Mitomycin

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Mitomycin Information

Mitomycin is a prescription drug, available for use as Injection, Ampules. Primarily, it is used for the treatment of Pancreatic Cancer. The alternative uses of Mitomycin have also been explained below.

The optimal dosage of Mitomycin is largely dependent on the individual's body weight, medical history, gender and age. Besides the medical condition it is advised for, the route of administration also plays an important role in determining the correct drug dosage. Refer to the dosage section for a detailed discussion.

The most common side effects of Mitomycin are Loss of appetite, Pain or discomfort. Besides the aforementioned side effects, there are other adverse effects of Mitomycin as well, which are listed below. Usually, these side effects of Mitomycin go away soon, and do not persist beyond the duration of the treatment. Consult your doctor if these side effects become worse or stay for a longer duration.

It is also important to note that Mitomycin has a Severe effect for pregnant women and Severe effect on lactating mothers. Further, the section on Mitomycin related warnings talks about Mitomycin's effects on the liver, heart and kidney.

Mitomycin is not recommended if you suffer from certain medical conditions as it can have adverse effects. Neutropenia are examples of such conditions. Some other conditions that can be affected by Mitomycin are listed in the contraindications section below.

Drug interactions for Mitomycin have been reported in the medical literature. See below for a complete list.

Along with the above-mentioned precautions, remember that taking Mitomycin is considered not safe while driving, and is not addictive.



Mitomycin Benefits & Uses

Mitomycin is used to treat the following -

Main Benefits

Other Benefits

Mitomycin Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult
  • Disease: Pancreatic Cancer
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 40 mg
  • Dosage Route: Parenteral
  • Frequency: doctor administered
  • Course Duration: As directed by the doctor
  • Special Instructions: Given 20 mg/m² IV every 6-8 Weeks
Geriatric
  • Disease: Pancreatic Cancer
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 40 mg
  • Dosage Route: Parenteral
  • Frequency: doctor administered
  • Course Duration: As directed by the doctor
  • Special Instructions: Given 20 mg/m² IV every 6-8 Weeks


Mitomycin Side Effects

Based on research, the following side effects have been observed when Mitomycin is used -

Severe

  • Decreased white blood cell count (neutrophils)
  • Reduced blood platelets

Moderate

Mild

Common

  • Loss of appetite
  • Pain or discomfort

Mitomycin Related Warnings

  • Is the use of Mitomycin safe for pregnant women?


    Mitomycin should not be taken during pregnancy, or should only be taken on the advice of a doctor as it may have severe side effects.

    Severe
  • Is the use of Mitomycin safe during breastfeeding?


    Mitomycin should not be taken without taking your doctor's advice, as it may have severe side effects on breastfeeding women.

    Severe
  • What is the effect of Mitomycin on the Kidneys?


    There may be some adverse effects on kidney after taking Mitomycin. If you observe any such side effects, stop taking this drug. Consume this medicine again only if your doctor advises you to do so.

    Moderate
  • What is the effect of Mitomycin on the Liver?


    Mitomycin does not damage the liver.

    Safe
  • What is the effect of Mitomycin on the Heart?


    Very few cases of side effects of Mitomycin on the heart have been reported.

    Mild


Severe Interaction of Mitomycin with Other Drugs

Mitomycin should not be taken with following medicines due to severe side effects it may cause to patients -

Severe

Moderate



Mitomycin Contraindications

If you are suffering from any of the following diseases, you should not take Mitomycin unless your doctor advises you to do so -



Frequently asked Questions about Mitomycin

  • Is this Mitomycin habit forming or addictive?


    Forming a habit of Mitomycin has not been reported.

    No
  • Is it safe to drive or operate heavy machinery when consuming?


    You may feel sleepy or tired after taking Mitomycin. So it is best to avoid driving.

    Dangerous
  • Is it safe?


    Yes, Mitomycin is safe but you must consult your doctor before taking it.

    Safe, but take only on Doctor's advise
  • Is it able to treat mental disorders?


    No, Mitomycin is not used to treat mental disorders.

    No

Mitomycin Interactions with Food and Alcohol

  • Interaction between Food and Mitomycin


    You can take Mitomycin with food.

    Safe
  • Interaction between Alcohol and Mitomycin


    No research has been done on this till date. Therefore, it is not known what the effect of taking Mitomycin with alcohol will be.

    Unknown


See all substitutes for Mitomycin


This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience


References

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 868-869

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 868

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Mitosol® (mitomycin)



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