Sibofix 550 Tablet

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Sibofix 550 Tablet Information

Sibofix 550 Tablet is a prescription medicine that is available as a Tablet. Primarily, it is used for the treatment of Hepatic Encephalopathy. Secondary and off-label uses of Sibofix 550 Tablet have also been mentioned below.

Medical history of the patient along with age and gender determines the dosage of Sibofix 550 Tablet. Dosage also depends on the route of administration and your chief complaint for which the drug is prescribed. For detailed information on this, read through the dosage section.

The most common side effects of Sibofix 550 Tablet are Flatulence, Bloating or fullness, Constipation. Besides the aforementioned side effects, there are other adverse effects of Sibofix 550 Tablet as well, which are listed below. Usually, these side effects of Sibofix 550 Tablet go away soon, and do not persist beyond the duration of the treatment. If, however, they worsen or do not go away, please speak with your physician.

Furthermore, you should know that effect of Sibofix 550 Tablet is Severe for pregnant women and Severe for women who are breastfeeding. In addition, Sibofix 550 Tablet's effects on the liver, heart and kidney are discussed below in the Sibofix 550 Tablet related warnings section.

The section on Sibofix 550 Tablet contraindications lists all such conditions.

Drug reaction of Sibofix 550 Tablet with other medicines has been reported. Refer to the list below for further details.

In addition to the above precautions for Sibofix 550 Tablet, it is important to know that it is safe while driving, and is habit-forming.



Sibofix 550 Tablet Benefits & Uses

Sibofix 550 Tablet is used to treat the following -

Main Benefits

Other Benefits

Sibofix 550 Tablet Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult
  • Disease: Traveler's Diarrhea
  • Before or After Meal: Either
  • Single Maximum Dose: 200 g
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 3 daily
  • Course Duration: 3 days
  • Special Instructions: As prescribed by the doctor
13 - 18 years (Adolescent)
  • Disease: Traveler's Diarrhea
  • Before or After Meal: Either
  • Single Maximum Dose: 200 mg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 2 daily
  • Course Duration: 3 days
  • Special Instructions: As prescribed by the doctor
Geriatric
  • Disease: Traveler's Diarrhea
  • Before or After Meal: Either
  • Single Maximum Dose: 200 mg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 3 daily
  • Course Duration: 3 days
  • Special Instructions: As prescribed by the doctor

Sibofix 550 Tablet Related Warnings

  • Is the use of Sibofix 550 Tablet safe for pregnant women?


    Sibofix shows severe side effect on pregnant women. For this reason, pregnant women should only take it after taking medical advice.

    Severe
  • Is the use of Sibofix 550 Tablet safe during breastfeeding?


    Sibofix may cause serious side effects in breastfeeding women, so do not take this drug without doctor's advice.

    Severe
  • What is the effect of Sibofix 550 Tablet on the Kidneys?


    Sibofix does not damage the kidneys.

    Safe
  • What is the effect of Sibofix 550 Tablet on the Liver?


    Very few cases of side effects of Sibofix on the liver have been reported.

    Mild
  • What is the effect of Sibofix 550 Tablet on the Heart?


    You can take Sibofix without any fear of damage to the heart.

    Safe


Sibofix 550 Tablet Contraindications

If you are suffering from any of the following diseases, you should not take Sibofix 550 Tablet unless your doctor advises you to do so -



Frequently asked Questions about Sibofix 550 Tablet

  • Is this Sibofix 550 Tablet habit forming or addictive?


    Sibofix 550 Tablet does not cause addiction.

    No
  • Is it safe to drive or operate heavy machinery when consuming?


    Sibofix 550 Tablet will not make you feel sleepy or drowsy. So you drive or operate machinery safely.

    Safe
  • Is it safe?


    Yes, but take Sibofix 550 Tablet only as per medical advice.

    Safe, but take only on Doctor's advise
  • Is it able to treat mental disorders?


    No, Sibofix 550 Tablet cannot treat any kind of mental disorder.

    No

Sibofix 550 Tablet Interactions with Food and Alcohol

  • Interaction between Food and Sibofix 550 Tablet


    Taking Sibofix 550 Tablet with food does not cause any problems.

    Safe
  • Interaction between Alcohol and Sibofix 550 Tablet


    Information about the interaction of Sibofix 550 Tablet and alcohol is not currently available because this topic has not been researched yet.

    Unknown


Frequently asked Questions about Sibofix 550 Tablet

Question over 4 years ago

Can I take Sibofix with amoxicillin?

Dr. Vipin Khadse MBBS , General Physician

Yes, Sibofix can be taken with amoxicillin. No clinically significant drug interaction has been reported between them. However, if you feel any discomfort after taking this drug along with amoxicillin then do not hesitate to inform your doctor.

Question almost 5 years ago

Does Sibofix cause weight gain?

Dr. Haleema Yezdani MBBS , General Physician

No, Sibofix does not cause weight gain. It has not been reported by the patients who are taking this drug but Sibofix has been reported to cause weight loss in a few patients with travelers’ diarrhea. If you notice any unusual rapid weight changes after taking this drug then discuss with it your doctor and follow his/her instructions.

Question over 5 years ago

What is Sibofix?

Dr. Anand Singh MBBS , General Physician

Sibofix is a brand name of rifaximin and it comes in the form of tablet and syrup. It is a prescription drug and a broad-spectrum antibiotic which is used in the prevention of travelers’ diarrhea (TD) caused by bacteria Escherichia coli and to reduce the risk of hepatic encephalopathy (a brain disorder that causes decline in functioning of the brain due to accumulation of ammonia in which results from the liver damage) along with lactulose. It is also used in the treatment of irritable bowel syndrome with diarrhea (IBS-D). 

Question over 4 years ago

Is Sibofix a penicillin?

Dr. Chinmaya Bal MBBS , General Physician

No, Sibofix is not a penicillin. It contains rifaximin which is a broad spectrum antibiotic and an analog of rifampicin. It is a prescription drug that is used in the treatment of travelers’ diarrhea (TD), hepatic encephalopathy, and irritable bowel syndrome with diarrhea (IBS-D).

Question about 4 years ago

Can I take Sibofix with loperamide?

Dr. MBBS , General Physician, Other, Obstetrics & Gynaecology

Yes, Sibofix can be taken with loperamide. Loperamide does not appear to interfere with the efficacy of Sibofix. Hence, it is alright to take them together. However, if you feel any discomfort after taking this drug do not hesitate to inform your doctor.



See all substitutes for Sibofix



This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience



References

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Xifaxan® (rifaximin)

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 681-683

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 1096-1097

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