E 2

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E 2 Information

E 2 is a commercial drug that is prescribed in the form of Gel. Post Menopausal Osteoporosis, Urethritis, Vaginal atrophy are some of its major therapeutic uses. E 2 also has some secondary and off-label uses. These are listed below.

The right dosage of E 2 depends on the age, gender, and medical history of the patient. Dosage also depends on the route of administration and your chief complaint for which the drug is prescribed. This information has been provided in detail in the dosage section.

E 2 also has some side effects, the most common being Weight gain, Metrorrhagia, Edema. Besides the aforementioned side effects, there are other adverse effects of E 2 as well, which are listed below. Such side effects of E 2 normally do not last long and go away once the treatment is completed. If, however, they worsen or do not go away, please speak with your physician.

In addition, E 2's effect is Severe during pregnancy and Severe for lactating mothers. Further, the section on E 2 related warnings talks about E 2's effects on the liver, heart and kidney.

E 2 can cause adverse effects in certain medical conditions. It is strongly recommended to avoid E 2 in conditions like High Blood Pressure, Blood Clotting Disorders, Thrombophlebitis. Other conditions have been mentioned below in the E 2 contraindications section.

Additionally, E 2 may also adversely react with other medicines. A complete list of these interactions is given below.

In addition to these precautions, you may also note that E 2 is safe while driving, and is is addictive in nature.



E 2 Benefits & Uses

E 2 is used to treat the following -

Other Benefits

E 2 Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult(Female)
  • Disease: Urethritis
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: Apply in appropriate quantity on affected area
  • Dosage Form: Gel
  • Dosage Route: Topical
  • Frequency: 1 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor
Geriatric
  • Disease: Urethritis
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: Apply in appropriate quantity on affected area
  • Dosage Form: Gel
  • Dosage Route: Parenteral
  • Frequency: 1 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor

E 2 Related Warnings

  • Is the use of E 2 safe for pregnant women?


    E 2 can cause severe side effects if taken during pregnancy, so, pregnant women should talk to their doctor before taking it.

    Severe
  • Is the use of E 2 safe during breastfeeding?


    E 2 may cause serious side effects in breastfeeding women, so do not take this drug without doctor's advice.

    Severe
  • What is the effect of E 2 on the Kidneys?


    Kidney can be affected by E 2. If you experience any unwanted effects of this drug, stop taking it. You should take it again only after medical advice.

    Moderate
  • What is the effect of E 2 on the Liver?


    E 2 has very mild side effects on the liver.

    Mild
  • What is the effect of E 2 on the Heart?


    You may experience side effects on your heart after taking E 2. If this happens, then discontinue its use. Consult your medical practitioner, and do as he/she suggests.

    Moderate


Severe Interaction of E 2 with Other Drugs

E 2 should not be taken with following medicines due to severe side effects it may cause to patients -

Severe

Moderate



E 2 Contraindications

If you are suffering from any of the following diseases, you should not take E 2 unless your doctor advises you to do so -



Frequently asked Questions about E 2

  • Is this E 2 habit forming or addictive?


    No, there is no any evidence that E 2 is addictive.

    No
  • Is it safe to drive or operate heavy machinery when consuming?


    Yes, it is safe to do these activities or work after taking E 2 as it does not make you drowsy.

    Safe
  • Is it safe?


    Yes, E 2 is safe but you must consult your doctor before taking it.

    Safe, but take only on Doctor's advise
  • Is it able to treat mental disorders?


    No, the use of E 2 in mental disorders is not effective.

    No

E 2 Interactions with Food and Alcohol

  • Interaction between Food and E 2


    There isn't any research available on the side effects of taking E 2 with food.

    Unknown
  • Interaction between Alcohol and E 2


    Information about the interaction of E 2 and alcohol is not currently available because this topic has not been researched yet.

    Unknown


Frequently asked Questions about E 2

Question almost 5 years ago

Can E 2 cause joint pain?

Dr. Saurabh Shakya MBBS , General Physician

Rarely, E 2 causes joint pain (arthralgia). However, the exact cause of joint pain is unknown. If you experience severe joint pain after taking this drug, take a mild painkiller, apply balm and complete rest even after this if the pain does not subside then discuss with your doctor immediately.

Question almost 5 years ago

Does E 2 cause breast enlargement?

Dr. Surender Kumar MBBS , General Physician

Yes, E 2 may cause breast enlargement if the E 2 is taken in high doses. It occurs due to hormonal effects of estradiol which causes the development of secondary female sex characteristics that includes breast enlargement. 

Question almost 5 years ago

Can E 2 cause hair loss?

Dr. Chinmaya Bal MBBS , General Physician

Yes, E 2 can cause hair loss. It is a rare side effect of this drug. The exact cause behind is unknown. If you are experiencing hair loss after taking this drug, then do discuss it with your doctor.

Question over 4 years ago

Can I take provera and E 2 together?

Dr. Vedprakash Verma MBBS, MD , Cardiology

Yes, provera and E 2 can be taken together. No clinically significant drug interaction has been reported between them. However, if you feel any discomfort after taking this drug along with provera then do not hesitate to inform your doctor.

Question over 4 years ago

Does E 2 cause acne?

Dr. Piyush Malav MBBS, MS , General Surgery

No, E 2 does not cause acne. It has not been reported by the patients who are taking this drug. In-fact acne might result due to hormonal imbalance (low estradiol levels) caused by menopause and E 2 is given to correct that hormonal imbalance.



See all substitutes for E 2


This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience


References

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Estrace (estradiol)

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 306-309

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 526-528



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