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Espra XN 375 Tablet is a prescription medicine that is available as a Tablet. Secondary and off-label uses of Espra XN 375 Tablet have also been mentioned below.
The optimal dosage of Espra XN 375 Tablet is largely dependent on the individual's body weight, medical history, gender and age. Individual symptoms and route of administration also determines the right dosage. Detailed information has been provided in the dosage section.
The most common side effects of Espra XN 375 Tablet are Belching, Bruising or discoloration. Besides the aforementioned side effects, there are other adverse effects of Espra XN 375 Tablet as well, which are listed below. Normally, these side effects of Espra XN 375 Tablet are not long lasting and go away when the treatment is finished. If, however, they worsen or do not go away, please speak with your physician.
Espra XN 375 Tablet's effect during pregnancy is Moderate and Severe while nursing. Further, the section on Espra XN 375 Tablet related warnings talks about Espra XN 375 Tablet's effects on the liver, heart and kidney.
Individuals suffering from medical conditions like Kidney Disease, Asthma must refrain from the use of Espra XN 375 Tablet since this can cause severe adverse effects. Some other conditions that can be affected by Espra XN 375 Tablet are listed in the contraindications section below.
Additionally, Espra XN 375 Tablet may also adversely react with other medicines. A complete list of these interactions is given below.
In addition to these precautions, you may also note that Espra XN 375 Tablet is safe while driving, and is is addictive in nature.
Espra XN 375 Tablet is used to treat the following -
Other Benefits
This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.
Find the right dosage based on disease and age
| Age Group | Dosage |
| 13 - 18 years (Adolescent) |
|
| Adult |
|
| Geriatric |
|
Based on research, the following side effects have been observed when Espra XN 375 Tablet is used -
Moderate
Mild
Common
Is the use of Espra XN 375 Tablet safe for pregnant women?
Espra XN may have some side effects during pregnancy. Pregnant women should discontinue the use of Espra XN, and talk to their doctor, if they notice any discomfort.
Is the use of Espra XN 375 Tablet safe during breastfeeding?
Taking Espra XN may lead to serious side effects if you are breastfeeding. Espra XN should not be taken by breastfeeding women unless prescribed by the doctor.
What is the effect of Espra XN 375 Tablet on the Kidneys?
Using Espra XN does not have any harmful effects on kidneys.
What is the effect of Espra XN 375 Tablet on the Liver?
Espra XN has very mild side effects on the liver.
What is the effect of Espra XN 375 Tablet on the Heart?
Using Espra XN does not have any harmful effects on the heart.
Espra XN 375 Tablet should not be taken with following medicines due to severe side effects it may cause to patients -
Severe
Moderate
If you are suffering from any of the following diseases, you should not take Espra XN 375 Tablet unless your doctor advises you to do so -
Is this Espra XN 375 Tablet habit forming or addictive?
Forming a habit of Espra XN 375 Tablet has not been reported.
Interaction between Food and Espra XN 375 Tablet
Taking Espra XN 375 Tablet with food does not harm your health.
Interaction between Alcohol and Espra XN 375 Tablet
Consuming Espra XN 375 Tablet with alcohol can have many serious effects on your body.
Espra XN can be taken 1-2 times in a day or as advised by your doctor. It can be taken with food or milk to avoid nausea and other stomach related problem. Precautions must be taken in patients with heart diseases, peptic ulcer, and improper liver or kidney function. You should strictly take this drug if prescribed only.
Espra XN is a prescription drug, hence do not take it without consulting doctor. It can be harmful to the patients to take this medicine without a doctor's advice.
Espra XN contains naproxen (which is a pain-killer) that works by reversibly inhibiting enzymes (cyclooxygenase-1 and -2 also known as COX-1 and -2) which produces prostaglandin. Prostaglandin is presumed to be responsible for causing pain and inflammation in the body. Inhibition of these enzymes results in decreased synthesis of prostaglandins which provides relief to the patient from pain and inflammation caused by arthritis and ankylosing spondylitis.
Yes, Espra XN is a pain-killer because it contains naproxen that belongs to the class of nonsteroidal anti-inflammatory drugs (NSAIDs) which possess analgesic (pain-killer) activity. It works by reversibly inhibiting enzymes (cyclooxygenase-1 and -2 also known as COX-1 and -2) which produces prostaglandins. Prostaglandins are responsible for causing pain in the body. Inhibition of these enzymes results in decreased synthesis of prostaglandins which provides relief to the patient from pain.
Yes, Espra XN is safe to use, if taken in prescribed amount and duration as advised by the doctor. However, certain side effects have been associated with this drug such as abdominal pain, drowsiness, and flatulence. If you experience above-mentioned side effects after taking this medicine then inform your doctor and follow his/her instructions.
This medicine data has been created by -
B.Pharma, Pharmacy
7 Years of Experience
References
April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 893-894
KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 201
US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Naprelan® (naproxen sodium)
US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Naprosyn® (naproxen)
US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Naprosyn® (naproxen)
US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Nexium (esomeprazole magnesium)
KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 653
April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 524-526