Dr. Abhijit MBBS , General Physician

Yes, Instrel cause low blood pressure (hypotension) in a few cases only. It is a rare side effect of this drug. However, the exact cause of low blood pressure is unknown. If you are experiencing lightheadedness or blurry vision (symptoms of low blood pressure) after taking this drug then try to sit down and take rest for a while till it subsides.

Dr. Keshu Lal Damor MBBS , General Physician, Other, Obstetrics & Gynaecology

No, Instrel does not affect kidneys. It has not been reported to cause kidney damage (nephrotoxicity). If you have improper kidney function, then your doctor might change the dosage of your medications.

Dr. Gaurav MBBS , General Physician

Yes, Instrel may cause sweating but it occurs only in a few cases. It is a rare side effect of this drug. However, the exact cause of sweating is unknown but it is presumed that sweating occurs due to stimulation of sweat glands which causes excess sweating.

Dr. B. K. Agrawal MBBS, MD , Cardiology, General Physician, Internal Medicine

The dose of Instrel may vary from case to case basis depending on the severity of pain and the medical condition of the patient. You are advised to take it as per your doctor's instructions. It can be taken with or without food. Precautions must be taken in patients with depression, acute abdominal conditions, and improper liver or kidney function.

Dr. Kishan Barnwal MBBS , General Physician

Instrel contains tramadol which is an opioid analgesic (pain-killer). It is presumed that tramadol provides relief from pain by binding to certain receptors (mu-opioid receptors) in our brain and by preventing the reuptake of chemical messengers (neurotransmitters) serotonin and norepinephrine. In this way Instrel provides relief to the patient from moderate to severe pain.