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Sifotaxim 500 Injection is a prescription medicine that is available as a Injection. Meningitis are some of its major therapeutic uses. Sifotaxim 500 Injection also has some secondary and off-label uses. These are listed below.
The correct dosage of Sifotaxim 500 Injection depends on the patient's age, gender, and medical history. Dosage also depends on the route of administration and your chief complaint for which the drug is prescribed. For detailed information on this, read through the dosage section.
Besides the aforementioned side effects, there are other adverse effects of Sifotaxim 500 Injection as well, which are listed below. Such side effects of Sifotaxim 500 Injection normally do not last long and go away once the treatment is completed. Consult your doctor if these side effects become worse or stay for a longer duration.
Furthermore, you should know that effect of Sifotaxim 500 Injection is Safe for pregnant women and Safe for women who are breastfeeding. Warnings related to Sifotaxim 500 Injection's effects on the liver, heart and kidney, if any, have been listed below.
Sifotaxim 500 Injection can cause adverse effects in certain medical conditions. It is strongly recommended to avoid Sifotaxim 500 Injection in conditions like Kidney Disease. Other conditions have been mentioned below in the Sifotaxim 500 Injection contraindications section.
Drug reaction of Sifotaxim 500 Injection with other medicines has been reported. See below for a complete list.
In addition to the above precautions for Sifotaxim 500 Injection, it is important to know that it is not safe while driving, and is not habit-forming.
Sifotaxim 500 Injection is used to treat the following -
Other Benefits
This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.
Find the right dosage based on disease and age
| Age Group | Dosage |
| Adult |
|
| Geriatric |
|
| 13 - 18 years (Adolescent) |
|
| 2 - 12 years (Child) |
|
| Neonates (0 to 1 month) |
|
Based on research, the following side effects have been observed when Sifotaxim 500 Injection is used -
Severe
Moderate
Mild
Is the use of Sifotaxim 500 Injection safe for pregnant women?
Sifotaxim is safe for pregnant women.
Is the use of Sifotaxim 500 Injection safe during breastfeeding?
Sifotaxim does not show any side effects in breastfeeding women.
What is the effect of Sifotaxim 500 Injection on the Kidneys?
Sifotaxim may have mild side effects on the kidneys.
What is the effect of Sifotaxim 500 Injection on the Liver?
Sifotaxim does not damage the liver.
What is the effect of Sifotaxim 500 Injection on the Heart?
Sifotaxim is not harmful for the heart.
Sifotaxim 500 Injection should not be taken with following medicines due to severe side effects it may cause to patients -
Moderate
If you are suffering from any of the following diseases, you should not take Sifotaxim 500 Injection unless your doctor advises you to do so -
Is this Sifotaxim 500 Injection habit forming or addictive?
Forming a habit of Sifotaxim 500 Injection has not been reported.
Is it safe to drive or operate heavy machinery when consuming?
After taking Sifotaxim 500 Injection, you should not drive or work on any heavy machine, as Sifotaxim 500 Injection can make you drowsy.
Is it safe?
Sifotaxim 500 Injection is safe but it is important to consult a doctor before taking it.
Is it able to treat mental disorders?
No, Sifotaxim 500 Injection is not used to treat mental disorders.
Interaction between Food and Sifotaxim 500 Injection
Taking Sifotaxim 500 Injection with food is safe.
Interaction between Alcohol and Sifotaxim 500 Injection
No research has been done on this till date. Therefore, it is not known what the effect of taking Sifotaxim 500 Injection with alcohol will be.
Sifotaxim is a broad-spectrum antibiotic which is active against both Gram-positive and Gram-negative bacteria. It works by preventing the cell wall synthesis in bacteria by binding to specific proteins (penicillin-binding proteins). The cell wall protects the bacteria from the environment, in the absence of this cell wall, the bacteria becomes vulnerable and dies. Sifotaxim is effective against a wide range of both gram negative and gram positive bacteria such as Escherichia coli, Haemophilus influenza, Staphylococcus aureus, and Staphylococcus pneumonia.
The dosage of this drug may vary from case to case as it depends on the type of infection and severity of an infection. You are recommended to take this drug as per your doctor's instructions. Precautions must be taken in patients with a history of penicillin allergy, colitis, and impaired kidney function.
Yes, Sifotaxim can be taken with paracetamol. No harmful drug interaction has been reported between them. However, if you feel any discomfort after taking this drug do not hesitate to inform your doctor and follow his/her instructions.
Yes, Sifotaxim is used to treat meningitis caused by Neisseria meningitides. It works by preventing the cell wall synthesis in bacteria by binding to specific proteins (penicillin-binding proteins). The cell wall protects the bacteria from the environment, in the absence of this cell wall, the bacteria becomes vulnerable and dies.
Yes, Sifotaxim covers anaerobes. It is effective against some of the anaerobic bacteria such as Bacteroides spp, Clostridium spp, Fusobacterium spp, Peptococcus spp, and Peptostreptococcus spp.
This medicine data has been created by -
B.Pharma, Pharmacy
7 Years of Experience
References
KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 727
US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Claforan® (cefotaxime)