Zof

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  • Contains / Salt: Ofloxacin (200 mg)
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Zof (Estragen) Information

Zof (Estragen) is a prescription medicine that is available as a Tablet. Urinary Tract Infection, Ear Infection, Bacterial Infections are some of its major therapeutic uses. The alternative uses of Zof (Estragen) have also been explained below.

The optimal dosage of Zof (Estragen) is largely dependent on the individual's body weight, medical history, gender and age. Dosage also depends on the route of administration and your chief complaint for which the drug is prescribed. Refer to the dosage section for a detailed discussion.

While these are the most often observed Zof (Estragen) side effects, there are can be others also. These have been listed below. These side effects of Zof (Estragen) are usually temporary and subside with the completion of treatment. Please speak with your doctor if these side effects worsen or persist for a longer duration.

It is also important to note that Zof (Estragen) has a Moderate effect for pregnant women and Moderate effect on lactating mothers. Further, the section on Zof (Estragen) related warnings talks about Zof (Estragen)'s effects on the liver, heart and kidney.

Individuals suffering from medical conditions like Atrial Fibrillation, Heart Failure, Myasthenia Gravis (MG) must refrain from the use of Zof (Estragen) since this can cause severe adverse effects. Some other conditions that can be affected by Zof (Estragen) are listed in the contraindications section below.

Drug reaction of Zof (Estragen) with other medicines has been reported. See below for a complete list.

You should also be aware that Zof (Estragen) is not safe while driving, and is not addiction.



Zof (Estragen) Benefits & Uses

Zof (Estragen) is used to treat the following -

Other Benefits

Zof (Estragen) Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult
  • Disease: Skin Infections
  • Before or After Meal: After Meal
  • Single Maximum Dose: 400 mg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 2 daily
  • Course Duration: 10 days
  • Special Instructions: As prescribed by the doctor
Geriatric
  • Disease: Skin Infections
  • Before or After Meal: After Meal
  • Single Maximum Dose: 400 mg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 2 daily
  • Course Duration: 10 days
  • Special Instructions: As prescribed by the doctor
13 - 18 years (Adolescent)
  • Disease: Typhoid Fever
  • Before or After Meal: After Meal
  • Single Maximum Dose: 300 mg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 2 daily
  • Course Duration: 2 weeks
  • Special Instructions: As prescribed by the doctor


Zof (Estragen) Side Effects

Based on research, the following side effects have been observed when Zof (Estragen) is used -

Severe

  • Allergic reaction
  • Visual impairment
  • Steven-johnsons syndrome
  • Bronchospasm
  • Hearing Loss

Moderate

Mild

Zof (Estragen) Related Warnings

  • Is the use of Zof (Estragen) safe for pregnant women?


    Pregnant women may experience moderate side effects from Zof. It is best to stop taking Zof immediately and inform your doctor if you notice any discomfort.

    Moderate
  • Is the use of Zof (Estragen) safe during breastfeeding?


    Zof may lead to some side effects in breastfeeding women. If you witness any unusal symptoms after taking Zof, discontinue its use and call your doctor right away. Follow your doctor's advice regarding the use of Zof.

    Moderate
  • What is the effect of Zof (Estragen) on the Kidneys?


    Zof may have mild side effects on the kidneys.

    Mild
  • What is the effect of Zof (Estragen) on the Liver?


    Very few cases of side effects of Zof on the liver have been reported.

    Mild
  • What is the effect of Zof (Estragen) on the Heart?


    Zof is rarely harmful for the heart.

    Mild


Severe Interaction of Zof (Estragen) with Other Drugs

Zof (Estragen) should not be taken with following medicines due to severe side effects it may cause to patients -

Life Threatening

Severe

Moderate

Mild



Zof (Estragen) Contraindications

If you are suffering from any of the following diseases, you should not take Zof (Estragen) unless your doctor advises you to do so -



Frequently asked Questions about Zof (Estragen)

  • Is this Zof (Estragen) habit forming or addictive?


    Zof (Estragen) does not cause addiction.

    No
  • Is it safe to drive or operate heavy machinery when consuming?


    You may feel sleepy or tired after taking Zof (Estragen). So it is best to avoid driving.

    Dangerous
  • Is it safe?


    Zof (Estragen) should be used only after doctor's advice.

    Safe, but take only on Doctor's advise
  • Is it able to treat mental disorders?


    There is no benefit of taking Zof (Estragen) for mental disorders.

    No

Zof (Estragen) Interactions with Food and Alcohol

  • Interaction between Food and Zof (Estragen)


    Some foods when eaten with Zof (Estragen) can alter the onset of actions. Discuss this with your doctor.

    Mild
  • Interaction between Alcohol and Zof (Estragen)


    Taking alcohol with Zof (Estragen) can be dangerous.

    Severe


Frequently asked Questions about Zof (Estragen)

Question almost 5 years ago

Can I take Zof without consulting a doctor?

Dr. Uday Nath Sahoo MBBS , Internal Medicine

Zof is a prescription drug, hence do not take Zof without consulting doctor. It can be harmful to patients to take this medicine without a doctor's advice.

Question over 4 years ago

Can I take Zof for sinus infection?

Dr. Braj Bhushan Ojha BAMS , Gastroenterology, Dermatology, Psychiatry, Ayurveda, Sexology, Diabetology

Zof is not recommended as the first-line of drug for treating sinus infection. However, if there are no other alternatives available then you can take it, after doctor's advice.

Question over 4 years ago

Can I take Zof with metformin?

Take Zof if your doctor has prescribed it to you. However, keep a close check on blood sugar levels as metformin is known to cause hypoglycemia( sudden dip in blood sugar levels). In case you are experiencing severe hypoglycemia, please inform your doctor immediately.

Question over 4 years ago

Can Zof affect tendons and muscles?

Aakash Shah MBBS, MBBS , General Physician

Yes, long-term use of Zof can increase the risk of tendonitis and tendon rupture in some people. However, the exact mechanism of tendon rupture is not known. If you suffer from tendon rupture or any kind of muscular pain after consuming this drug, please consult your doctor immediately.

Question over 4 years ago

Does Zof contain penicillin?

Dr. Haleema Yezdani MBBS , General Physician

No, Zof does not contain penicillin. It is an antibiotic that belongs to the class of medication called fluoroquinolone. It used to treat several types of bacterial infection such as such as bronchitis, pneumonia, urinary, respiratory, skin, gastrointestinal, anthrax, bone, and eye infections.



See all substitutes for Zof (Estragen)


This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience


References

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 1400

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 713

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Floxin® (ofloxacin)

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Ocuflox® (ofloxacin)

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