Zybev

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4ml Injection in 1 Vial Out of Stock
₹ 19200
4ml Injection 1 Vial ₹ 19200

  • Manufactured by: Zydus Cadila
  • Contains / Salt: Bevacizumab

Zybev Information

Zybev is a monoclonal antibody used in the treatment of various cancers. It works by inhibiting angiogenesis, the process by which tumors develop new blood vessels to sustain their growth. Zybev specifically binds to vascular endothelial growth factor (VEGF), a protein that promotes the formation of new blood vessels. By neutralizing VEGF, Zybev starves tumors of their blood supply, inhibiting growth and progression. 

Indications:

  • Colorectal Cancer: Advanced or metastatic stages, often in combination with chemotherapy.
  • Non-Small Cell Lung Cancer (NSCLC): Metastatic cases, in combination with chemotherapy.
  • Renal Cell Carcinoma (RCC): Advanced stages, often combined with interferon alfa.
  • Cervical Cancer: Persistent, recurrent, or metastatic cases.
  • Glioblastoma: As a second-line treatment.
  • Ovarian Cancer: Platinum-resistant and recurrent forms.

Zybev is a cornerstone in targeted cancer therapy due to its innovative approach to halting tumor growth. However, its use requires careful consideration of patient-specific factors and potential side effects. Collaborating with oncologists and monitoring during treatment ensures the best outcomes for patients.


Zybev Benefits & Uses

Zybev is used to treat the following -

Main Benefits

Other Benefits

Zybev Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult
  • Disease:
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 10 mg/kg
  • Dosage Route: Parenteral
  • Frequency: 2 Weekly
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor
Adult(Female)
  • Disease:
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 10 mg/kg
  • Dosage Route: Parenteral
  • Frequency: 2 Weekly
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor
Geriatric
  • Disease:
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 10 mg/kg
  • Dosage Route: Parenteral
  • Frequency: 2 Weekly
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor

Zybev Side Effects

Based on research, the following side effects have been observed when Zybev is used -

Severe

Moderate

Mild

  • Loss of appetite
  • Weight Loss
  • Rhinitis

Common

Unknown

Zybev Related Warnings

  • Is the use of Zybev safe for pregnant women?


    Zybev shows severe side effect on pregnant women. For this reason, pregnant women should only take it after taking medical advice.

    Severe
  • Is the use of Zybev safe during breastfeeding?


    Women who are breastfeeding, may experience serious side effects after taking Zybev. So it is adviced to consult the doctor before using it.

    Severe
  • What is the effect of Zybev on the Kidneys?


    There can be some harmful effects on your kidneys after taking Zybev. If you witness any side effects, discontinue its use. Consult your medical practitioner, do as he/she suggests.

    Moderate
  • What is the effect of Zybev on the Liver?


    The liver can be affected by Zybev. If you experience any unwanted effects of this drug, stop taking it and consult your doctor. You should restart Zybev only after medical advice.

    Moderate
  • What is the effect of Zybev on the Heart?


    The heart can be affected by Zybev. If you experience any unwanted effects of this drug, stop taking it and consult your doctor. You should restart the medicine only after medical advice.

    Moderate

Severe Interaction of Zybev with Other Drugs

Zybev should not be taken with following medicines due to severe side effects it may cause to patients -

Severe

Moderate


Zybev Contraindications

If you are suffering from any of the following diseases, you should not take Zybev unless your doctor advises you to do so -


Frequently asked Questions about Zybev

  • Is this Zybev habit forming or addictive?


    Forming a habit of Zybev has not been reported.

    No
  • Is it safe to drive or operate heavy machinery when consuming?


    After taking Zybev you may feel sleepy. So it is not advised to perform these activities.

    Dangerous
  • Is it safe?


    Yes, but take Zybev only as per medical advice.

    Safe, but take only on Doctor's advise
  • Is it able to treat mental disorders?


    No, Zybev cannot treat any kind of mental disorder.

    No

Zybev Interactions with Food and Alcohol

  • Interaction between Food and Zybev


    Taking Zybev with food does not cause any problems.

    Safe
  • Interaction between Alcohol and Zybev


    No research has been done on this till date. Therefore, it is not known what the effect of taking Zybev with alcohol will be.

    Unknown

See all substitutes for Zybev


This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
7 Years of Experience


References

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 224-225

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 871

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Avastin® (bevacizumab)

Therapeutic Goods Administration (TGA): Department of Health [Internet]. Governmet of Australia; Package leaflet information for the user; Avastin® (bevacizumab)


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₹19200
4ml Injection in 1 Vial