Rational Plus

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  • Contains / Salt: Ofloxacin (200 mg) + Ornidazole (500 mg)
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Rational Plus Information

Rational Plus is a commercial drug that is prescribed in the form of Tablet. Other than this, Rational Plus has some other therapeutic uses, which have been discussed ahead.

The right dosage of Rational Plus depends on the age, gender, and medical history of the patient. The condition it has been prescribed for, and the route of administration also determine the right dosage. This information has been provided in detail in the dosage section.

The most common side effects of Rational Plus are Abdominal Pain, Nausea or vomiting, Skin Rash. Apart from the aforementioned side effects, Rational Plus can also lead to other problems, which have been listed below. Normally, these side effects of Rational Plus are not long lasting and go away when the treatment is finished. If, however, they worsen or do not go away, please speak with your physician.

Rational Plus's effect during pregnancy is Moderate and Moderate while nursing. Warnings related to Rational Plus's effects on the liver, heart and kidney, if any, have been listed below.

Individuals suffering from medical conditions like Heart Disease, Stomach Disease must refrain from the use of Rational Plus since this can cause severe adverse effects. The section on Rational Plus contraindications lists all such conditions.

Drug reaction of Rational Plus with other medicines has been reported. See below for a complete list.

You should also be aware that Rational Plus is safe while driving, and is addiction.



Rational Plus Benefits & Uses

Rational Plus is used to treat the following -

Other Benefits

Rational Plus Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
13 - 18 years (Adolescent)
  • Disease: Diarrhoea (Loose Motions)
  • Before or After Meal: Either
  • Single Maximum Dose: 1 Tablet
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 2 daily
  • Course Duration: 5 days
  • Special Instructions: Dosage strength: Ofloxacin (200 mg), Ornidazole (500 mg)/Tablet
2 - 12 years (Child)
  • Disease: Diarrhoea (Loose Motions)
  • Before or After Meal: Either
  • Single Maximum Dose: 1 Tablet
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 2 daily
  • Course Duration: 5 days
  • Special Instructions: Dosage strength: Ofloxacin (100 mg), Ornidazole (250 mg)/Tablet, dose for children 8 - 12 years old
Adult
  • Disease: Diarrhoea (Loose Motions)
  • Before or After Meal: Either
  • Single Maximum Dose: 1 Tablet
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 2 daily
  • Course Duration: 5 days
  • Special Instructions: Dosage strength: Ofloxacin (200 mg), Ornidazole (500 mg)/Tablet
Geriatric
  • Disease: Diarrhoea (Loose Motions)
  • Before or After Meal: Either
  • Single Maximum Dose: 1 Tablet
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 2 daily
  • Course Duration: 5 days
  • Special Instructions: Dosage strength: Ofloxacin (200 mg), Ornidazole (500 mg)/Tablet

Rational Plus Related Warnings

  • Is the use of Rational Plus safe for pregnant women?


    Rational Plus may cause moderate side effects during pregnancy. If you feel its harmful effects, then stop taking this drug immediately, and do not take Rational Plus again without your doctor's advice.

    Moderate
  • Is the use of Rational Plus safe during breastfeeding?


    If you are breastfeeding, you may experience some harmful effects of Rational Plus. In case you experience any of these, discontinue its use until you consult your doctor.

    Moderate
  • What is the effect of Rational Plus on the Kidneys?


    There are no side effects of Rational Plus on the kidneys.

    Safe
  • What is the effect of Rational Plus on the Liver?


    Rational Plus may cause harmful effects on liver. if you feel it's having any such effect, then stop taking this drug, and restart only on your doctor's advice.

    Moderate
  • What is the effect of Rational Plus on the Heart?


    There may be an adverse effect on the heart after taking Rational Plus. If you observe any side effects on your body then stop taking this drug. Restart this medicine only if your doctor advises you to do so.

    Moderate


Severe Interaction of Rational Plus with Other Drugs

Rational Plus should not be taken with following medicines due to severe side effects it may cause to patients -

Severe

Moderate



Rational Plus Contraindications

If you are suffering from any of the following diseases, you should not take Rational Plus unless your doctor advises you to do so -



Frequently asked Questions about Rational Plus

  • Is this Rational Plus habit forming or addictive?


    No, there is no any evidence that Rational Plus is addictive.

    No
  • Is it safe to drive or operate heavy machinery when consuming?


    Yes, you can comfortably use machinery or drive after taking Rational Plus since it will not make you feel sleepy.

    Safe
  • Is it safe?


    Yes, Rational Plus is safe but you must consult your doctor before taking it.

    Safe, but take only on Doctor's advise
  • Is it able to treat mental disorders?


    No, Rational Plus cannot treat any kind of mental disorder.

    No

Rational Plus Interactions with Food and Alcohol

  • Interaction between Food and Rational Plus


    Taking Rational Plus with food does not harm your health.

    Safe
  • Interaction between Alcohol and Rational Plus


    Consumption of alcohol and Rational Plus together may have severe effects on your health.

    Severe


Frequently asked Questions about Rational Plus

Question about 5 years ago

Does Rational Plus cause stomach upset?

Dr. Chinmaya Bal MBBS , General Physician

Yes, [medicine] can cause stomach upset. It is a common side effect of this drug. Please inform your doctor if you are experiencing severe stomach upset after taking this medicine.

Question over 4 years ago

Can I take Rational Plus with metformin?

Take Rational Plus if your doctor has prescribed it to you. However, keep a close check on blood sugar levels as metformin is known to cause hypoglycemia( sudden dip in blood sugar levels). In case you are experiencing severe hypoglycemia, please inform your doctor immediately.

Question almost 5 years ago

Is Rational Plus safe?

Dr. Surender Kumar MBBS , General Physician

Yes, Rational Plus is safe to use, if taken in the prescribed amount and duration as advised by the doctor. However, certain side effects have been associated with this drug such as stomach pain, nausea, diarrhea, headache, difficulty in breathing, and constipation.

Question over 4 years ago

Does Rational Plus contain penicillin?

Dr. Haleema Yezdani MBBS , General Physician

No, Rational Plus does not contain penicillin. It is an antibiotic that belongs to the class of medication called fluoroquinolone. It used to treat several types of bacterial infection such as such as bronchitis, pneumonia, urinary, respiratory, skin, gastrointestinal, anthrax, bone, and eye infections.

Question about 5 years ago

How does Rational Plus works?

Dr. Ramraj MBBS , Other

Rational Plus is a broad-spectrum antibiotic, active against both Gram-positive and Gram-negative bacteria. It works by inhibiting the bacterial cell division and stops the working of enzyme which is responsible for cell division. It is effective against a large number of bacteria, even those bacteria which are resistant to other drugs.



See all substitutes for Rational Plus


This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience


References

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 1400

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 713

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Floxin® (ofloxacin)

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Ocuflox® (ofloxacin)

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 839

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