only as per medical advice.

    Safe, but take only on Doctor's advise
  • Is it able to treat mental disorders?


    No, Topotec cannot treat any kind of mental disorder.

    No

Topotec Interactions with Food and Alcohol

  • Interaction between Food and Topotec


    Taking Topotec with food is safe.

    Safe
  • Interaction between Alcohol and Topotec


    It is difficult to say anything about the effect of Topotec and alcohol. No research has been done on this yet.

    Unknown


See all substitutes for Topotec


This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience


References

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Topotecan

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 1221-1223

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 866



In stock alternatives of Topotec (based on Topotecan (2.5 mg))

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